Drug Description in Trials / DrugBank / KEGG DRUG


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No. KEGG DRUG DrugBank 薬物名(臨床試験情報から抽出) KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Niacinamide 💬 1件: Nicotinamide3件: Multivitamin; Niacinamide; NICOTINAMIDE; --10件: 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
2 Niacin 💬 1件: Niacin2件: Niacin; Nicotinic acid; --3件: 6, 78, 79 💬
3 Nitric oxide 💬 1件: Nitric Oxide3件: INOmax; Nitric Oxide; Nitrosyl; --7件: 85, 86, 88, 210, 251, 294, 299 💬
4 Noradrenaline 💬 1件: Norepinephrine2件: Norepinephrine; Norepinephrine Bitartrate; 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬
14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 22, 296 💬
5 Nitrogen 💬 1件: Nitrogen1件: Nitrogen; --5件: 5, 6, 17, 211, 299 💬
6 Nitrous oxide 💬 1件: Nitrous oxide2件: MEOPA; Nitrous Oxide; --2件: 34, 149 💬
7 Naproxen 💬 1件: Naproxen5件: Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid; 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 13, 46, 107, 271 💬
8 Norethindrone 💬 1件: Norethisterone3件: Norethindrone; Ortho-novum; Ortho-Novum 777; 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬4件: 13, 46, 49, 299 💬
9 Nadolol 💬 1件: Nadolol1件: Nadolol; 2件: ADRB1,
ADRB2 💬
11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6 💬
10 Nevirapine 💬 1件: Nevirapine1件: Nevirapine; --1件: 265 💬
11 Niclosamide 💬 1件: Niclosamide1件: Niclosamide; --2件: 46, 97 💬
12 Nifedipine 💬 1件: Nifedipine1件: Nifedipine; 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 50, 81 💬
13 Nitrofurantoin 💬 1件: Nitrofurantoin1件: Nitrofurantoin; --1件: 13 💬
14 Nitroglycerin 💬 1件: Nitroglycerin2件: Nitroglycerin; Nitroglycerine; --2件: 46, 51 💬
15 Nifurtimox 💬 1件: Nifurtimox1件: Nifurtimox; --1件: 65 💬
16 Nandrolone decanoate 💬 1件: Nandrolone decanoate1件: Nandrolone Decanoate; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 60, 85 💬
17 Nimesulide 💬 1件: Nimesulide1件: Nimesulide; 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 46 💬
18 Nilvadipine 💬 1件: Nilvadipine1件: Nilvadipine; 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 90 💬
19 Nitric acid 💬 1件: Nitrate1件: Nitrate; --4件: 58, 67, 113, 299 💬
20 Nitazoxanide 💬 1件: Nitazoxanide1件: Nitazoxanide; --3件: 46, 96, 97 💬
21 Nicotine 💬 1件: Nicotine2件: Nicotine; Nicotine gum; 16件: CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬
8件: Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬3件: 6, 13, 84 💬
22 Nabilone 💬 1件: Nabilone1件: NABILONE; 2件: CNR1,
CNR2 💬
4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬3件: 6, 13, 127 💬
23 Nalmefene 💬 1件: Nalmefene1件: Nalmefene; 3件: OPRD1,
OPRK1,
OPRM1 💬
5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 6 💬
24 Naltrexone 💬 1件: Naltrexone2件: Naltrexone; Naltrexone hydrochloride; 3件: OPRD1,
OPRK1,
OPRM1 💬
5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬12件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
25 Nebivolol 💬 1件: Nebivolol1件: Nebivolol; 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 17, 85, 113, 167 💬
26 Nesiritide 💬 1件: Nesiritide0件: 1件: NPR1 💬10件: Aldosterone synthesis and secretion, Metabolic pathways, Oxytocin signaling pathway, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬-
27 Nitisinone 💬 1件: Nitisinone2件: Nitisinone; Orfadin; 1件: HPD 💬5件: Biosynthesis of cofactors, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis 💬3件: 6, 164, 241 💬
28 Norgestimate 💬 1件: Norgestimate1件: Norgestimate; 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 299 💬
29 Natalizumab 💬 1件: Natalizumab2件: Natalizumab; Tysabri; 1件: ITGA4 💬14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬6件: 13, 15, 25, 46, 63, 96 💬
30 Nomegestrol 💬 1件: Nomegestrol1件: Nomegestrol; 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13 💬
31 Nalbuphine 💬 1件: Nalbuphine2件: Nalbuphine; NALBUPHINE HYDROCHLORIDE; 3件: OPRD1,
OPRK1,
OPRM1 💬
5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 85 💬
32 Naloxone 💬 1件: Naloxone2件: Naloxone; NALOXONE HYDROCHLORIDE; 3件: OPRD1,
OPRK1,
OPRM1 💬
5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 6, 226 💬
33 Nandrolone 💬 1件: Nandrolone1件: Nandrolone; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 60, 85 💬
34 Nelfinavir 💬 1件: Nelfinavir1件: Nelfinavir; --3件: 49, 265, 331 💬
35 Neomycin 💬 1件: Neomycin1件: Neomycin; --3件: 96, 97, 296 💬
36 Nicardipine 💬 1件: Nicardipine1件: Nicardipine; 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 70, 86 💬
37 Nomegestrol acetate 💬 1件: Nomegestrol acetate1件: Nomegestrol acetate; 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13 💬
38 Nortriptyline 💬 1件: Nortriptyline2件: Nortriptyline; Nortriptyline hydrochloride; 2件: SLC6A2,
SLC6A4 💬
2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 226 💬
39 Neratinib 💬 1件: Neratinib1件: Neratinib; 3件: EGFR,
ERBB2,
ERBB4 💬
51件: Adherens junction, Amyotrophic lateral sclerosis, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬1件: 34 💬
40 Nilotinib 💬 1件: Nilotinib2件: Nilotinib; Tasigna; 4件: ABL1,
KIT,
PDGFRA,
PDGFRB 💬
33件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬5件: 6, 8, 34, 51, 86 💬
41 Nabiximols 💬 1件: Nabiximols1件: Nabiximols; --1件: 13 💬
42 Nelotanserin 💬 1件: Nelotanserin1件: Nelotanserin; 1件: HTR2A 💬5件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 6 💬
43 Nivolumab 💬 1件: Nivolumab1件: Nivolumab; 1件: PDCD1 💬3件: Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
44 Nintedanib 💬 1件: Nintedanib2件: Nintedanib; Ofev; 8件: FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬
34件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬5件: 51, 85, 89, 227, 228 💬
45 Nusinersen 💬 1件: Nusinersen2件: NUSINERSEN; Spinraza; 1件: SMN2 💬1件: 💬1件: 3 💬
46 Neflamapimod 💬 1件: Neflamapimod1件: Neflamapimod; 4件: MAPK11,
MAPK12,
MAPK13,
MAPK14 💬
62件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬1件: 8 💬
47 Nemolizumab 💬 1件: Nemolizumab1件: Nemolizumab; 1件: IL31RA 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬1件: 51 💬
48 Nevanimibe 💬 1件: Nevanimibe1件: Nevanimibe; --2件: 75, 81 💬
49 Nomacopan 💬 1件: Nomacopan2件: COVERSIN; NOMACOPAN; 1件: C5 💬11件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬3件: 62, 109, 162 💬
50 Narsoplimab 💬 1件: Narsoplimab2件: MASP-2 antibody; Narsoplimab; 1件: MASP2 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬4件: 64, 66, 109, 222 💬
51 Nipocalimab 💬 1件: Nipocalimab1件: Nipocalimab; 1件: FCGRT 💬1件: 💬6件: 11, 14, 46, 49, 53, 61 💬