Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
2 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
3 CHRM1 8件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D08441 Propiverine 1件: 226
4 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D08441 Propiverine 1件: 226
5 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D08441 Propiverine 1件: 226
6 CHRM4 3件: Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D08441 Propiverine 1件: 226
7 CHRM5 6件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D08441 Propiverine 1件: 226
8 CNR1 4件: Rap1 signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Retrograde endocannabinoid signaling 💬 D10915 Cannabidiol 19件: 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
9 CNR2 1件: Neuroactive ligand-receptor interaction 💬 D10915 Cannabidiol 2件: 226, 271
10 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00514 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
11 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01205 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
12 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00514 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
13 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01205 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
14 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00514 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
15 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01205 Dexmedetomidine 13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
16 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D00601 Metoprolol 6件: 17, 57, 58, 113, 193, 226
17 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D02358 Metoprolol 6件: 17, 57, 58, 113, 193, 226
18 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D05011 Metoprolol 6件: 17, 57, 58, 113, 193, 226
19 ADRB3 8件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D09535 Mirabegron 4件: 6, 13, 53, 226
20 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D00105 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
21 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01413 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
22 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01617 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
23 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01953 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
24 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04061 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
25 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04063 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
26 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04064 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
27 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04065 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
28 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D00105 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
29 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01413 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
30 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01617 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
31 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01953 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
32 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04061 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
33 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04063 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
34 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04064 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
35 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04065 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
36 FCER1A 4件: Sphingolipid signaling pathway 💬, Phospholipase D signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Asthma 💬 D05251 Omalizumab 7件: 46, 53, 65, 98, 162, 226, 299
37 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
38 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
39 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00385 Triamcinolone 2件: 226, 298
40 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00983 Triamcinolone 2件: 226, 298
41 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00984 Triamcinolone 2件: 226, 298
42 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00985 Triamcinolone 2件: 226, 298
43 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D06216 Triamcinolone 2件: 226, 298
44 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D00752 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
45 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05094 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
46 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05095 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
47 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05096 Mycophenolic acid 36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
48 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D00752 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
49 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05094 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
50 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05095 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
51 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05096 Mycophenolic acid 36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
52 SERPINC1 1件: Complement and coagulation cascades 💬 D07510 Heparin 5件: 226, 280, 299, 316, 317
53 NGF 9件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Cytokine-cytokine receptor interaction 💬, PI3K-Akt signaling pathway 💬, Apoptosis 💬, Neurotrophin signaling pathway 💬, Inflammatory mediator regulation of TRP channels 💬 D09387 Tanezumab 2件: 226, 298
54 OPRD1 3件: cGMP-PKG signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01340 Naloxone 2件: 6, 226
55 OPRD1 3件: cGMP-PKG signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D02095 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
56 OPRD1 3件: cGMP-PKG signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D03783 Oxycodone 7件: 6, 13, 46, 70, 226, 231, 298
57 OPRD1 3件: cGMP-PKG signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D05113 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
58 OPRD1 3件: cGMP-PKG signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D05312 Oxycodone 7件: 6, 13, 46, 70, 226, 231, 298
59 OPRD1 3件: cGMP-PKG signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D05462 Oxycodone 7件: 6, 13, 46, 70, 226, 231, 298
60 OPRD1 3件: cGMP-PKG signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D08249 Naloxone 2件: 6, 226
61 OPRK1 1件: Neuroactive ligand-receptor interaction 💬 D01340 Naloxone 1件: 226
62 OPRK1 1件: Neuroactive ligand-receptor interaction 💬 D02095 Naltrexone 1件: 226
63 OPRK1 1件: Neuroactive ligand-receptor interaction 💬 D03783 Oxycodone 3件: 226, 231, 298
64 OPRK1 1件: Neuroactive ligand-receptor interaction 💬 D05113 Naltrexone 1件: 226
65 OPRK1 1件: Neuroactive ligand-receptor interaction 💬 D05312 Oxycodone 3件: 226, 231, 298
66 OPRK1 1件: Neuroactive ligand-receptor interaction 💬 D05462 Oxycodone 3件: 226, 231, 298
67 OPRK1 1件: Neuroactive ligand-receptor interaction 💬 D08249 Naloxone 1件: 226
68 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D01340 Naloxone 2件: 6, 226
69 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D01355 Tramadol 5件: 46, 70, 78, 226, 271
70 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D02095 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
71 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D03783 Oxycodone 7件: 6, 13, 46, 70, 226, 231, 298
72 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D05113 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
73 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D05312 Oxycodone 7件: 6, 13, 46, 70, 226, 231, 298
74 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D05462 Oxycodone 7件: 6, 13, 46, 70, 226, 231, 298
75 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D08249 Naloxone 2件: 6, 226
76 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D08623 Tramadol 5件: 46, 70, 78, 226, 271
77 OXTR 4件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Oxytocin signaling pathway 💬 D00089 Oxytocin 6件: 6, 72, 127, 193, 206, 226
78 P2RX3 3件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Taste transduction 💬 D11349 Gefapixant 2件: 85, 226
79 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
80 PDE11A 4件: Purine metabolism 💬, Metabolic pathways 💬, Cushing syndrome 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
81 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
82 PDE1A 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
83 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
84 PDE1C 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
85 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
86 PDE2A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Olfactory transduction 💬, Aldosterone synthesis and secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
87 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
88 PDE3A 6件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Renin secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
89 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
90 PDE3B 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Apelin signaling pathway 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Glucagon signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
91 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
92 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
93 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
94 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
95 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
96 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
97 PDE4D 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
98 PDE4D 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
99 PDE7A 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
100 PDE7A 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
101 PDE8A 5件: Purine metabolism 💬, Metabolic pathways 💬, Cortisol synthesis and secretion 💬, Cushing syndrome 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
102 PDE8A 5件: Purine metabolism 💬, Metabolic pathways 💬, Cortisol synthesis and secretion 💬, Cushing syndrome 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
103 PDE1B 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
104 PDE1B 7件: Purine metabolism 💬, Metabolic pathways 💬, Calcium signaling pathway 💬, Olfactory transduction 💬, Taste transduction 💬, Renin secretion 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
105 PPP3CA 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
106 PPP3CA 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
107 PPP3CA 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
108 PPP3CB 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
109 PPP3CB 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
110 PPP3CB 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
111 PPP3CC 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
112 PPP3CC 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: