Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1 Acetate 1件: Acetate---43件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
2 Acetazolamide 1件: Acetazolamide2件: D00218 ,
D01196
13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬
7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬8件: 13, 86, 90, 115, 154, 155, 225, 230
3 Acetylcysteine 3件: Acetylcysteine; Mucomyst; N-acetylcysteine1件: D00221 --20件: 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
4 Aflibercept 2件: Aflibercept; Eylea1件: D09574 3件: PGF,
VEGFA,
VEGFB 💬
24件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬2件: 90, 166
5 Betamethasone 1件: Betamethasone7件: D00244 ,
D00972 ,
D01357 ,
D01402 ,
D01637 ,
D02032 ,
D02286
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬7件: 2, 28, 46, 83, 90, 96, 235
6 Brimonidine 2件: Brimonidine; Brimonidine Tartrate2件: D02076 ,
D07540
3件: ADRA2A,
ADRA2B,
ADRA2C 💬
2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬2件: 13, 90
7 Carbidopa 7件: Carbidopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬9件: 2, 4, 6, 13, 17, 90, 140, 164, 201
8 Cenegermin 3件: Cenegermin; OXERVATE; RhNGF1件: D11028 1件: NGFR 💬8件: Apoptosis - multiple species, Cytokine-cytokine receptor interaction, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer 💬2件: 53, 90
9 Cholesterol 1件: Cholesterol1件: D00040 --6件: 19, 90, 160, 259, 261, 310
10 Ciliary neurotrophic factor 1件: Ciliary neurotrophic factor---1件: 90
11 Cyclosporine 10件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
12 Cysteine 2件: Cysteine; Cysteine hydrochloride2件: D00026 ,
D02326
--11件: 6, 13, 19, 34, 84, 85, 88, 90, 254, 296, 310
13 Dapsone 1件: Dapsone1件: D00592 --6件: 35, 42, 60, 84, 90, 162
14 Dexamethasone 5件: Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
15 Doconexent 1件: Docosahexaenoic acid---10件: 6, 46, 48, 49, 90, 94, 113, 240, 299, 301
16 Dorzolamide 1件: Dorzolamide2件: D00653 ,
D07871
13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬
7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 90
17 Fluocinolone 1件: Fluocinolone---1件: 90
18 Fluocinolone acetonide 2件: Fluocinolone Acetonide; Iluvien1件: D01825 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90
19 Ginkgo biloba 3件: Ginkgo; Ginkgo biloba; Tanakan---5件: 6, 13, 18, 47, 90
20 Hydroxychloroquine 3件: Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; Plaquenil1件: D08050 --27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
21 Levodopa 8件: DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬
11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬8件: 2, 4, 6, 17, 90, 140, 164, 201
22 Lutein 1件: Lutein---3件: 13, 90, 164
23 Medical Cannabis 3件: Cannabis; Marijuana; Medical Cannabis---9件: 2, 6, 13, 19, 46, 90, 96, 97, 271
24 Melatonin 2件: Circadin; MELATONIN1件: D08170 2件: MTNR1A,
MTNR1B 💬
2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬12件: 6, 8, 13, 37, 46, 49, 90, 97, 144, 145, 149, 202
25 Minocycline 3件: Minocycline; Minocycline hydrochloride; Minomycin2件: D00850 ,
D05045
--14件: 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299
26 Nerve Growth Factor 1件: Nerve Growth Factor---3件: 3, 53, 90
27 Nilvadipine 1件: Nilvadipine1件: D01908 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 90
28 Oxygen 3件: Medical air; Nitrogen; Oxygen1件: D00003 --20件: 6, 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 168, 193, 226, 271, 294, 299, 330
29 Phosphate ion 1件: Phosphate---33件: 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
30 Phosphatidyl serine 0件: 1件: D04682 --4件: 6, 46, 90, 97
31 Sildenafil 6件: Mysildecard; Revatio; Sildenafil; SILDENAFIL CITRATE; SILDENAFILO; Viagra2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
32 Starch, corn 2件: Corn starch; Cornstarch1件: D05297 --3件: 49, 90, 257
33 Timrepigene emparvovec 1件: Timrepigene emparvovec---1件: 90
34 Tocopherol 2件: Tocoferol; Tocopherol1件: D02332 --6件: 13, 49, 90, 206, 257, 298
35 Triamcinolone 4件: Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide5件: D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
36 Unoprostone 1件: Unoprostone1件: D08661 1件: PTGFR 💬3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬1件: 90
37 Valproic acid 3件: Valproate; VALPROATE SODIUM; Valproic Acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬
17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
38 Vanillic acid 0件: ---3件: 90, 301, 302
39 Vitamin A 1件: Vitamin A2件: D00069 ,
D06543
2件: RARA,
RARB 💬
8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬3件: 13, 53, 90
40 Vitamin E 2件: Alpha-tocopherol; Vitamin E1件: D02331 --12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
41 Zuretinol acetate 1件: Zuretinol Acetate---1件: 90