Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 CSF3R 5件: Cytokine-cytokine receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬 D03235 Filgrastim 34件: 2, 6, 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
2 DHFR 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D00142 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
3 DHFR 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D02115 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
4 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D00799 Trifluoperazine 2件: 283, 284
5 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D01448 Trifluoperazine 2件: 283, 284
6 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D08636 Trifluoperazine 2件: 283, 284
7 DHFR2 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D00142 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
8 DHFR2 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D02115 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
9 EPOR 5件: Cytokine-cytokine receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬 D09946 Peginesatide 1件: 283
10 MTOR 51件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, ErbB signaling pathway 💬, HIF-1 signaling pathway 💬, Phospholipase D signaling pathway 💬, Autophagy - other 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Cellular senescence 💬, Apelin signaling pathway 💬, Neutrophil extracellular trap formation 💬, JAK-STAT signaling pathway 💬, Th17 cell differentiation 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Adipocytokine signaling pathway 💬, Type II diabetes mellitus 💬, Insulin resistance 💬, Growth hormone synthesis, secretion and action 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Shigellosis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Human immunodeficiency virus 1 infection 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, MicroRNAs in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Colorectal cancer 💬, Pancreatic cancer 💬, Glioma 💬, Prostate cancer 💬, Acute myeloid leukemia 💬, Breast cancer 💬, Hepatocellular carcinoma 💬, Gastric cancer 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Diabetic cardiomyopathy 💬 D00753 Sirolimus 41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
11 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00292 Dexamethasone 3件: 283, 296, 299
12 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00407 Methylprednisolone 5件: 283, 284, 285, 296, 300
13 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00473 Prednisone 7件: 283, 284, 285, 288, 299, 300, 331
14 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00751 Methylprednisolone 5件: 283, 284, 285, 296, 300
15 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00975 Dexamethasone 3件: 283, 296, 299
16 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00979 Methylprednisolone 5件: 283, 284, 285, 296, 300
17 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01510 Dexamethasone 3件: 283, 296, 299
18 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01615 Dexamethasone 3件: 283, 296, 299
19 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01632 Dexamethasone 3件: 283, 296, 299
20 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01948 Dexamethasone 3件: 283, 296, 299
21 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02174 Dexamethasone 3件: 283, 296, 299
22 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02591 Dexamethasone 3件: 283, 296, 299
23 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02592 Dexamethasone 3件: 283, 296, 299
24 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D05000 Methylprednisolone 5件: 283, 284, 285, 296, 300
25 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D05001 Methylprednisolone 5件: 283, 284, 285, 296, 300
26 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D05002 Methylprednisolone 5件: 283, 284, 285, 296, 300
27 IL2RA 11件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Measles 💬, Human T-cell leukemia virus 1 infection 💬, Pathways in cancer 💬 D03639 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284
28 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D00752 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
29 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05094 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
30 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05095 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
31 IMPDH1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05096 Mycophenolic acid 36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
32 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D00752 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
33 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05094 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
34 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05095 Mycophenolate mofetil 34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
35 IMPDH2 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D05096 Mycophenolic acid 36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
36 PPP3CA 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
37 PPP3CA 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
38 PPP3CA 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
39 PPP3CB 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
40 PPP3CB 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
41 PPP3CB 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
42 PPP3CC 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
43 PPP3CC 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
44 PPP3CC 33件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
45 PPP3R1 32件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
46 PPP3R1 32件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
47 PPP3R1 32件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
48 PPP3R2 32件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
49 PPP3R2 32件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
50 PPP3R2 32件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Wnt signaling pathway 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, C-type lectin receptor signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Renin secretion 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Tuberculosis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Human immunodeficiency virus 1 infection 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Lipid and atherosclerosis 💬 D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
51 PSMB5 8件: Proteasome 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D03150 Bortezomib 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331
52 RRM1 5件: Purine metabolism 💬, Pyrimidine metabolism 💬, Glutathione metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D01907 Fludarabine 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
53 RRM1 5件: Purine metabolism 💬, Pyrimidine metabolism 💬, Glutathione metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D07966 Fludarabine 19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
54 MS4A1 1件: Hematopoietic cell lineage 💬 D02994 Rituximab 7件: 283, 284, 285, 288, 296, 300, 331