Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D00646 Tolterodine 2件: 17, 53
2 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D01148 Tolterodine 2件: 17, 53
3 COMT 4件: Steroid hormone biosynthesis 💬, Tyrosine metabolism 💬, Metabolic pathways 💬, Dopaminergic synapse 💬 D00781 Entacapone 2件: 6, 17
4 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D00485 Pseudoephedrine 1件: 17
5 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
6 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D01307 Midodrine 3件: 6, 17, 58
7 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D05648 Pseudoephedrine 1件: 17
8 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D05649 Pseudoephedrine 1件: 17
9 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D08220 Midodrine 3件: 6, 17, 58
10 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D08449 Pseudoephedrine 1件: 17
11 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D00485 Pseudoephedrine 1件: 17
12 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
13 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D01307 Midodrine 3件: 6, 17, 58
14 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D05648 Pseudoephedrine 1件: 17
15 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D05649 Pseudoephedrine 1件: 17
16 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D08220 Midodrine 3件: 6, 17, 58
17 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D08449 Pseudoephedrine 1件: 17
18 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D00485 Pseudoephedrine 1件: 17
19 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
20 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D01307 Midodrine 3件: 6, 17, 58
21 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D05648 Pseudoephedrine 1件: 17
22 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D05649 Pseudoephedrine 1件: 17
23 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D08220 Midodrine 3件: 6, 17, 58
24 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D08449 Pseudoephedrine 1件: 17
25 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00485 Pseudoephedrine 1件: 17
26 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
27 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D05648 Pseudoephedrine 1件: 17
28 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D05649 Pseudoephedrine 1件: 17
29 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D08449 Pseudoephedrine 1件: 17
30 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00485 Pseudoephedrine 1件: 17
31 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
32 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D05648 Pseudoephedrine 1件: 17
33 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D05649 Pseudoephedrine 1件: 17
34 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D08449 Pseudoephedrine 1件: 17
35 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00485 Pseudoephedrine 1件: 17
36 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
37 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D05648 Pseudoephedrine 1件: 17
38 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D05649 Pseudoephedrine 1件: 17
39 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D08449 Pseudoephedrine 1件: 17
40 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D00485 Pseudoephedrine 1件: 17
41 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D00601 Metoprolol 6件: 17, 57, 58, 113, 193, 226
42 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
43 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D02358 Metoprolol 6件: 17, 57, 58, 113, 193, 226
44 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D05011 Metoprolol 6件: 17, 57, 58, 113, 193, 226
45 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D05127 Nebivolol 4件: 17, 85, 113, 167
46 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D05648 Pseudoephedrine 1件: 17
47 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D05649 Pseudoephedrine 1件: 17
48 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D08449 Pseudoephedrine 1件: 17
49 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D00485 Pseudoephedrine 1件: 17
50 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
51 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D05648 Pseudoephedrine 1件: 17
52 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D05649 Pseudoephedrine 1件: 17
53 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D08449 Pseudoephedrine 1件: 17
54 ADRB3 8件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D00485 Pseudoephedrine 1件: 17
55 ADRB3 8件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
56 ADRB3 8件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D05648 Pseudoephedrine 1件: 17
57 ADRB3 8件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D05649 Pseudoephedrine 1件: 17
58 ADRB3 8件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D08449 Pseudoephedrine 1件: 17
59 ACE 6件: Renin-angiotensin system 💬, Renin secretion 💬, Chagas disease 💬, Coronavirus disease - COVID-19 💬, Hypertrophic cardiomyopathy 💬, Diabetic cardiomyopathy 💬 D00251 Captopril 8件: 6, 17, 46, 86, 96, 97, 107, 271
60 DDC 9件: Tyrosine metabolism 💬, Phenylalanine metabolism 💬, Tryptophan metabolism 💬, Metabolic pathways 💬, Serotonergic synapse 💬, Dopaminergic synapse 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Alcoholism 💬 D00558 Carbidopa 9件: 2, 4, 6, 13, 17, 90, 140, 164, 201
61 DRD1 10件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Morphine addiction 💬, Alcoholism 💬 D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
62 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
63 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D01226 Sulpiride 5件: 2, 6, 17, 46, 70
64 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D01745 Domperidone 5件: 6, 13, 17, 51, 230
65 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D07868 Domperidone 5件: 6, 13, 17, 51, 230
66 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D08549 Sulpiride 5件: 2, 6, 17, 46, 70
67 DRD3 2件: Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
68 DRD4 2件: Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
69 DRD5 4件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
70 AGTR1 16件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Phospholipase D signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Apelin signaling pathway 💬, Renin-angiotensin system 💬, Renin secretion 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Cushing syndrome 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Diabetic cardiomyopathy 💬 D00150 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
71 AGTR1 16件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Phospholipase D signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Apelin signaling pathway 💬, Renin-angiotensin system 💬, Renin secretion 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Cushing syndrome 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Diabetic cardiomyopathy 💬 D00357 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
72 AGTR1 16件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Phospholipase D signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Apelin signaling pathway 💬, Renin-angiotensin system 💬, Renin secretion 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Cushing syndrome 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Diabetic cardiomyopathy 💬 D02014 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
73 AGTR1 16件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Phospholipase D signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Apelin signaling pathway 💬, Renin-angiotensin system 💬, Renin secretion 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Cushing syndrome 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Diabetic cardiomyopathy 💬 D08146 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
74 AGTR2 3件: Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Renin-angiotensin system 💬 D00150 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
75 AGTR2 3件: Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Renin-angiotensin system 💬 D02014 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
76 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D01968 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
77 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D06378 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
78 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D06379 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
79 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D08689 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
80 MTOR 51件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, ErbB signaling pathway 💬, HIF-1 signaling pathway 💬, Phospholipase D signaling pathway 💬, Autophagy - other 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Cellular senescence 💬, Apelin signaling pathway 💬, Neutrophil extracellular trap formation 💬, JAK-STAT signaling pathway 💬, Th17 cell differentiation 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Adipocytokine signaling pathway 💬, Type II diabetes mellitus 💬, Insulin resistance 💬, Growth hormone synthesis, secretion and action 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Shigellosis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Human immunodeficiency virus 1 infection 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, MicroRNAs in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Colorectal cancer 💬, Pancreatic cancer 💬, Glioma 💬, Prostate cancer 💬, Acute myeloid leukemia 💬, Breast cancer 💬, Hepatocellular carcinoma 💬, Gastric cancer 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Diabetic cardiomyopathy 💬 D00753 Sirolimus 41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
81 GABRA1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
82 GABRA2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
83 GABRA3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
84 GABRA4 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
85 GABRA5 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
86 GABRA6 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
87 GABRB1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
88 GABRB2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
89 GABRB3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
90 GABRD 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
91 GABRE 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
92 GABRG1 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
93 GABRG2 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
94 GABRG3 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
95 GABRP 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
96 GLP1R 3件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Insulin secretion 💬 D04121 Exenatide 6件: 6, 17, 72, 78, 193, 233
97 GRIA1 14件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Long-term depression 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Nicotine addiction 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
98 GRIA2 15件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Long-term depression 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
99 GRIA3 13件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Long-term depression 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Transcriptional misregulation in cancer 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
100 GRIA4 10件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Huntington disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Nicotine addiction 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
101 GRIK1 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
102 GRIK2 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
103 GRIK3 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
104 GRIK4 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
105 GRIK5 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
106 GRIN1 18件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
107 GRIN2A 19件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬, Systemic lupus erythematosus 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
108 GRIN2B 19件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬, Systemic lupus erythematosus 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
109 GRIN2C 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
110 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬,