Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 CNR1 4件: Rap1 signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Retrograde endocannabinoid signaling 💬 D10915 Cannabidiol 19件: 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
2 CNR2 1件: Neuroactive ligand-receptor interaction 💬 D10915 Cannabidiol 3件: 206, 226, 271
3 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D02268 Ergoloid mesylate 2件: 6, 206
4 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D02268 Ergoloid mesylate 2件: 6, 206
5 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D02268 Ergoloid mesylate 2件: 6, 206
6 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D02268 Ergoloid mesylate 2件: 6, 206
7 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D02268 Ergoloid mesylate 2件: 6, 206
8 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D02268 Ergoloid mesylate 2件: 6, 206
9 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D00426 Risperidone 5件: 8, 156, 179, 187, 206
10 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D01164 Aripiprazole 2件: 6, 206
11 DRD3 2件: Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D01164 Aripiprazole 2件: 6, 206
12 GABBR1 7件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, GABAergic synapse 💬, Taste transduction 💬, Estrogen signaling pathway 💬, GnRH secretion 💬, Morphine addiction 💬 D00241 Baclofen 7件: 2, 10, 13, 18, 65, 149, 206
13 GABBR1 7件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, GABAergic synapse 💬, Taste transduction 💬, Estrogen signaling pathway 💬, GnRH secretion 💬, Morphine addiction 💬 D09791 Arbaclofen 2件: 13, 206
14 GABRA1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
15 GABRA1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
16 GABRA1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
17 GABRA2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
18 GABRA2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
19 GABRA2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
20 GABRA3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
21 GABRA3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
22 GABRA3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
23 GABRA4 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
24 GABRA4 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
25 GABRA4 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
26 GABRA5 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
27 GABRA5 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
28 GABRA5 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
29 GABRA6 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
30 GABRA6 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
31 GABRA6 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
32 GABRB1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
33 GABRB1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
34 GABRB1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
35 GABRB2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
36 GABRB2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
37 GABRB2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
38 GABRB3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
39 GABRB3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
40 GABRB3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
41 GABRD 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
42 GABRD 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
43 GABRD 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
44 GABRE 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
45 GABRE 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
46 GABRE 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
47 GABRG1 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
48 GABRG1 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
49 GABRG1 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
50 GABRG2 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
51 GABRG2 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
52 GABRG2 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
53 GABRG3 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
54 GABRG3 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
55 GABRG3 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
56 GABRP 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
57 GABRP 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
58 GABRP 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
59 GRIA1 14件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Long-term depression 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Nicotine addiction 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
60 GRIA2 15件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Long-term depression 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
61 GRIA3 13件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Long-term depression 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Transcriptional misregulation in cancer 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
62 GRIA4 10件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Huntington disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Nicotine addiction 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
63 GRIK1 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
64 GRIK2 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
65 GRIK3 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
66 GRIK4 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
67 GRIK5 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
68 GRIN1 18件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
69 GRIN1 18件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D02780 Acamprosate 2件: 6, 206
70 GRIN1 18件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D07058 Acamprosate 2件: 6, 206
71 GRIN2A 19件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬, Systemic lupus erythematosus 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
72 GRIN2A 19件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬, Systemic lupus erythematosus 💬 D02780 Acamprosate 2件: 6, 206
73 GRIN2A 19件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬, Systemic lupus erythematosus 💬 D07058 Acamprosate 2件: 6, 206
74 GRIN2B 19件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬, Systemic lupus erythematosus 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
75 GRIN2B 19件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬, Systemic lupus erythematosus 💬 D02780 Acamprosate 2件: 6, 206
76 GRIN2B 19件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬, Systemic lupus erythematosus 💬 D07058 Acamprosate 2件: 6, 206
77 GRIN2C 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
78 GRIN2C 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D02780 Acamprosate 2件: 6, 206
79 GRIN2C 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D07058 Acamprosate 2件: 6, 206
80 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
81 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D02780 Acamprosate 2件: 6, 206
82 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D07058 Acamprosate 2件: 6, 206
83 HMGCR 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, AMPK signaling pathway 💬, Bile secretion 💬 D00359 Lovastatin 11件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
84 HTR1A 4件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Serotonergic synapse 💬, Taste transduction 💬 D01164 Aripiprazole 2件: 6, 206
85 HTR2A 5件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Serotonergic synapse 💬, Inflammatory mediator regulation of TRP channels 💬 D00426 Risperidone 5件: 8, 156, 179, 187, 206
86 HTR2A 5件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Serotonergic synapse 💬, Inflammatory mediator regulation of TRP channels 💬 D01164 Aripiprazole 2件: 6, 206
87 ACHE 2件: Glycerophospholipid metabolism 💬, Cholinergic synapse 💬 D00670 Donepezil 9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
88 ACHE 2件: Glycerophospholipid metabolism 💬, Cholinergic synapse 💬 D07869 Donepezil 9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
89 OXTR 4件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Oxytocin signaling pathway 💬 D00089 Oxytocin 6件: 6, 72, 127, 193, 206, 226
90 PRKAA1 20件: FoxO signaling pathway 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Apelin signaling pathway 💬, Tight junction 💬, Circadian rhythm 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Adipocytokine signaling pathway 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Alcoholic liver disease 💬, Hypertrophic cardiomyopathy 💬, Fluid shear stress and atherosclerosis 💬 D00944 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
91 PRKAA1 20件: FoxO signaling pathway 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Apelin signaling pathway 💬, Tight junction 💬, Circadian rhythm 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Adipocytokine signaling pathway 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Alcoholic liver disease 💬, Hypertrophic cardiomyopathy 💬, Fluid shear stress and atherosclerosis 💬 D04966 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
92 PRKAA2 20件: FoxO signaling pathway 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Apelin signaling pathway 💬, Tight junction 💬, Circadian rhythm 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Adipocytokine signaling pathway 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Alcoholic liver disease 💬, Hypertrophic cardiomyopathy 💬, Fluid shear stress and atherosclerosis 💬 D00944 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
93 PRKAA2 20件: FoxO signaling pathway 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Apelin signaling pathway 💬, Tight junction 💬, Circadian rhythm 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Adipocytokine signaling pathway 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Alcoholic liver disease 💬, Hypertrophic cardiomyopathy 💬, Fluid shear stress and atherosclerosis 💬 D04966 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
94 GABRQ 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00697 Flumazenil 5件: 6, 13, 17, 18, 206
95 GABRQ 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04282 Gaboxadol 2件: 201, 206
96 GABRQ 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D04300 Ganaxolone 4件: 145, 152, 158, 206
97 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D00120 Sulindac 1件: 206
98 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00120 Sulindac 1件: 206
99 SLC6A2 1件: Synaptic vesicle cycle 💬 D01296 Methylphenidate 1件: 206
100 SLC6A2 1件: Synaptic vesicle cycle 💬 D04999 Methylphenidate 1件: 206
101 SLC6A3 7件: Synaptic vesicle cycle 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Alcoholism 💬 D01296 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206
102 SLC6A3 7件: Synaptic vesicle cycle 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Alcoholism 💬 D04999 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206
103 SLC6A4 2件: Synaptic vesicle cycle 💬, Serotonergic synapse 💬 D00326 Fluoxetine 6件: 13, 17, 78, 86, 179, 206
104 SLC6A4 2件: Synaptic vesicle cycle 💬, Serotonergic synapse 💬 D00823 Fluoxetine 6件: 13, 17, 78, 86, 179, 206
105 SLC6A4 2件: Synaptic vesicle cycle 💬, Serotonergic synapse 💬 D00825 Sertraline 2件: 6, 206
106 SLC6A4 2件: Synaptic vesicle cycle 💬, Serotonergic synapse 💬 D02360 Sertraline 2件: 6, 206
107 GABBR2 7件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, GABAergic synapse 💬, Taste transduction 💬, Estrogen signaling pathway 💬, GnRH secretion 💬, Morphine addiction 💬 D00241 Baclofen 7件: 2, 10, 13, 18, 65, 149, 206
108 GABBR2 7件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, GABAergic synapse 💬, Taste transduction 💬, Estrogen signaling pathway 💬, GnRH secretion 💬, Morphine addiction 💬 D09791 Arbaclofen 2件: 13, 206