Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 2件: ABATACEPT; Orencia1件: D03203 2件: CD80,
CD86 💬
12件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
2 Ademetionine 2件: SAM-e; SAMe1件: D07128 --2件: 6, 93
3 Alkaline Phosphatase 1件: Alkaline Phosphatase---4件: 46, 93, 97, 172
4 Atorvastatin 3件: ATORVASTATIN; Atorvastatin Calcium; Lipitor3件: D00258 ,
D00887 ,
D07474
1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
5 Azathioprine 3件: Azathioprine; Azatioprina; Imuran2件: D00238 ,
D03033
--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
6 Baricitinib 2件: Baricitinib; OLUMIANT1件: D10308 2件: JAK1,
JAK2 💬
35件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
7 Bezafibrate 1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬7件: 20, 93, 94, 160, 296, 316, 324
8 Budesonide 4件: BUDESONIDE; Entocort; Jorveza; Symbicort1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬9件: 66, 93, 94, 95, 96, 97, 98, 228, 299
9 Calcium 2件: Calcio; Calcium---30件: 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
10 Choline 1件: Choline1件: D07690 --4件: 93, 171, 193, 299
11 Cilofexor 1件: Cilofexor---2件: 93, 94
12 Colchicine 2件: COLCHICINA; Colchicine1件: D00570 9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬
10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬7件: 2, 42, 46, 56, 93, 210, 266
13 Cyclophosphamide 6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan2件: D00287 ,
D07760
--45件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
14 Cyclosporine 10件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
15 Denosumab 3件: DENOSUMAB; Prolia; XGEVA1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬7件: 46, 50, 93, 95, 96, 274, 299
16 Elafibranor 1件: ELAFIBRANOR1件: D11208 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
17 Emtricitabine 2件: Emtricitabine; TRUVADA1件: D01199 --4件: 25, 93, 265, 325
18 Ezetimibe 2件: Ezetimibe; Ezetrol1件: D01966 1件: NPC1L1 💬1件: Fat digestion and absorption 💬4件: 49, 79, 93, 260
19 Fenofibrate 1件: Fenofibrate1件: D00565 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬5件: 8, 79, 93, 94, 265
20 Gold 1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
21 GSK-2330672 0件: ---1件: 93
22 Lopinavir 2件: Kaletra; Lopinavir1件: D01425 --2件: 93, 265
23 Magnesium 1件: Magnesium---21件: 3, 6, 11, 13, 15, 46, 51, 64, 70, 93, 97, 111, 166, 225, 235, 256, 284, 291, 296, 297, 298
24 Methionine 3件: Butanoic acid; L-methionine; Methionine2件: D00019 ,
D04983
--7件: 34, 75, 84, 93, 229, 298, 300
25 Methotrexate 6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; Metotrexato; Méthotrexate2件: D00142 ,
D02115
2件: DHFR,
DHFR2 💬
5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
26 Methylprednisolone 4件: Medrol; Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE6件: D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
27 Minodronic acid 2件: Minodronate; Minodronic acid---4件: 6, 46, 93, 95
28 Modafinil 2件: Modafinil; Provigil1件: D01832 --5件: 6, 13, 49, 93, 113
29 Moexipril 1件: Moexipril2件: D00623 ,
D08225
1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 93
30 Mycophenolate mofetil 3件: CellCept; Mycophenolate mofetil; Mycophenolate mofetil TEVA3件: D00752 ,
D05094 ,
D05095
2件: IMPDH1,
IMPDH2 💬
3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
31 Mycophenolic acid 5件: Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic1件: D05096 2件: IMPDH1,
IMPDH2 💬
3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
32 norUrsodeoxycholic acid 2件: Norucholic acid; NorUrsodeoxycholic Acid---2件: 93, 94
33 Obeticholic acid 4件: 6-ECDCA; 6-ethylchenodeoxycholic acid; Obeticholic Acid; Ocaliva1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬3件: 93, 265, 296
34 Pemafibrate 1件: Pemafibrate1件: D10711 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
35 Pentoxifylline 1件: Pentoxifylline1件: D00501 --10件: 26, 56, 84, 93, 96, 113, 220, 222, 296, 298
36 Phenylbutyric acid 4件: 4-phenylbutyrate; Pheburane; PHENYLBUTYRATE; Sodium phenylbutyrate---14件: 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338
37 Pyridoxine 2件: Pyridoxine; Vitamin B62件: D02179 ,
D08454
--5件: 6, 93, 145, 206, 320
38 Raltegravir 2件: ISENTRESS; Raltegravir1件: D06676 --4件: 13, 26, 93, 265
39 Rifampicin 2件: Rifampicin; Rifampin1件: D00211 --9件: 6, 13, 17, 46, 84, 86, 93, 299, 338
40 Rifaximin 3件: Rifaximin; RIFAXIMINA; Xifaxan1件: D02554 --8件: 6, 65, 93, 94, 96, 97, 99, 296
41 Risedronic acid 3件: Risedronate; Risedronate Sodium; Risedronic acid3件: D00942 ,
D03234 ,
D08484
1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 46, 50, 66, 93, 95, 96, 107, 113, 274
42 Rituximab 6件: MabThera; Rituxan; RITUXIMAB; Rixathon; Ruxience; TRUXIMA1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬49件: 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
43 Saroglitazar 1件: Saroglitazar---1件: 93
44 Seladelpar 1件: SELADELPAR1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94
45 Tauroursodeoxycholic acid 2件: TAUROURSODEOXYCHOLIC ACID; TUDCA1件: D11836 --4件: 2, 13, 93, 299
46 Tenofovir 1件: Tenofovir1件: D06074 --6件: 2, 13, 25, 93, 265, 325
47 Tenofovir disoproxil 4件: Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA1件: D01982 --2件: 93, 265
48 Tetrathiomolybdate 1件: Tetrathiomolybdate---3件: 85, 93, 171
49 Thiamine 2件: THIAMINE; Vitamin B11件: D08580 --5件: 8, 13, 93, 145, 265
50 Tigecycline 1件: Tigecycline1件: D01079 --1件: 93
51 Tropifexor 1件: Tropifexor1件: D11548 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
52 Ursodeoxycholic acid 4件: UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬14件: 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299
53 Ustekinumab 2件: Stelara; Ustekinumab1件: D09214 3件: IL12A,
IL12B,
IL23A 💬
28件: African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
54 Vitamin D 3件: Calciferol; Cod liver oil; Vitamin D---24件: 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299
55 Volixibat 1件: Volixibat1件: D11007 --2件: 93, 94
56 Zoledronic acid 4件: ACLASTA; Zoledronate; ZOLEDRONIC ACID; Zometa4件: D01968 ,
D06378 ,
D06379 ,
D08689
1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333