KEGG DRUG

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No.	DrugBank	薬物名（臨床試験情報から抽出）	KEGG DRUG	KEGG GENES	KEGG PATHWAY	指定難病告示番号
1	Amlodipine (Amlodipine and Valsartan)	1件: Amlodipine	1件: Amlodipine 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬	4件: 13, 51, 67, 298 💬
2	Hydrochlorothiazide (PMS-valsartan-hctz)	2件: Esidrix; Hydrochlorothiazide	1件: Hydrochlorothiazide 💬	1件: SLC12A3 💬	-	4件: 13, 67, 225, 235 💬
3	Valsartan	3件: Diovan; Entresto; Valsartan	1件: Valsartan 💬	1件: AGTR1 💬	16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬	7件: 57, 58, 66, 75, 218, 222, 224 💬