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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
TUBB3
💬
1. TUBB3
×
Name
Full Name
TUBB3
tubulin beta 3 class III
10件:
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
10件:
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Colchicine
Colchicine
💬
1. TUBB3
×
Name
Other Names
Colchicine
Colchicine (JP18/USP)
Colchicine (TN)
COLCRYS
GLOPERBA
MITIGARE
コルヒチン
Colchicine
7件:
2
2
,
42
,
46
,
56
,
93
,
210
,
266
💬
1. TUBB3
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
42
結節性多発動脈炎
Polyarteritis nodosa
46
悪性関節リウマチ
Malignant rheumatoid arthritis
56
ベーチェット病
Behcet disease
93
原発性胆汁性胆管炎
Primary biliary cholangitis
210
単心室症
Single Ventricle
266
家族性地中海熱
Familial mediterranean fever
2
TUBB4A
💬
2. TUBB4A
×
Name
Full Name
TUBB4A
tubulin beta 4A class IVa
10件:
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
10件:
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Colchicine
Colchicine
💬
2. TUBB4A
×
Name
Other Names
Colchicine
Colchicine (JP18/USP)
Colchicine (TN)
COLCRYS
GLOPERBA
MITIGARE
コルヒチン
Colchicine
7件:
2
2
,
42
,
46
,
56
,
93
,
210
,
266
💬
2. TUBB4A
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
42
結節性多発動脈炎
Polyarteritis nodosa
46
悪性関節リウマチ
Malignant rheumatoid arthritis
56
ベーチェット病
Behcet disease
93
原発性胆汁性胆管炎
Primary biliary cholangitis
210
単心室症
Single Ventricle
266
家族性地中海熱
Familial mediterranean fever
3
TUBB4B
💬
3. TUBB4B
×
Name
Full Name
TUBB4B
tubulin beta 4B class IVb
10件:
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
10件:
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Colchicine
Colchicine
💬
3. TUBB4B
×
Name
Other Names
Colchicine
Colchicine (JP18/USP)
Colchicine (TN)
COLCRYS
GLOPERBA
MITIGARE
コルヒチン
Colchicine
7件:
2
2
,
42
,
46
,
56
,
93
,
210
,
266
💬
3. TUBB4B
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
42
結節性多発動脈炎
Polyarteritis nodosa
46
悪性関節リウマチ
Malignant rheumatoid arthritis
56
ベーチェット病
Behcet disease
93
原発性胆汁性胆管炎
Primary biliary cholangitis
210
単心室症
Single Ventricle
266
家族性地中海熱
Familial mediterranean fever
4
TUBB
💬
4. TUBB
×
Name
Full Name
TUBB
tubulin beta class I
10件:
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
10件:
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Colchicine
Colchicine
💬
4. TUBB
×
Name
Other Names
Colchicine
Colchicine (JP18/USP)
Colchicine (TN)
COLCRYS
GLOPERBA
MITIGARE
コルヒチン
Colchicine
7件:
2
2
,
42
,
46
,
56
,
93
,
210
,
266
💬
4. TUBB
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
42
結節性多発動脈炎
Polyarteritis nodosa
46
悪性関節リウマチ
Malignant rheumatoid arthritis
56
ベーチェット病
Behcet disease
93
原発性胆汁性胆管炎
Primary biliary cholangitis
210
単心室症
Single Ventricle
266
家族性地中海熱
Familial mediterranean fever
5
TUBB8
💬
5. TUBB8
×
Name
Full Name
TUBB8
tubulin beta 8 class VIII
10件:
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
10件:
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Colchicine
Colchicine
💬
5. TUBB8
×
Name
Other Names
Colchicine
Colchicine (JP18/USP)
Colchicine (TN)
COLCRYS
GLOPERBA
MITIGARE
コルヒチン
Colchicine
7件:
2
2
,
42
,
46
,
56
,
93
,
210
,
266
💬
5. TUBB8
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
42
結節性多発動脈炎
Polyarteritis nodosa
46
悪性関節リウマチ
Malignant rheumatoid arthritis
56
ベーチェット病
Behcet disease
93
原発性胆汁性胆管炎
Primary biliary cholangitis
210
単心室症
Single Ventricle
266
家族性地中海熱
Familial mediterranean fever
6
TUBB2B
💬
6. TUBB2B
×
Name
Full Name
TUBB2B
tubulin beta 2B class IIb
10件:
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
10件:
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Colchicine
Colchicine
💬
6. TUBB2B
×
Name
Other Names
Colchicine
Colchicine (JP18/USP)
Colchicine (TN)
COLCRYS
GLOPERBA
MITIGARE
コルヒチン
Colchicine
7件:
2
2
,
42
,
46
,
56
,
93
,
210
,
266
💬
6. TUBB2B
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
42
結節性多発動脈炎
Polyarteritis nodosa
46
悪性関節リウマチ
Malignant rheumatoid arthritis
56
ベーチェット病
Behcet disease
93
原発性胆汁性胆管炎
Primary biliary cholangitis
210
単心室症
Single Ventricle
266
家族性地中海熱
Familial mediterranean fever
7
IL1A
💬
7. IL1A
×
Name
Full Name
IL1A
interleukin 1 alpha
21件:
MAPK signaling pathway
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Necroptosis
,
Cellular senescence
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Leishmaniasis
,
Tuberculosis
,
Measles
,
Influenza A
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Fluid shear stress and atherosclerosis
21件:
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Necroptosis
,
Cellular senescenc
...
Rilonacept
Rilonacept
💬
7. IL1A
×
Name
Other Names
Rilonacept
Rilonacept (USAN/INN)
Arcalyst (TN)
リロナセプト
Rilonacept
4件:
51
51
,
106
,
107
,
266
💬
7. IL1A
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
106
クリオピリン関連周期熱症候群
Cryopyrin-associated periodic syndrome
107
若年性特発性関節炎
Juvenile idiopathic arthritis
266
家族性地中海熱
Familial mediterranean fever
8
IL1B
💬
8. IL1B
×
Name
Full Name
IL1B
interleukin 1 beta
44件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
44件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa
...
Rilonacept
Rilonacept
💬
8. IL1B
×
Name
Other Names
Rilonacept
Rilonacept (USAN/INN)
Arcalyst (TN)
リロナセプト
Rilonacept
4件:
51
51
,
106
,
107
,
266
💬
8. IL1B
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
106
クリオピリン関連周期熱症候群
Cryopyrin-associated periodic syndrome
107
若年性特発性関節炎
Juvenile idiopathic arthritis
266
家族性地中海熱
Familial mediterranean fever
9
IL1B
💬
9. IL1B
×
Name
Full Name
IL1B
interleukin 1 beta
44件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
44件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa
...
Canakinumab
Canakinumab
💬
9. IL1B
×
Name
Other Names
Canakinumab
Canakinumab (USAN/INN)
Canakinumab (genetical recombination) (JAN)
Ilaris (TN)
カナキヌマブ
イラリス
Canakinumab
10件:
46
46
,
56
,
84
,
106
,
107
,
108
,
113
,
266
,
267
,
269
💬
9. IL1B
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
56
ベーチェット病
Behcet disease
84
サルコイドーシス
Sarcoidosis
106
クリオピリン関連周期熱症候群
Cryopyrin-associated periodic syndrome
107
若年性特発性関節炎
Juvenile idiopathic arthritis
108
TNF受容体関連周期性症候群
TNF receptor-associated periodic syndrome
113
筋ジストロフィー
Muscular dystrophy
266
家族性地中海熱
Familial mediterranean fever
267
高ＩｇＤ症候群
Hyper-IgD syndrome
269
化膿性無菌性関節炎・壊疽性膿皮症・アクネ症候群;PAPA症候群
Pyogenic arthritis
10
IL1R1
💬
10. IL1R1
×
Name
Full Name
IL1R1
interleukin 1 receptor type 1
13件:
MAPK signaling pathway
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Th17 cell differentiation
,
Inflammatory mediator regulation of TRP channels
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Amoebiasis
,
Human cytomegalovirus infection
,
Human T-cell leukemia virus 1 infection
,
Fluid shear stress and atherosclerosis
13件:
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
O
...
Anakinra
Anakinra
💬
10. IL1R1
×
Name
Other Names
Anakinra
Anakinra (USAN/INN)
Kineret (TN)
アナキンラ
Anakinra
18件:
2
2
,
13
,
15
,
28
,
37
,
41
,
46
,
49
,
50
,
56
,
65
,
84
,
86
,
97
,
106
,
107
,
266
,
299
💬
10. IL1R1
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
15
封入体筋炎
Inclusion body myositis
28
全身性アミロイドーシス
Systemic amyloidosis
37
膿疱性乾癬（汎発型）
Generalised pustular psoriasis
41
巨細胞性動脈炎;側頭動脈炎
Giant cell arteritis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
50
皮膚筋炎／多発性筋炎
Dermatomyositis
56
ベーチェット病
Behcet disease
65
原発性免疫不全症候群
Primary immunodeficiency
84
サルコイドーシス
Sarcoidosis
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
97
潰瘍性大腸炎
Ulcerative colitis
106
クリオピリン関連周期熱症候群
Cryopyrin-associated periodic syndrome
107
若年性特発性関節炎
Juvenile idiopathic arthritis
266
家族性地中海熱
Familial mediterranean fever
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis