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Target Gene/Pathway
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Showing 1 to 5 of 5 drugs
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DrugBank
薬物名（臨床試験情報から抽出）
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Diphenhydramine
(
Ibuprofen
PM)
2件:
Diphenhydramine
Diphenhydramine
;
Diphenhydramine hydrochloride
1件:
Diphenhydramine
Diphenhydramine
💬
1. Diphenhydramine
×
Name
Other Names
Diphenhydramine
Diphenhydramine (JP18/INN)
Restamin (TN)
ジフェンヒドラミン
レスタミン
1件:
HRH1
HRH1
💬
1. Diphenhydramine
×
Name
Full Name
HRH1
histamine receptor H1
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Neuroactive ligand-receptor interaction
💬
3件:
Calcium signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Neuroactive ligand-
...
8件:
11
11
,
13
,
49
,
51
,
70
,
86
,
222
,
256
💬
1. Diphenhydramine
×
告示番号
日本語名
英語名
11
重症筋無力症
Myasthenia gravis
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
49
全身性エリテマトーデス
Systemic lupus erythematosus
51
全身性強皮症
Scleroderma
70
広範脊柱管狭窄症
Spinal stenosis
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
256
筋型糖原病
Muscle glycogenosis
2
Famotidine
(
Ibuprofen
and famotidine)
2件:
FAMOTIDINA
FAMOTIDINA
;
Famotidine
1件:
Famotidine
Famotidine
💬
2. Famotidine
×
Name
Other Names
Famotidine
Famotidine (JP18/USP/INN)
Fluxid (TN)
Pepcid (TN)
ファモチジン
ガスター
1件:
HRH2
HRH2
💬
2. Famotidine
×
Name
Full Name
HRH2
histamine receptor H2
3件:
Calcium signaling pathway
Calcium signaling pathway
,
Gastric acid secretion
,
Neuroactive ligand-receptor interaction
💬
6件:
6
6
,
46
,
61
,
86
,
98
,
107
💬
2. Famotidine
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
46
悪性関節リウマチ
Malignant rheumatoid arthritis
61
自己免疫性溶血性貧血
Autoimmune hemolytic anemia
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
98
好酸球性消化管疾患
Eosinophilic gastrointestinal disease
107
若年性特発性関節炎
Juvenile idiopathic arthritis
3
Ibuprofen
2件:
Ibuprofen
Ibuprofen
;
IBUPROFEN 200MG
1件:
Ibuprofen
Ibuprofen
💬
3.
Ibuprofen
×
Name
Other Names
Ibuprofen
Ibuprofen (JP18/USP/INN)
Advil (TN)
Motrin (TN)
CALDOLOR
IBU
イブプロフェン
ブルフェン
2件:
PTGS1
PTGS1
,
PTGS2
💬
3.
Ibuprofen
×
Name
Full Name
PTGS1
prostaglandin-endoperoxide synthase 1
PTGS2
prostaglandin-endoperoxide synthase 2
23件:
Alzheimer disease
Alzheimer disease
,
Arachidonic acid metabolism
,
C-type lectin receptor signaling pathway
,
Chemical carcinogenesis - DNA adducts
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
IL-17 signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Leishmaniasis
,
Metabolic pathways
,
MicroRNAs in cancer
,
NF-kappa B signaling pathway
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Platelet activation
,
Regulation of lipolysis in adipocytes
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Small cell lung cancer
,
TNF signaling pathway
,
VEGF signaling pathway
💬
23件:
Alzheimer disease
,
Arachidonic acid metabolism
,
C-type lectin receptor signaling pathway
,
Chemi
...
7件:
13
13
,
46
,
65
,
107
,
113
,
271
,
299
💬
3.
Ibuprofen
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
46
悪性関節リウマチ
Malignant rheumatoid arthritis
65
原発性免疫不全症候群
Primary immunodeficiency
107
若年性特発性関節炎
Juvenile idiopathic arthritis
113
筋ジストロフィー
Muscular dystrophy
271
強直性脊椎炎
Ankylosing spondylitis
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
4
Oxycodone
(Oxycodone hydrochloride and
Ibuprofen
)
2件:
Oxycodone
Oxycodone
;
OXYCODONE HYDROCHLORIDE
1件:
Oxycodone
Oxycodone
💬
4. Oxycodone
×
Name
Other Names
Oxycodone
Oxycodone (USAN/INN)
XTAMPZA
オキシコドン
3件:
OPRD1
OPRD1
,
OPRK1
,
OPRM1
💬
4. Oxycodone
×
Name
Full Name
OPRD1
opioid receptor delta 1
OPRK1
opioid receptor kappa 1
OPRM1
opioid receptor mu 1
5件:
Estrogen signaling pathway
Estrogen signaling pathway
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Sphingolipid signaling pathway
,
cGMP-PKG signaling pathway
💬
5件:
Estrogen signaling pathway
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Sphingo
...
5件:
6
6
,
13
,
70
,
226
,
298
💬
4. Oxycodone
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
70
広範脊柱管狭窄症
Spinal stenosis
226
間質性膀胱炎（ハンナ型）
Interstitial cystitis with Hunners ulcer
298
遺伝性膵炎
Hereditary pancreatitis
5
Pseudoephedrine
(
Ibuprofen
Cold and Sinus)
1件:
Pseudoephedrine
Pseudoephedrine
1件:
Pseudoephedrine
Pseudoephedrine
💬
5. Pseudoephedrine
×
Name
Other Names
Pseudoephedrine
Pseudoephedrine (INN)
Neodurasina (TN)
Acunaso (TN)
プソイドエフェドリン
9件:
ADRA1A
ADRA1A
,
ADRA1B
,
ADRA1D
,
ADRA2A
,
ADRA2B
,
ADRA2C
,
ADRB1
,
ADRB2
,
ADRB3
💬
5. Pseudoephedrine
×
Name
Full Name
ADRA1A
adrenoceptor alpha 1A
ADRA1B
adrenoceptor alpha 1B
ADRA1D
adrenoceptor alpha 1D
ADRA2A
adrenoceptor alpha 2A
ADRA2B
adrenoceptor alpha 2B
ADRA2C
adrenoceptor alpha 2C
ADRB1
adrenoceptor beta 1
ADRB2
adrenoceptor beta 2
ADRB3
adrenoceptor beta 3
14件:
AMPK signaling pathway
AMPK signaling pathway
,
Adrenergic signaling in cardiomyocytes
,
Calcium signaling pathway
,
Chemical carcinogenesis - receptor activation
,
Dilated cardiomyopathy
,
Gap junction
,
Neuroactive ligand-receptor interaction
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Salivary secretion
,
Thermogenesis
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
14件:
AMPK signaling pathway
,
Adrenergic signaling in cardiomyocytes
,
Calcium signaling pathway
,
Chem
...
1件:
17
17
💬
5. Pseudoephedrine
×
告示番号
日本語名
英語名
17
多系統萎縮症
Multiple system atrophy