Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1 Valaciclovir 1件: Valacyclovir3件: D00398 ,
D08664 ,
D10518
--1件: 65
2 Valbenazine 1件: Valbenazine1件: D10675 1件: SLC18A2 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 8
3 Valdecoxib 1件: Valdecoxib1件: D02709 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 46
4 Valerian 1件: Valerian---1件: 6
5 Valganciclovir 1件: Valganciclovir1件: D02495 --6件: 28, 60, 85, 97, 299, 331
6 Valproic acid 3件: Valproate; VALPROATE SODIUM; Valproic Acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬
17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
7 Valsartan 3件: Diovan; Entresto; Valsartan1件: D00400 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 57, 58, 66, 75, 218, 222, 224
8 Vamorolone 1件: Vamorolone1件: D11000 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 97, 113
9 Vancomycin 1件: Vancomycin2件: D00212 ,
D00926
--7件: 46, 70, 94, 96, 97, 296, 299
10 Vanillic acid 0件: ---3件: 90, 301, 302
11 Vardenafil 3件: Levitra; Vardenafil; Vardenafilo3件: D02731 ,
D03260 ,
D08668
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬3件: 13, 86, 299
12 Varenicline 2件: Champix; Varenicline1件: D08669 2件: CHRNA4,
CHRNB2 💬
4件: Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬2件: 6, 18
13 Varicella zoster vaccine (live/attenuated) 1件: Zostavax---2件: 46, 49
14 Varicella zoster vaccine (recombinant) 1件: Shingrix---3件: 46, 96, 97
15 Vasopressin 1件: Vasopressin1件: D00101 3件: AVPR1A,
AVPR1B,
AVPR2 💬
5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬1件: 210
16 Vatelizumab 1件: Vatelizumab---2件: 13, 97
17 Vatiquinone 1件: VATIQUINONE1件: D10407 --2件: 18, 21
18 VB-201 1件: VB-201---1件: 97
19 Vedolizumab 2件: ENTYVIO; VEDOLIZUMAB1件: D08083 2件: ITGA4,
ITGB7 💬
15件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬3件: 94, 96, 97
20 Velaglucerase alfa 3件: GA-GCB; VELAGLUCERASE ALFA; VPRIV1件: D09029 1件: GBA 💬4件: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬1件: 19
21 Veledimex 1件: Veledimex1件: D10678 --1件: 51
22 Velmanase alfa 3件: LAMAZYM; RhLAMAN; VELMANASE ALFA1件: D11024 1件: MAN2B1 💬2件: Lysosome, Other glycan degradation 💬1件: 19
23 Veltuzumab 1件: Veltuzumab1件: D09031 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬1件: 46
24 Velusetrag 1件: Velusetrag1件: D09693 1件: HTR4 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, cAMP signaling pathway 💬1件: 99
25 Venetoclax 1件: Venetoclax1件: D10679 1件: BCL2 💬43件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Autophagy - animal, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Colorectal cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Lipid and atherosclerosis, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prostate cancer, Protein processing in endoplasmic reticulum, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway 💬1件: 28
26 Venglustat 2件: GENZ-682452; Venglustat1件: D11633 1件: UGCG 💬2件: Metabolic pathways, Sphingolipid metabolism 💬3件: 6, 19, 67
27 Venlafaxine 2件: Venlafaxine; Venlafaxine Hydrochloride2件: D00821 ,
D08670
2件: SLC6A2,
SLC6A4 💬
2件: Serotonergic synapse, Synaptic vesicle cycle 💬3件: 6, 13, 46
28 Verapamil 2件: VERAPAMIL; Verapamil SR2件: D00619 ,
D02356
4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 96, 140, 167
29 Verdiperstat 1件: Verdiperstat1件: D11684 1件: MPO 💬5件: Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬3件: 2, 17, 127
30 Vestronidase alfa 3件: Mepsevii; Recombinant human beta-glucuronidase; Vestronidase alfa1件: D11004 1件: GUSB 💬8件: Ascorbate and aldarate metabolism, Biosynthesis of cofactors, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome, Metabolic pathways, Pentose and glucuronate interconversions, Porphyrin metabolism 💬1件: 19
31 Vibrio cholerae Inaba 48 classical biotype, heat inactivated 1件: Dukoral---1件: 97
32 Vibrio cholerae Inaba 6973 El Tor biotype, formalin inactivated 1件: Dukoral---1件: 97
33 Vibrio cholerae Ogawa 50 classical biotype, formalin inactivated 1件: Dukoral---1件: 97
34 Vibrio cholerae Ogawa 50 classical biotype, heat inactivated 1件: Dukoral---1件: 97
35 Vidofludimus 1件: Vidofludimus---5件: 13, 46, 94, 96, 97
36 Vigabatrin 2件: Sabril; VIGABATRIN1件: D00535 1件: ABAT 💬7件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬2件: 145, 158
37 Vilobelimab 2件: IFX-1; Vilobelimab1件: D11838 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬3件: 43, 44, 269
38 Viltolarsen 1件: VILTOLARSEN1件: D11528 1件: DMD 💬4件: Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113
39 Vinblastine 2件: Vinblastine; Vinblastine sulfate2件: D01068 ,
D08675
9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬
10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬2件: 34, 65
40 Vincristine 2件: Vincristine; Vincristine Sulfate2件: D02197 ,
D08679
9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬
10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬4件: 26, 34, 65, 331
41 Visilizumab 1件: Visilizumab1件: D06314 3件: CD3D,
CD3E,
CD3G 💬
11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬2件: 96, 97
42 Vismodegib 2件: Erivedge; VISMODEGIB1件: D09992 1件: SMO 💬5件: Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer 💬1件: 85
43 Vitamin A 1件: Vitamin A2件: D00069 ,
D06543
2件: RARA,
RARB 💬
8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬3件: 13, 53, 90
44 Vitamin D 3件: Calciferol; Cod liver oil; Vitamin D---24件: 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299
45 Vitamin E 2件: Alpha-tocopherol; Vitamin E1件: D02331 --12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
46 Vobarilizumab 1件: Vobarilizumab1件: D11005 --1件: 49
47 Voclosporin 1件: Voclosporin1件: D09033 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬1件: 222
48 Volanesorsen 1件: Volanesorsen1件: D11648 1件: APOC3 💬2件: Cholesterol metabolism, PPAR signaling pathway 💬1件: 265
49 Volixibat 1件: Volixibat1件: D11007 --2件: 93, 94
50 Von Willebrand factor human 7件: Alphanate; Factor von Willebrand; HUMAN VON WILLEBRAND FACTOR; Humate-P; VON WILLEBRAND FACTOR; Voncento; WILATE---2件: 64, 288
51 Vonicog alfa 3件: Veyvondi; VON WILLEBRAND FACTOR; VONICOG ALFA1件: D08681 --1件: 288
52 Vonoprazan 1件: Vonoprazan1件: D11784 2件: ATP4A,
ATP4B 💬
4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 63, 98
53 Voriconazole 2件: Vfend; VORICONAZOLE1件: D00578 --2件: 60, 299
54 Vorinostat 1件: Vorinostat1件: D06320 11件: HDAC1,
HDAC10,
HDAC11,
HDAC2,
HDAC3,
HDAC4,
HDAC5,
HDAC6,
HDAC7,
HDAC8,
HDAC9 💬
17件: Alcoholism, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Cell cycle, Chronic myeloid leukemia, Epstein-Barr virus infection, Human papillomavirus infection, Huntington disease, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, Notch signaling pathway, Pathways in cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis 💬3件: 19, 75, 96
55 Vortioxetine 1件: Vortioxetine1件: D10184 7件: HTR1A,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E,
SLC6A4 💬
5件: Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬1件: 6
56 Vosoritide 1件: Vosoritide1件: D11190 1件: NPR2 💬5件: Metabolic pathways, Oxytocin signaling pathway, Purine metabolism, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 276
57 VX-659 1件: VX-659---1件: 299
58 VX-702 1件: VX-702---1件: 46