Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 GABBR1 💬 7件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206 💬
2 OPRD1 💬 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Naltrexone 💬 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
3 OPRK1 💬 1件: Neuroactive ligand-receptor interaction Naltrexone 💬 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
4 OPRM1 💬 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction Naltrexone 💬 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
5 PGR 💬 5件: Oocyte meiosis, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Chemical carcinogenesis - receptor activation, Breast cancer Ulipristal 💬 Ulipristal 1件: 10 💬
6 SCN1A 💬 1件: Dopaminergic synapse Mexiletine 💬 Mexiletine 5件: 1, 2, 10, 113, 114 💬
7 SCN2A 💬 1件: Taste transduction Mexiletine 💬 Mexiletine 5件: 1, 2, 10, 113, 114 💬
8 SCN3A 💬 1件: Taste transduction Mexiletine 💬 Mexiletine 5件: 1, 2, 10, 113, 114 💬
9 SCN5A 💬 1件: Adrenergic signaling in cardiomyocytes Mexiletine 💬 Mexiletine 5件: 1, 2, 10, 113, 114 💬
10 SCN9A 💬 1件: Taste transduction Mexiletine 💬 Mexiletine 5件: 1, 2, 10, 113, 114 💬
11 GABBR2 💬 7件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206 💬