Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CA5B 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
2 F8 💬 1件: Complement and coagulation cascades Desmopressin 💬 Desmopressin 6件: 6, 64, 72, 75, 225, 288 💬
3 CA14 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
4 GUCY1A2 💬 11件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Riociguat 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
5 GUCY1A1 💬 11件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Riociguat 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
6 GUCY1B1 💬 11件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Riociguat 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
7 HMGCR 💬 4件: Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Atorvastatin 💬 Atorvastatin 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
8 CA13 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
9 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Spironolactone 💬 Spironolactone 8件: 46, 58, 67, 86, 113, 210, 218, 225 💬
10 ATP4A 💬 4件: Oxidative phosphorylation, Metabolic pathways, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole 14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
11 ATP4B 💬 4件: Oxidative phosphorylation, Metabolic pathways, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole 14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
12 AVPR2 💬 3件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vasopressin-regulated water reabsorption Desmopressin 💬 Desmopressin 6件: 6, 64, 72, 75, 225, 288 💬
13 AVPR2 💬 3件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vasopressin-regulated water reabsorption Tolvaptan 💬 Tolvaptan 4件: 67, 72, 86, 225 💬
14 PRKAA1 💬 20件: FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin 25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
15 PRKAA2 💬 20件: FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin 25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
16 PTGS1 💬 5件: Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬
17 PTGS2 💬 22件: Arachidonic acid metabolism, Metabolic pathways, NF-kappa B signaling pathway, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬
18 SCNN1A 💬 2件: Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride 4件: 13, 67, 225, 299 💬
19 SCNN1B 💬 2件: Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride 4件: 13, 67, 225, 299 💬
20 SCNN1G 💬 2件: Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride 4件: 13, 67, 225, 299 💬
21 SLC12A3 💬 - Hydrochlorothiazide 💬 Hydrochlorothiazide 4件: 13, 67, 225, 235 💬
22 SLC12A3 💬 - Chlorothiazide 💬 Chlorothiazide 1件: 225 💬
23 CA1 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
24 CA2 💬 7件: Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
25 CA3 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
26 CA4 💬 3件: Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
27 CA5A 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
28 CA6 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
29 CA7 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
30 CA8 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
31 CA9 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
32 CA12 💬 2件: Nitrogen metabolism, Metabolic pathways Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
33 PDE5A 💬 3件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway Sildenafil 💬 Sildenafil 17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬