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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
ADRB1
💬
1. ADRB1
×
Name
Full Name
ADRB1
adrenoceptor beta 1
11件:
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Gap junction
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Salivary secretion
,
Chemical carcinogenesis - receptor activation
,
Dilated cardiomyopathy
11件:
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive liga
...
Celiprolol
Celiprolol
💬
1. ADRB1
×
Name
Other Names
Celiprolol
Celiprolol (INN)
Celiprolol PCH (TN)
セリプロロール
Celiprolol
1件:
168
168
💬
1. ADRB1
×
告示番号
日本語名
英語名
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
2
AGTR1
💬
2. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
16件:
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
16件:
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Irbesartan
Irbesartan
💬
2. AGTR1
×
Name
Other Names
Irbesartan
Irbesartan (JP18/USP/INN)
Avapro (TN)
イルベサルタン
アバプロ
イルベタン
Irbesartan
4件:
66
66
,
167
,
168
,
222
💬
2. AGTR1
×
告示番号
日本語名
英語名
66
IgA腎症
IgA nephropathy
167
マルファン症候群
Marfan syndrome
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
3
GHR
💬
3. GHR
×
Name
Full Name
GHR
growth hormone receptor
5件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Neuroactive ligand-receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Growth hormone synthesis, secretion and action
5件:
Cytokine-cytokine receptor interaction
,
Neuroactive ligand-receptor interaction
,
PI3K-Akt signal
...
Mecasermin
Mecasermin
💬
3. GHR
×
Name
Other Names
Mecasermin
Mecasermin (USAN/INN)
Mecasermin (genetical recombination) (JAN)
Increlex (TN)
Myotrophin (TN)
メカセルミン
ソマゾン
Mecasermin
6件:
65
65
,
78
,
96
,
168
,
265
,
299
💬
3. GHR
×
告示番号
日本語名
英語名
65
原発性免疫不全症候群
Primary immunodeficiency
78
下垂体前葉機能低下症
Hypopituitarism
96
クローン病;回腸末端炎
Crohn disease
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
265
脂肪萎縮症
Lipodystrophy
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
4
IGF1R
💬
4. IGF1R
×
Name
Full Name
IGF1R
insulin like growth factor 1 receptor
29件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Oocyte meiosis
,
Autophagy - animal
,
Endocytosis
,
mTOR signaling pathway
,
PI3K-Akt signaling pathway
,
AMPK signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Focal adhesion
,
Adherens junction
,
Signaling pathways regulating pluripotency of stem cells
,
Long-term depression
,
Ovarian steroidogenesis
,
Progesterone-mediated oocyte maturation
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Proteoglycans in cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Breast cancer
,
Hepatocellular carcinoma
29件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
Ras si
...
Mecasermin
Mecasermin
💬
4. IGF1R
×
Name
Other Names
Mecasermin
Mecasermin (USAN/INN)
Mecasermin (genetical recombination) (JAN)
Increlex (TN)
Myotrophin (TN)
メカセルミン
ソマゾン
Mecasermin
6件:
65
65
,
78
,
96
,
168
,
265
,
299
💬
4. IGF1R
×
告示番号
日本語名
英語名
65
原発性免疫不全症候群
Primary immunodeficiency
78
下垂体前葉機能低下症
Hypopituitarism
96
クローン病;回腸末端炎
Crohn disease
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
265
脂肪萎縮症
Lipodystrophy
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
5
OXTR
💬
5. OXTR
×
Name
Full Name
OXTR
oxytocin receptor
4件:
Calcium signaling pathway
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Oxytocin signaling pathway
4件:
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Oxyt
...
Oxytocin
Oxytocin
💬
5. OXTR
×
Name
Other Names
Oxytocin
Oxytocin (JP18/USP/INN)
Oxytocin (TN)
Pitocin (TN)
Syntocinon (TN)
オキシトシン
アトニン
Oxytocin
7件:
6
6
,
72
,
127
,
168
,
193
,
206
,
226
💬
5. OXTR
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
72
下垂体性ADH分泌異常症
Pituitary ADH secretion disorder
127
前頭側頭葉変性症
Frontotemporal lobar degeneration
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
193
プラダー・ウィリ症候群
Prader-Willi syndrome
206
脆弱X症候群
Fragile X syndrome
226
間質性膀胱炎(ハンナ型)
Interstitial cystitis with Hunners ulcer
6
PRKCB
💬
6. PRKCB
×
Name
Full Name
PRKCB
protein kinase C beta
71件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
Chemokine signaling pathway
,
NF-kappa B signaling pathway
,
HIF-1 signaling pathway
,
Phosphatidylinositol signaling system
,
Sphingolipid signaling pathway
,
mTOR signaling pathway
,
Vascular smooth muscle contraction
,
Wnt signaling pathway
,
VEGF signaling pathway
,
Focal adhesion
,
Gap junction
,
Neutrophil extracellular trap formation
,
Natural killer cell mediated cytotoxicity
,
B cell receptor signaling pathway
,
Fc gamma R-mediated phagocytosis
,
Leukocyte transendothelial migration
,
Circadian entrainment
,
Long-term potentiation
,
Retrograde endocannabinoid signaling
,
Glutamatergic synapse
,
Cholinergic synapse
,
Serotonergic synapse
,
GABAergic synapse
,
Dopaminergic synapse
,
Long-term depression
,
Inflammatory mediator regulation of TRP channels
,
Insulin secretion
,
GnRH signaling pathway
,
Melanogenesis
,
Thyroid hormone synthesis
,
Thyroid hormone signaling pathway
,
Oxytocin signaling pathway
,
Aldosterone synthesis and secretion
,
Parathyroid hormone synthesis, secretion and action
,
GnRH secretion
,
Insulin resistance
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Aldosterone-regulated sodium reabsorption
,
Endocrine and other factor-regulated calcium reabsorption
,
Salivary secretion
,
Gastric acid secretion
,
Pancreatic secretion
,
Carbohydrate digestion and absorption
,
Spinocerebellar ataxia
,
Pathways of neurodegeneration - multiple diseases
,
Amphetamine addiction
,
Morphine addiction
,
Leishmaniasis
,
African trypanosomiasis
,
Amoebiasis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Influenza A
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Glioma
,
Non-small cell lung cancer
,
Hepatocellular carcinoma
,
Choline metabolism in cancer
,
Diabetic cardiomyopathy
71件:
EGFR tyrosine kinase inhibitor resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras
...
Enzastaurin
Enzastaurin
💬
6. PRKCB
×
Name
Other Names
Enzastaurin
Enzastaurin (USAN/INN)
エンザスタウリン
Enzastaurin
1件:
168
168
💬
6. PRKCB
×
告示番号
日本語名
英語名
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
7
SCN1A
💬
7. SCN1A
×
Name
Full Name
SCN1A
sodium voltage-gated channel alpha subunit 1
1件:
Dopaminergic synapse
Dopaminergic synapse
Lidocaine
Lidocaine
💬
7. SCN1A
×
Name
Other Names
Lidocaine
Lidocaine (JP18/USP/INN)
Dentipatch (TN)
Xylocaine (TN)
LIDODERM
ZTLIDO
LIDOCAINE 5%
LIDOCAINE PATCH
LMR PLUS
リドカイン
ペンレス
キシロカイン
Lidocaine
13件:
6
6
,
13
,
22
,
34
,
46
,
51
,
70
,
84
,
86
,
107
,
168
,
226
,
256
💬
7. SCN1A
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
22
もやもや病;ウィリス動脈輪閉塞症
Moyamoya disease
34
神経線維腫症
Neurofibromatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
51
全身性強皮症
Scleroderma
70
広範脊柱管狭窄症
Spinal stenosis
84
サルコイドーシス
Sarcoidosis
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
107
若年性特発性関節炎
Juvenile idiopathic arthritis
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
226
間質性膀胱炎(ハンナ型)
Interstitial cystitis with Hunners ulcer
256
筋型糖原病
Muscle glycogenosis
8
SCN1A
💬
8. SCN1A
×
Name
Full Name
SCN1A
sodium voltage-gated channel alpha subunit 1
1件:
Dopaminergic synapse
Dopaminergic synapse
Bupivacaine
Bupivacaine
💬
8. SCN1A
×
Name
Other Names
Bupivacaine
Bupivacaine (USAN/INN)
Bucaine (TN)
Exparel (TN)
POSIMIR
ブピバカイン
Bupivacaine
8件:
46
46
,
51
,
53
,
70
,
96
,
168
,
226
,
298
💬
8. SCN1A
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
51
全身性強皮症
Scleroderma
53
シェーグレン症候群
Sjogren syndrome
70
広範脊柱管狭窄症
Spinal stenosis
96
クローン病;回腸末端炎
Crohn disease
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
226
間質性膀胱炎(ハンナ型)
Interstitial cystitis with Hunners ulcer
298
遺伝性膵炎
Hereditary pancreatitis
9
SCN1A
💬
9. SCN1A
×
Name
Full Name
SCN1A
sodium voltage-gated channel alpha subunit 1
1件:
Dopaminergic synapse
Dopaminergic synapse
Lidocaine hydrochloride monohydrate
Lidocaine hydrochloride monohydrate
💬
9. SCN1A
×
Name
Other Names
Lidocaine hydrochloride monohydrate
Lidocaine hydrochloride monohydrate
Lidocaine (TN)
Zingo (TN)
1% LIDOCAINE HCI
2% LIDOCAINE HCI
LIDENZAL 1%
LIDENZAL 2%
LIDOCAINE HCI
LIDOCAINE HCL
LIDOCAINE HYDROCHLORIDE
NA
PRELIDOPINE PRE-OPERATIVE SYSTEM
リドカイン塩酸塩水和物
キシロカイン
Lidocaine
13件:
6
6
,
13
,
22
,
34
,
46
,
51
,
70
,
84
,
86
,
107
,
168
,
226
,
256
💬
9. SCN1A
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
22
もやもや病;ウィリス動脈輪閉塞症
Moyamoya disease
34
神経線維腫症
Neurofibromatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
51
全身性強皮症
Scleroderma
70
広範脊柱管狭窄症
Spinal stenosis
84
サルコイドーシス
Sarcoidosis
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
107
若年性特発性関節炎
Juvenile idiopathic arthritis
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
226
間質性膀胱炎(ハンナ型)
Interstitial cystitis with Hunners ulcer
256
筋型糖原病
Muscle glycogenosis
10
SCN2A
💬
10. SCN2A
×
Name
Full Name
SCN2A
sodium voltage-gated channel alpha subunit 2
1件:
Taste transduction
Taste transduction
Lidocaine
Lidocaine
💬
10. SCN2A
×
Name
Other Names
Lidocaine
Lidocaine (JP18/USP/INN)
Dentipatch (TN)
Xylocaine (TN)
LIDODERM
ZTLIDO
LIDOCAINE 5%
LIDOCAINE PATCH
LMR PLUS
リドカイン
ペンレス
キシロカイン
Lidocaine
13件:
6
6
,
13
,
22
,
34
,
46
,
51
,
70
,
84
,
86
,
107
,
168
,
226
,
256
💬
10. SCN2A
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
22
もやもや病;ウィリス動脈輪閉塞症
Moyamoya disease
34
神経線維腫症
Neurofibromatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
51
全身性強皮症
Scleroderma
70
広範脊柱管狭窄症
Spinal stenosis
84
サルコイドーシス
Sarcoidosis
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
107
若年性特発性関節炎
Juvenile idiopathic arthritis
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
226
間質性膀胱炎(ハンナ型)
Interstitial cystitis with Hunners ulcer
256
筋型糖原病
Muscle glycogenosis