Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00514 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
2 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01205 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
3 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00514 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
4 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01205 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
5 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00514 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
6 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01205 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
7 ACE 6件: Renin-angiotensin system 💬, Renin secretion 💬, Chagas disease 💬, Coronavirus disease - COVID-19 💬, Hypertrophic cardiomyopathy 💬, Diabetic cardiomyopathy 💬 D00251 Captopril 8件: 6, 17, 46, 86, 96, 97, 107, 271
8 HTR3C 2件: Serotonergic synapse 💬, Taste transduction 💬 D00456 Ondansetron 4件: 6, 97, 107, 231
9 HTR3C 2件: Serotonergic synapse 💬, Taste transduction 💬 D00678 Ondansetron 4件: 6, 97, 107, 231
10 DHFR 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D00142 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
11 DHFR 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D02115 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
12 DHODH 3件: Pyrimidine metabolism 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬 D00749 Leflunomide 12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
13 DHFR2 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D00142 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
14 DHFR2 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D02115 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
15 HTR3D 2件: Serotonergic synapse 💬, Taste transduction 💬 D00456 Ondansetron 4件: 6, 97, 107, 231
16 HTR3D 2件: Serotonergic synapse 💬, Taste transduction 💬 D00678 Ondansetron 4件: 6, 97, 107, 231
17 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D00942 Risedronic acid 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274
18 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D03234 Risedronic acid 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274
19 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D08484 Risedronic acid 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274
20 GHR 5件: Cytokine-cytokine receptor interaction 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Growth hormone synthesis, secretion and action 💬 D02691 Somatotropin 23件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
21 HTR3E 2件: Serotonergic synapse 💬, Taste transduction 💬 D00456 Ondansetron 4件: 6, 97, 107, 231
22 HTR3E 2件: Serotonergic synapse 💬, Taste transduction 💬 D00678 Ondansetron 4件: 6, 97, 107, 231
23 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00385 Triamcinolone 4件: 107, 162, 226, 298
24 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00472 Prednisolone 11件: 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
25 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00980 Prednisolone 11件: 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
26 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00981 Prednisolone 11件: 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
27 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00982 Prednisolone 11件: 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
28 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00983 Triamcinolone 4件: 107, 162, 226, 298
29 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00984 Triamcinolone 4件: 107, 162, 226, 298
30 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00985 Triamcinolone 4件: 107, 162, 226, 298
31 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01239 Prednisolone 11件: 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
32 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01998 Prednisolone 11件: 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
33 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02156 Prednisolone 11件: 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
34 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D03301 Prednisolone 11件: 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
35 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D06216 Triamcinolone 4件: 107, 162, 226, 298
36 HRH2 3件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gastric acid secretion 💬 D00318 Famotidine 7件: 6, 46, 61, 86, 98, 107, 300
37 HTR3A 2件: Serotonergic synapse 💬, Taste transduction 💬 D00456 Ondansetron 4件: 6, 97, 107, 231
38 HTR3A 2件: Serotonergic synapse 💬, Taste transduction 💬 D00678 Ondansetron 4件: 6, 97, 107, 231
39 IFNG 32件: Proteasome 💬, Cytokine-cytokine receptor interaction 💬, HIF-1 signaling pathway 💬, Necroptosis 💬, TGF-beta signaling pathway 💬, Osteoclast differentiation 💬, Antigen processing and presentation 💬, JAK-STAT signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, IL-17 signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, Type I diabetes mellitus 💬, Leishmaniasis 💬, Chagas disease 💬, African trypanosomiasis 💬, Malaria 💬, Toxoplasmosis 💬, Amoebiasis 💬, Tuberculosis 💬, Hepatitis C 💬, Influenza A 💬, Herpes simplex virus 1 infection 💬, Pathways in cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Inflammatory bowel disease 💬, Systemic lupus erythematosus 💬, Rheumatoid arthritis 💬, Allograft rejection 💬, Graft-versus-host disease 💬, Fluid shear stress and atherosclerosis 💬 D11120 Emapalumab 2件: 49, 107
40 IL1A 21件: MAPK signaling pathway 💬, Cytokine-cytokine receptor interaction 💬, Necroptosis 💬, Cellular senescence 💬, Osteoclast differentiation 💬, Hematopoietic cell lineage 💬, Non-alcoholic fatty liver disease 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Type I diabetes mellitus 💬, Alzheimer disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pertussis 💬, Leishmaniasis 💬, Tuberculosis 💬, Measles 💬, Influenza A 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬, Graft-versus-host disease 💬, Fluid shear stress and atherosclerosis 💬 D06635 Rilonacept 4件: 51, 106, 107, 266
41 IL1B 44件: Antifolate resistance 💬, MAPK signaling pathway 💬, Cytokine-cytokine receptor interaction 💬, NF-kappa B signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, Toll-like receptor signaling pathway 💬, NOD-like receptor signaling pathway 💬, Cytosolic DNA-sensing pathway 💬, C-type lectin receptor signaling pathway 💬, Hematopoietic cell lineage 💬, IL-17 signaling pathway 💬, Th17 cell differentiation 💬, TNF signaling pathway 💬, Inflammatory mediator regulation of TRP channels 💬, Non-alcoholic fatty liver disease 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Alcoholic liver disease 💬, Type I diabetes mellitus 💬, Alzheimer disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Salmonella infection 💬, Pertussis 💬, Legionellosis 💬, Yersinia infection 💬, Leishmaniasis 💬, Chagas disease 💬, African trypanosomiasis 💬, Malaria 💬, Amoebiasis 💬, Tuberculosis 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Herpes simplex virus 1 infection 💬, Coronavirus disease - COVID-19 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬, Graft-versus-host disease 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D06635 Rilonacept 4件: 51, 106, 107, 266
42 IL1B 44件: Antifolate resistance 💬, MAPK signaling pathway 💬, Cytokine-cytokine receptor interaction 💬, NF-kappa B signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, Toll-like receptor signaling pathway 💬, NOD-like receptor signaling pathway 💬, Cytosolic DNA-sensing pathway 💬, C-type lectin receptor signaling pathway 💬, Hematopoietic cell lineage 💬, IL-17 signaling pathway 💬, Th17 cell differentiation 💬, TNF signaling pathway 💬, Inflammatory mediator regulation of TRP channels 💬, Non-alcoholic fatty liver disease 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Alcoholic liver disease 💬, Type I diabetes mellitus 💬, Alzheimer disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Salmonella infection 💬, Pertussis 💬, Legionellosis 💬, Yersinia infection 💬, Leishmaniasis 💬, Chagas disease 💬, African trypanosomiasis 💬, Malaria 💬, Amoebiasis 💬, Tuberculosis 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Herpes simplex virus 1 infection 💬, Coronavirus disease - COVID-19 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬, Graft-versus-host disease 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D09315 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
43 IL1R1 13件: MAPK signaling pathway 💬, Cytokine-cytokine receptor interaction 💬, NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Hematopoietic cell lineage 💬, Th17 cell differentiation 💬, Inflammatory mediator regulation of TRP channels 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Amoebiasis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Fluid shear stress and atherosclerosis 💬 D02934 Anakinra 19件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
44 IL2RA 11件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Measles 💬, Human T-cell leukemia virus 1 infection 💬, Pathways in cancer 💬 D03639 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284
45 IL6R 12件: EGFR tyrosine kinase inhibitor resistance 💬, Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, HIF-1 signaling pathway 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Th17 cell differentiation 💬, Non-alcoholic fatty liver disease 💬, Human cytomegalovirus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬 D02596 Tocilizumab 21件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
46 IL6R 12件: EGFR tyrosine kinase inhibitor resistance 💬, Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, HIF-1 signaling pathway 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Th17 cell differentiation 💬, Non-alcoholic fatty liver disease 💬, Human cytomegalovirus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬 D10161 Sarilumab 5件: 41, 46, 84, 107, 271
47 IL17A 6件: Cytokine-cytokine receptor interaction 💬, IL-17 signaling pathway 💬, Th17 cell differentiation 💬, Alcoholic liver disease 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬 D09967 Secukinumab 8件: 13, 37, 41, 46, 107, 160, 269, 271
48 IL17A 6件: Cytokine-cytokine receptor interaction 💬, IL-17 signaling pathway 💬, Th17 cell differentiation 💬, Alcoholic liver disease 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬 D10071 Ixekizumab 6件: 36, 37, 107, 162, 269, 271
49 JAK1 27件: EGFR tyrosine kinase inhibitor resistance 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, Signaling pathways regulating pluripotency of stem cells 💬, NOD-like receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Leishmaniasis 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis C 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human papillomavirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Viral carcinogenesis 💬, Pancreatic cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
50 JAK1 27件: EGFR tyrosine kinase inhibitor resistance 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, Signaling pathways regulating pluripotency of stem cells 💬, NOD-like receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Leishmaniasis 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis C 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human papillomavirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Viral carcinogenesis 💬, Pancreatic cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 D10308 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
51 JAK1 27件: EGFR tyrosine kinase inhibitor resistance 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, Signaling pathways regulating pluripotency of stem cells 💬, NOD-like receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Leishmaniasis 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis C 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human papillomavirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Viral carcinogenesis 💬, Pancreatic cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 D10994 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271
52 JAK2 24件: EGFR tyrosine kinase inhibitor resistance 💬, Chemokine signaling pathway 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Signaling pathways regulating pluripotency of stem cells 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Cholinergic synapse 💬, Prolactin signaling pathway 💬, Adipocytokine signaling pathway 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Growth hormone synthesis, secretion and action 💬, Leishmaniasis 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis B 💬, Influenza A 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
53 JAK2 24件: EGFR tyrosine kinase inhibitor resistance 💬, Chemokine signaling pathway 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Signaling pathways regulating pluripotency of stem cells 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Cholinergic synapse 💬, Prolactin signaling pathway 💬, Adipocytokine signaling pathway 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Growth hormone synthesis, secretion and action 💬, Leishmaniasis 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis B 💬, Influenza A 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D10308 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
54 JAK3 15件: Chemokine signaling pathway 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Signaling pathways regulating pluripotency of stem cells 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Hepatitis B 💬, Measles 💬, Human T-cell leukemia virus 1 infection 💬, Epstein-Barr virus infection 💬, Pathways in cancer 💬, Viral carcinogenesis 💬, Non-small cell lung cancer 💬, Primary immunodeficiency 💬 D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
55 LTA 7件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, NF-kappa B signaling pathway 💬, TNF signaling pathway 💬, Type I diabetes mellitus 💬, Human T-cell leukemia virus 1 infection 💬, Herpes simplex virus 1 infection 💬 D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
56 SERPINC1 1件: Complement and coagulation cascades 💬 D07510 Heparin 7件: 107, 224, 226, 280, 299, 316, 317
57 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D01984 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
58 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D04056 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
59 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D07917 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
60 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D09339 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
61 ATP4B 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D01984 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
62 ATP4B 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D04056 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
63 ATP4B 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D07917 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
64 ATP4B 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D09339 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
65 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271
66 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271
67 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271
68 PDE4D 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271
69 PPP3CA 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
70 PPP3CB 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
71 PPP3CC 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
72 PPP3R1 32件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
73 PPP3R2 32件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
74 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D00118 Naproxen 4件: 13, 46, 107, 271
75 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D00126 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
76 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D01122 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
77 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D04490 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
78 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D06606 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
79 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00118 Naproxen 4件: 13, 46, 107, 271
80 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00126 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
81 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00567 Celecoxib 10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
82 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D01122 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
83 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D04490 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
84 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D06606 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
85 SCN1A 1件: Dopaminergic synapse 💬 D00358 Lidocaine 5件: 107, 168, 226, 231, 256
86 SCN1A 1件: Dopaminergic synapse 💬 D02086 Lidocaine 5件: 107, 168, 226, 231, 256
87 SCN1A 1件: Dopaminergic synapse 💬