Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1 D-glucose 2件: D-glucose; Glucose1件: D00009 --3件: 49, 86, 88
2 D-Proline 1件: D-Proline---1件: 97
3 D-Serine 1件: D-Serine---1件: 6
4 Dabigatran 1件: Dabigatran1件: D09707 1件: F2 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬4件: 51, 85, 91, 124
5 Dabigatran etexilate 1件: Dabigatran etexilate1件: D07144 1件: F2 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬1件: 51
6 Dabrafenib 1件: Dabrafenib1件: D10064 1件: BRAF 💬44件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Bladder cancer, Breast cancer, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanoma, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Regulation of actin cytoskeleton, Renal cell carcinoma, Serotonergic synapse, Thyroid cancer, Vascular smooth muscle contraction, cAMP signaling pathway, mTOR signaling pathway 💬1件: 34
7 Daclizumab 3件: Daclizumab; Zenapax; Zinbryta1件: D03639 1件: IL2RA 💬11件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬8件: 13, 56, 60, 65, 97, 107, 283, 284
8 Dalfampridine 7件: 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra1件: D04127 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬
4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬5件: 3, 4, 6, 13, 14
9 Dalteparin 2件: Dalteparin; Fragmin---1件: 222
10 Danazol 1件: Danazol1件: D00289 3件: AR,
ESR1,
PGR 💬
12件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬5件: 60, 63, 64, 65, 285
11 Danicopan 1件: DANICOPAN1件: D11641 1件: CFD 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬2件: 62, 222
12 Dantrolene 2件: Dantrolene; Dantrolene sodium2件: D02274 ,
D02347
--2件: 13, 233
13 Dapagliflozin 1件: Dapagliflozin1件: D08897 --2件: 49, 222
14 Dapirolizumab pegol 1件: Dapirolizumab pegol---2件: 13, 49
15 Dapsone 1件: Dapsone1件: D00592 --6件: 35, 42, 60, 84, 90, 162
16 Daratumumab 2件: DARATUMUMAB; Darzalex1件: D10777 1件: CD38 💬7件: Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬5件: 16, 28, 49, 63, 222
17 Darifenacin 2件: Darifenacin; Emselex2件: D01699 ,
D03654
1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 6, 13
18 Darunavir 1件: Darunavir1件: D03656 --1件: 2
19 Darvadstrocel 2件: Alofisel; DARVADSTROCEL1件: D11397 --1件: 96
20 Dasatinib 1件: Dasatinib2件: D03658 ,
D06414
8件: ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬
77件: Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬2件: 51, 85
21 Daunorubicin 1件: Daunorubicin2件: D01264 ,
D07776
2件: TOP2A,
TOP2B 💬
1件: Platinum drug resistance 💬1件: 65
22 Davunetide 1件: Davunetide1件: D09401 --3件: 5, 7, 127
23 Deanol 1件: Deanol1件: D07777 --1件: 6
24 Decitabine 1件: Decitabine1件: D03665 3件: DNMT1,
DNMT3A,
DNMT3B 💬
3件: Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer 💬3件: 13, 60, 63
25 Deferasirox 2件: DEFERASIROX; EXJADE1件: D03669 --3件: 254, 284, 286
26 Deferiprone 2件: DEFERIPRONE; Ferriprox1件: D07416 --6件: 2, 6, 18, 120, 122, 233
27 Deferitazole 1件: Deferitazole1件: D10388 --1件: 284
28 Deferoxamine 2件: Deferoxamine; DESFERAL2件: D01186 ,
D03670
--3件: 46, 284, 286
29 Deflazacort 1件: Deflazacort1件: D03671 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 30, 113
30 Delorazepam 0件: 1件: D07784 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 6, 46, 97
31 Denosumab 3件: DENOSUMAB; Prolia; XGEVA1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬7件: 46, 50, 93, 95, 96, 274, 299
32 Denufosol 1件: Denufosol---1件: 299
33 Deoxycholic acid 1件: Kybella1件: D10781 --1件: 34
34 Dersalazine 1件: Dersalazine---1件: 97
35 Desflurane 1件: Desflurane1件: D00546 --2件: 22, 296
36 Desipramine 1件: Desipramine2件: D00812 ,
D07791
2件: SLC6A2,
SLC6A4 💬
2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 120, 156
37 Desloratadine 1件: Desloratadine1件: D03693 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 13
38 Desmopressin 5件: DDAVP; Desmopressin; Desmopressin acetate; Desmopressine; Minirin2件: D00291 ,
D02235
2件: AVPR2,
F8 💬
4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬6件: 6, 64, 72, 75, 225, 288
39 Desogestrel 2件: Desogestrel; Désogestrel1件: D02367 2件: ESR1,
PGR 💬
11件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬1件: 230
40 Desoxyribonuclease 1件: Desoxyribonuclease---1件: 299
41 Deucravacitinib 1件: Deucravacitinib1件: D11817 1件: TYK2 💬16件: Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis 💬2件: 96, 97
42 Deutetrabenazine 1件: Deutetrabenazine1件: D10701 1件: SLC18A2 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 8
43 Deutivacaftor 1件: DEUTIVACAFTOR1件: D11423 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
44 Dexamethasone 5件: Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
45 Dexchlorpheniramine 1件: Dexchlorpheniramine1件: D07803 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬2件: 13, 49
46 Dexlansoprazole 1件: Dexlansoprazole1件: D08903 2件: ATP4A,
ATP4B 💬
4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬1件: 98
47 Dexmedetomidine 4件: Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE2件: D00514 ,
D01205
3件: ADRA2A,
ADRA2B,
ADRA2C 💬
2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
48 Dexpramipexole 1件: Dexpramipexole1件: D09886 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬
11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 2
49 Dexrazoxane 1件: Dexrazoxane1件: D03730 2件: TOP2A,
TOP2B 💬
1件: Platinum drug resistance 💬1件: 13
50 Dextran 1件: Dextran1件: D00060 --5件: 2, 62, 79, 96, 97
51 Dextromethorphan 4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta3件: D00848 ,
D03742 ,
D03744
6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬
20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
52 Dextrose, unspecified form 2件: Dextrose; Glucose---19件: 2, 6, 13, 49, 50, 56, 60, 65, 70, 75, 86, 88, 96, 160, 195, 226, 254, 257, 299
53 Dezamizumab 1件: Dezamizumab1件: D11471 --1件: 28
54 Diacerein 1件: Diacerein1件: D07270 --3件: 36, 46, 63
55 Diazepam 1件: Diazepam1件: D00293 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 46, 155, 298
56 Diazoxide 1件: Diazoxide1件: D00294 2件: ABCC8,
KCNJ11 💬
4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬2件: 13, 193
57 Dibotermin alfa 1件: BMP-21件: D03779 1件: BMPR2 💬7件: Axon guidance, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hippo signaling pathway, MicroRNAs in cancer, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬1件: 34
58 Dichloroacetic acid 1件: Dichloroacetate---1件: 86
59 Dichlorobenzene 0件: ---1件: 40
60 Dichloroisoproterenol 0件: ---2件: 6, 299
61 Diclofenac 3件: Diclofenac; Diclofenac sodium; Diclofenac SR3件: D00903 ,
D00904 ,
D07816
2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬5件: 13, 34, 46, 78, 271
62 Diclofenamide 1件: Dichlorphenamide1件: D00518 13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬
7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 114
63 Dicloxacillin 1件: DICLOXACILLIN2件: D02137 ,
D02348
--1件: 299
64 Didanosine 1件: Didanosine1件: D00296 --2件: 25, 265
65 Diethyl ether 1件: Ether1件: D01772 --1件: 235
66 Diflunisal 1件: Diflunisal1件: D00130 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 28
67 Digitoxin 1件: Digitoxin1件: D00297 4件: ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬
18件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 299
68 Digoxin 1件: Digoxin1件: D00298 4件: ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬
18件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 8, 46, 210
69 Dihydrocodeine 0件: 2件: D01481 ,
D07831
1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 310
70 Dihydroergotoxine 1件: Dihydroergotoxine1件: D07839 --1件: 6
71 Dihydrotachysterol 0件: 1件: D00299 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 6, 85
72 Diltiazem 2件: Diltiazem; Diltiazem Hydrochloride3件: D00616 ,
D03830 ,
D07845
4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 51, 58, 86
73 Dimercaprol 0件: 1件: D00167 --5件: 49, 51, 84, 85, 299
74 Dimethyl fumarate 3件: DIMETHYL FUMARATE; Dimethylfumarat; TECFIDERA1件: D03846 1件: KEAP1 💬6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬5件: 13, 49, 51, 86, 296
75 Dimethyl sulfoxide 2件: Dimethyl sulfoxide; DMSO1件: D01043 --1件: 226
76 Dimethyltryptamine 0件: ---1件: 13
77 Diosmin 1件: DIOSMIN1件: D07858 --1件: 265
78 Diphenhydramine 2件: Diphenhydramine; Diphenhydramine hydrochloride6件: D00300 ,
D00669 ,
D02419 ,
D03285 ,
D03360 ,
D03854
1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬10件: 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
79 Diphenylpyraline 0件: 3件: D01172 ,
D01627 ,
D07862
1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 98
80 Dipivefrin 2件: Dipivefrin; Dipivefrine1件: D02349 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬
14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
81 Dipraglurant 1件: Dipraglurant---1件: 6
82 Dipyridamole 1件: Dipyridamole1件: D00302 2件: PDE4A,
PDE5A 💬
6件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 46, 49, 51, 66, 96, 224
83 Diquafosol 1件: Diquafosol---1件: 53
84 Diroximel fumarate 1件: Diroximel fumarate1件: D11154 --1件: 13
85 Dirucotide 1件: Dirucotide1件: D09396 --1件: 13
86 Dithiopyr 1件: DIMENSION---1件: 55
87 Ditiocarb 1件: Diethyldithiocarbamate---1件: 169
88 DL-dimyristoylphosphatidylcholine 1件: ABELCET---1件: 299
89 DL-dimyristoylphosphatidylglycerol 1件: ABELCET---1件: 299
90 Dobutamine 2件: Dobutamin; Dobutamine4件: D00632 ,
D03879 ,
D03880 ,
D03881
1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 57, 58, 215
91 Doconexent 1件: Docosahexaenoic acid---10件: 6, 46, 48, 49, 90, 94, 113, 240, 299, 301
92 Dolutegravir 2件: Dolutegravir; Triumeq1件: D10066 --2件: 2, 265
93 Domagrozumab 1件: PF-062526161件: D11047 1件: MSTN 💬1件: Cytokine-cytokine receptor interaction 💬1件: 113
94 Domperidone 1件: Domperidone2件: D01745 ,
D07868
1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 13, 17, 51, 230
95 Donepezil 3件: Aricept; Donepezil; Donepezil hydrochloride2件: D00670 ,
D07869
1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
96 Dopamine 2件: Dopamina; Dopamine2件: D00633 ,
D07870
5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬
11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 6, 7, 74, 299
97 Doravirine 1件: Doravirine1件: D10624 --1件: 265
98 Doripenem 2件: DORIBAX; Doripenem1件: D03895 --1件: 299
99 Dornase alfa 3件: Dornase alfa; Dornase alpha; Pulmozyme1件: D03896 --2件: 53, 299
100 Dorzolamide 1件: Dorzolamide2件: D00653 ,
D07871
13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬
7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 90
101 Dotatate 2件: DOTA-TATE; Dotatate---4件: 41, 75, 84, 238
102 Dotatate gallium Ga-68 1件: 68Ga-DOTATATE---3件: 75, 84, 238
103 Doxazosin 2件: CARDURA; DOXAZOSIN2件: D00608 ,
D07874
3件: ADRA1A,
ADRA1B,
ADRA1D 💬
7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 57, 67
104 Doxepin 1件: Doxepin2件: D00814 ,
D07875
3件: HRH1,
SLC6A2,
SLC6A4 💬
5件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 6
105 Doxorubicin 2件: Doxorubicin; Doxorubicin Hydrochloride1件: D03899 2件: TOP2A,
TOP2B 💬
1件: Platinum drug resistance 💬5件: 26, 28, 34, 65, 331
106 Doxycycline 4件: Doxycyclin; Doxycycline; Doxycycline Hyclate; Doxycycline Tablets5件: D00307 ,
D02129 ,
D03903 ,
D03904 ,
D07876
--16件: 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
107 Drisapersen 1件: Drisapersen1件: D10114 1件: DMD 💬4件: Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113
108 Dronabinol 4件: DELTA-9-TETRAHYDROCANNABINOL; DRONABINOL; Sativex; Tetrahydrocannabinol1件: D00306 2件: CNR1,
CNR2 💬
4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬8件: 2, 8, 13, 36, 46, 96, 271, 298
109 Droxidopa 4件: DOPS; Droxidopa; L-DOPS; Northera1件: D01277 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬
14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 5, 6, 17, 169, 170
110 Dulaglutide 2件: Dulaglutide; Trulicity1件: D09889 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 13, 299
111 Duloxetine 3件: Cymbalta; DULOXETINE; Duloxetine hydrochloride2件: D01179 ,
D07880
2件: SLC6A2,
SLC6A4 💬
2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 13
112 Dupilumab 2件: DUPILUMAB; Dupixent1件: D10354 1件: IL4R 💬8件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬4件: 51, 98, 160, 162
113 Durvalumab 1件: Durvalumab1件: D10808 1件: CD274 💬2件: Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬1件: 85
114 Dutasteride 2件: Dutasterida; DUTASTERIDE1件: D03820 2件: SRD5A1,
SRD5A2 💬
3件: Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬2件: 1, 2
115 Duvoglustat 3件: 1-deoxynojirimycin; Deoxynojirimycin; Duvoglustat1件: D09605 1件: GAA 💬4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬1件: 256
116 Dydrogesterone 1件: DYDROGESTERONE1件: D01217 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13