Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 IL17F 4件: Cytokine-cytokine receptor interaction 💬, IL-17 signaling pathway 💬, Th17 cell differentiation 💬, Inflammatory bowel disease 💬 D11550 Bimekizumab 3件: 46, 97, 271
2 CNR1 4件: Rap1 signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Retrograde endocannabinoid signaling 💬 D00306 Dronabinol 8件: 2, 8, 13, 36, 46, 96, 271, 298
3 CNR1 4件: Rap1 signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Retrograde endocannabinoid signaling 💬 D10915 Cannabidiol 19件: 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
4 CNR2 1件: Neuroactive ligand-receptor interaction 💬 D00306 Dronabinol 2件: 271, 298
5 CNR2 1件: Neuroactive ligand-receptor interaction 💬 D10915 Cannabidiol 1件: 271
6 ACE 6件: Renin-angiotensin system 💬, Renin secretion 💬, Chagas disease 💬, Coronavirus disease - COVID-19 💬, Hypertrophic cardiomyopathy 💬, Diabetic cardiomyopathy 💬 D00251 Captopril 8件: 6, 17, 46, 86, 96, 97, 107, 271
7 DHFR 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D00142 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
8 DHFR 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D02115 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
9 DHODH 3件: Pyrimidine metabolism 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬 D00749 Leflunomide 12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
10 DHFR2 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D00142 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
11 DHFR2 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D02115 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
12 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D00939 Alendronic acid 7件: 19, 41, 46, 50, 271, 274, 299
13 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D00941 Pamidronic acid 3件: 270, 271, 274
14 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D07119 Alendronic acid 7件: 19, 41, 46, 50, 271, 274, 299
15 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D07281 Pamidronic acid 3件: 270, 271, 274
16 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00407 Methylprednisolone 6件: 271, 283, 284, 285, 296, 300
17 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00472 Prednisolone 5件: 271, 296, 299, 300, 307
18 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00751 Methylprednisolone 6件: 271, 283, 284, 285, 296, 300
19 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00979 Methylprednisolone 6件: 271, 283, 284, 285, 296, 300
20 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00980 Prednisolone 5件: 271, 296, 299, 300, 307
21 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00981 Prednisolone 5件: 271, 296, 299, 300, 307
22 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00982 Prednisolone 5件: 271, 296, 299, 300, 307
23 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01239 Prednisolone 5件: 271, 296, 299, 300, 307
24 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01998 Prednisolone 5件: 271, 296, 299, 300, 307
25 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02156 Prednisolone 5件: 271, 296, 299, 300, 307
26 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D03301 Prednisolone 5件: 271, 296, 299, 300, 307
27 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D05000 Methylprednisolone 6件: 271, 283, 284, 285, 296, 300
28 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D05001 Methylprednisolone 6件: 271, 283, 284, 285, 296, 300
29 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D05002 Methylprednisolone 6件: 271, 283, 284, 285, 296, 300
30 SERPIND1 1件: Complement and coagulation cascades 💬 D08547 Sulodexide 2件: 271, 288
31 HMGCR 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, AMPK signaling pathway 💬, Bile secretion 💬 D00887 Atorvastatin 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
32 HMGCR 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, AMPK signaling pathway 💬, Bile secretion 💬 D01915 Rosuvastatin 11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
33 HMGCR 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, AMPK signaling pathway 💬, Bile secretion 💬 D07474 Atorvastatin 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
34 HMGCR 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, AMPK signaling pathway 💬, Bile secretion 💬 D08492 Rosuvastatin 11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
35 IL6R 12件: EGFR tyrosine kinase inhibitor resistance 💬, Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, HIF-1 signaling pathway 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Th17 cell differentiation 💬, Non-alcoholic fatty liver disease 💬, Human cytomegalovirus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬 D02596 Tocilizumab 21件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
36 IL6R 12件: EGFR tyrosine kinase inhibitor resistance 💬, Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, HIF-1 signaling pathway 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Th17 cell differentiation 💬, Non-alcoholic fatty liver disease 💬, Human cytomegalovirus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬 D10161 Sarilumab 5件: 41, 46, 84, 107, 271
37 IL12A 25件: Cytokine-cytokine receptor interaction 💬, Toll-like receptor signaling pathway 💬, RIG-I-like receptor signaling pathway 💬, C-type lectin receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Alcoholic liver disease 💬, Type I diabetes mellitus 💬, Pertussis 💬, Legionellosis 💬, Leishmaniasis 💬, Chagas disease 💬, African trypanosomiasis 💬, Malaria 💬, Toxoplasmosis 💬, Amoebiasis 💬, Tuberculosis 💬, Measles 💬, Influenza A 💬, Herpes simplex virus 1 infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Inflammatory bowel disease 💬, Allograft rejection 💬, Lipid and atherosclerosis 💬 D09214 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
38 IL12B 25件: Cytokine-cytokine receptor interaction 💬, Toll-like receptor signaling pathway 💬, RIG-I-like receptor signaling pathway 💬, C-type lectin receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Alcoholic liver disease 💬, Type I diabetes mellitus 💬, Pertussis 💬, Legionellosis 💬, Leishmaniasis 💬, Chagas disease 💬, African trypanosomiasis 💬, Toxoplasmosis 💬, Amoebiasis 💬, Tuberculosis 💬, Measles 💬, Influenza A 💬, Herpes simplex virus 1 infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Inflammatory bowel disease 💬, Allograft rejection 💬, Lipid and atherosclerosis 💬 D09214 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
39 IL17A 6件: Cytokine-cytokine receptor interaction 💬, IL-17 signaling pathway 💬, Th17 cell differentiation 💬, Alcoholic liver disease 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬 D09967 Secukinumab 8件: 13, 37, 41, 46, 107, 160, 269, 271
40 IL17A 6件: Cytokine-cytokine receptor interaction 💬, IL-17 signaling pathway 💬, Th17 cell differentiation 💬, Alcoholic liver disease 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬 D10071 Ixekizumab 6件: 36, 37, 107, 162, 269, 271
41 IL17A 6件: Cytokine-cytokine receptor interaction 💬, IL-17 signaling pathway 💬, Th17 cell differentiation 💬, Alcoholic liver disease 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬 D11550 Bimekizumab 3件: 46, 97, 271
42 JAK1 27件: EGFR tyrosine kinase inhibitor resistance 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, Signaling pathways regulating pluripotency of stem cells 💬, NOD-like receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Leishmaniasis 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis C 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human papillomavirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Viral carcinogenesis 💬, Pancreatic cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
43 JAK1 27件: EGFR tyrosine kinase inhibitor resistance 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, Signaling pathways regulating pluripotency of stem cells 💬, NOD-like receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Leishmaniasis 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis C 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human papillomavirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Viral carcinogenesis 💬, Pancreatic cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 D10871 Filgotinib 6件: 46, 53, 96, 97, 222, 271
44 JAK1 27件: EGFR tyrosine kinase inhibitor resistance 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, Signaling pathways regulating pluripotency of stem cells 💬, NOD-like receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Leishmaniasis 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis C 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human papillomavirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Viral carcinogenesis 💬, Pancreatic cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 D10994 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271
45 JAK2 24件: EGFR tyrosine kinase inhibitor resistance 💬, Chemokine signaling pathway 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Signaling pathways regulating pluripotency of stem cells 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Cholinergic synapse 💬, Prolactin signaling pathway 💬, Adipocytokine signaling pathway 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Growth hormone synthesis, secretion and action 💬, Leishmaniasis 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis B 💬, Influenza A 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
46 JAK3 15件: Chemokine signaling pathway 💬, PI3K-Akt signaling pathway 💬, Necroptosis 💬, Signaling pathways regulating pluripotency of stem cells 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Hepatitis B 💬, Measles 💬, Human T-cell leukemia virus 1 infection 💬, Epstein-Barr virus infection 💬, Pathways in cancer 💬, Viral carcinogenesis 💬, Non-small cell lung cancer 💬, Primary immunodeficiency 💬 D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
47 LTA 7件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, NF-kappa B signaling pathway 💬, TNF signaling pathway 💬, Type I diabetes mellitus 💬, Human T-cell leukemia virus 1 infection 💬, Herpes simplex virus 1 infection 💬 D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
48 ACHE 2件: Glycerophospholipid metabolism 💬, Cholinergic synapse 💬 D02068 Tacrine 3件: 46, 271, 299
49 ACHE 2件: Glycerophospholipid metabolism 💬, Cholinergic synapse 💬 D08555 Tacrine 3件: 46, 271, 299
50 SERPINC1 1件: Complement and coagulation cascades 💬 D08547 Sulodexide 2件: 271, 288
51 NFKB1 76件: Antifolate resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, cAMP signaling pathway 💬, Chemokine signaling pathway 💬, NF-kappa B signaling pathway 💬, HIF-1 signaling pathway 💬, Sphingolipid signaling pathway 💬, PI3K-Akt signaling pathway 💬, Apoptosis 💬, Longevity regulating pathway 💬, Cellular senescence 💬, Osteoclast differentiation 💬, Neutrophil extracellular trap formation 💬, Toll-like receptor signaling pathway 💬, NOD-like receptor signaling pathway 💬, RIG-I-like receptor signaling pathway 💬, Cytosolic DNA-sensing pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, TNF signaling pathway 💬, Neurotrophin signaling pathway 💬, Prolactin signaling pathway 💬, Adipocytokine signaling pathway 💬, Relaxin signaling pathway 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Alcoholic liver disease 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Epithelial cell signaling in Helicobacter pylori infection 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Salmonella infection 💬, Pertussis 💬, Legionellosis 💬, Yersinia infection 💬, Leishmaniasis 💬, Chagas disease 💬, Toxoplasmosis 💬, Amoebiasis 💬, Tuberculosis 💬, Hepatitis C 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human papillomavirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Human immunodeficiency virus 1 infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Viral carcinogenesis 💬, MicroRNAs in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Chemical carcinogenesis - reactive oxygen species 💬, Pancreatic cancer 💬, Prostate cancer 💬, Chronic myeloid leukemia 💬, Acute myeloid leukemia 💬, Small cell lung cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Inflammatory bowel disease 💬, Diabetic cardiomyopathy 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D01146 Iguratimod 4件: 46, 51, 53, 271
52 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D00455 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
53 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D01207 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
54 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D05259 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
55 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D05261 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
56 ATP4B 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D00455 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
57 ATP4B 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D01207 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
58 ATP4B 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D05259 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
59 ATP4B 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D05261 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
60 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D01355 Tramadol 5件: 46, 70, 78, 226, 271
61 OPRM1 3件: Neuroactive ligand-receptor interaction 💬, Estrogen signaling pathway 💬, Morphine addiction 💬 D08623 Tramadol 5件: 46, 70, 78, 226, 271
62 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271
63 PDE4B 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271
64 PDE4C 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271
65 PDE4D 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271
66 IL23A 9件: Cytokine-cytokine receptor interaction 💬, C-type lectin receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th17 cell differentiation 💬, Pertussis 💬, Tuberculosis 💬, Pathways in cancer 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬 D09214 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
67 IL23A 9件: Cytokine-cytokine receptor interaction 💬, C-type lectin receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th17 cell differentiation 💬, Pertussis 💬, Tuberculosis 💬, Pathways in cancer 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬 D10400 Tildrakizumab 2件: 162, 271
68 IL23A 9件: Cytokine-cytokine receptor interaction 💬, C-type lectin receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Th17 cell differentiation 💬, Pertussis 💬, Tuberculosis 💬, Pathways in cancer 💬, Inflammatory bowel disease 💬, Rheumatoid arthritis 💬 D11052 Risankizumab 4件: 37, 96, 97, 271
69 PTGER2 6件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Inflammatory mediator regulation of TRP channels 💬, Renin secretion 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬 D00419 Misoprostol 3件: 46, 70, 271
70 PTGER3 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Regulation of lipolysis in adipocytes 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬 D00419 Misoprostol 3件: 46, 70, 271
71 PTGER4 6件: Neuroactive ligand-receptor interaction 💬, Inflammatory mediator regulation of TRP channels 💬, Renin secretion 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Pathways in cancer 💬 D00419 Misoprostol 3件: 46, 70, 271
72 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D00118 Naproxen 4件: 13, 46, 107, 271
73 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D00126 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
74 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D00141 Indomethacin 3件: 225, 271, 298
75 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D00217 Acetaminophen 18件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
76 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D00903 Diclofenac 5件: 13, 34, 46, 78, 271
77 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D00904 Diclofenac 5件: 13, 34, 46, 78, 271
78 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D01122 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
79 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D01565 Indomethacin 3件: 225, 271, 298
80 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D02110 Indomethacin 3件: 225, 271, 298
81 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D04490 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
82 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D06606 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
83 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D07816 Diclofenac 5件: 13, 34, 46, 78, 271
84 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D08149 Loxoprofen 2件: 46, 271
85 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00118 Naproxen 4件: 13, 46, 107, 271
86 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00126 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
87 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00141 Indomethacin 3件: 225, 271, 298
88 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00217 Acetaminophen 18件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
89 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00567 Celecoxib 10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
90 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00903 Diclofenac 5件: 13, 34, 46, 78, 271
91 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00904 Diclofenac 5件: 13, 34, 46, 78, 271
92 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00969 Meloxicam 4件: 46, 49, 271, 296
93 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D01122 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
94 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D01565 Indomethacin 3件: 225, 271, 298
95 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D02110 Indomethacin 3件: 225, 271, 298
96 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D03710 Etoricoxib 2件: 46, 271
97 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection