Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 SIGMAR1 💬 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
2 SV2C 💬 1件: ECM-receptor interaction Padsevonil 💬 Padsevonil 1件: 149 💬
3 GABBR1 💬 7件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206 💬
4 HTR1D 💬 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
5 HTR2A 💬 5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
6 HTR2C 💬 5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
7 SCN3A 💬 1件: Taste transduction Lacosamide 💬 Lacosamide 4件: 2, 46, 149, 298 💬
8 SCN9A 💬 1件: Taste transduction Lacosamide 💬 Lacosamide 4件: 2, 46, 149, 298 💬
9 SLC6A4 💬 2件: Synaptic vesicle cycle, Serotonergic synapse Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
10 SNAP25 💬 2件: Synaptic vesicle cycle, Insulin secretion Botulinum toxin type A 💬 Botulinum toxin type A 14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
11 CACNA1I 💬 7件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Flunarizine 💬 Flunarizine 1件: 149 💬
12 CACNA1H 💬 7件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Flunarizine 💬 Flunarizine 1件: 149 💬
13 CACNA1G 💬 8件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Flunarizine 💬 Flunarizine 1件: 149 💬
14 GABBR2 💬 7件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206 💬
15 SV2B 💬 1件: ECM-receptor interaction Padsevonil 💬 Padsevonil 1件: 149 💬
16 SV2A 💬 1件: ECM-receptor interaction Brivaracetam 💬 Brivaracetam 2件: 149, 309 💬
17 SV2A 💬 1件: ECM-receptor interaction Padsevonil 💬 Padsevonil 1件: 149 💬