Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 CTSC 2件: Lysosome 💬, Apoptosis 💬 D12120 Brensocatib 1件: 299
2 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D09916 Ivacaftor 1件: 299
3 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D10134 Lumacaftor 1件: 299
4 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D11041 Tezacaftor 1件: 299
5 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D11423 Deutivacaftor 1件: 299
6 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D11507 Elexacaftor 1件: 299
7 CFTR 8件: ABC transporters 💬, cAMP signaling pathway 💬, AMPK signaling pathway 💬, Tight junction 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Bile secretion 💬, Vibrio cholerae infection 💬 D11724 Galicaftor 1件: 299
8 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
9 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
10 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
11 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
12 PDE10A 4件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
13 CHRM1 8件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D00113 Atropine 2件: 2, 299
14 CHRM1 8件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D01077 Atropine 2件: 2, 299
15 CHRM1 8件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D02069 Atropine 2件: 2, 299
16 CHRM1 8件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D03011 Atropine 2件: 2, 299
17 CHRM1 8件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D03814 Atropine 2件: 2, 299
18 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D00113 Atropine 2件: 2, 299
19 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D00525 Pilocarpine 3件: 6, 53, 299
20 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D01077 Atropine 2件: 2, 299
21 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D02069 Atropine 2件: 2, 299
22 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D02200 Pilocarpine 3件: 6, 53, 299
23 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D03011 Atropine 2件: 2, 299
24 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D03814 Atropine 2件: 2, 299
25 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D05478 Pilocarpine 3件: 6, 53, 299
26 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D00113 Atropine 2件: 2, 299
27 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D00525 Pilocarpine 3件: 6, 53, 299
28 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D01077 Atropine 2件: 2, 299
29 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D02069 Atropine 2件: 2, 299
30 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D02200 Pilocarpine 3件: 6, 53, 299
31 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D03011 Atropine 2件: 2, 299
32 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D03814 Atropine 2件: 2, 299
33 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D05478 Pilocarpine 3件: 6, 53, 299
34 CHRM4 3件: Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D00113 Atropine 2件: 2, 299
35 CHRM4 3件: Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D01077 Atropine 2件: 2, 299
36 CHRM4 3件: Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D02069 Atropine 2件: 2, 299
37 CHRM4 3件: Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D03011 Atropine 2件: 2, 299
38 CHRM4 3件: Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D03814 Atropine 2件: 2, 299
39 CHRM5 6件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D00113 Atropine 2件: 2, 299
40 CHRM5 6件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D01077 Atropine 2件: 2, 299
41 CHRM5 6件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D02069 Atropine 2件: 2, 299
42 CHRM5 6件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D03011 Atropine 2件: 2, 299
43 CHRM5 6件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D03814 Atropine 2件: 2, 299
44 CLCN2 1件: Mineral absorption 💬 D04790 Lubiprostone 1件: 299
45 CNR2 1件: Neuroactive ligand-receptor interaction 💬 D11312 Ajulemic acid 1件: 299
46 ADORA1 7件: cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
47 ADORA1 7件: cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
48 ADORA1 7件: cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
49 ADORA1 7件: cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
50 ADORA1 7件: cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
51 ADORA2A 7件: Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Vascular smooth muscle contraction 💬, Parkinson disease 💬, Alcoholism 💬 D02017 Theophylline 2件: 236, 299
52 ADORA2B 5件: Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Vascular smooth muscle contraction 💬, Alcoholism 💬 D00371 Theophylline 2件: 236, 299
53 ADORA2B 5件: Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Vascular smooth muscle contraction 💬, Alcoholism 💬 D01712 Theophylline 2件: 236, 299
54 ADORA2B 5件: Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Vascular smooth muscle contraction 💬, Alcoholism 💬 D06103 Theophylline 2件: 236, 299
55 ADORA2B 5件: Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Vascular smooth muscle contraction 💬, Alcoholism 💬 D06104 Theophylline 2件: 236, 299
56 CSF2RA 4件: Cytokine-cytokine receptor interaction 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬 D05066 Molgramostim 3件: 97, 229, 299
57 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D00687 Salmeterol 1件: 299
58 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D01373 Formoterol 3件: 85, 228, 299
59 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D02147 Salbutamol 14件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299
60 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D05277 Formoterol 3件: 85, 228, 299
61 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D05792 Salmeterol 1件: 299
62 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D07990 Formoterol 3件: 85, 228, 299
63 DPP4 1件: Protein digestion and absorption 💬 D08516 Sitagliptin 1件: 299
64 DPP4 1件: Protein digestion and absorption 💬 D08996 Saxagliptin 1件: 299
65 DRD1 10件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Morphine addiction 💬, Alcoholism 💬 D00633 Dopamine 4件: 6, 7, 74, 299
66 DRD1 10件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Morphine addiction 💬, Alcoholism 💬 D07870 Dopamine 4件: 6, 7, 74, 299
67 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D00633 Dopamine 4件: 6, 7, 74, 299
68 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D07870 Dopamine 4件: 6, 7, 74, 299
69 DRD3 2件: Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D00633 Dopamine 4件: 6, 7, 74, 299
70 DRD3 2件: Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D07870 Dopamine 4件: 6, 7, 74, 299
71 DRD4 2件: Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D00633 Dopamine 4件: 6, 7, 74, 299
72 DRD4 2件: Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D07870 Dopamine 4件: 6, 7, 74, 299
73 DRD5 4件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D00633 Dopamine 4件: 6, 7, 74, 299
74 DRD5 4件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Dopaminergic synapse 💬 D07870 Dopamine 4件: 6, 7, 74, 299
75 AGTR1 16件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Phospholipase D signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Apelin signaling pathway 💬, Renin-angiotensin system 💬, Renin secretion 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Cushing syndrome 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Diabetic cardiomyopathy 💬 D00357 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
76 AGTR1 16件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Phospholipase D signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Apelin signaling pathway 💬, Renin-angiotensin system 💬, Renin secretion 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Cushing syndrome 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Diabetic cardiomyopathy 💬 D08146 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
77 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D00105 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
78 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D00554 Ethinylestradiol 4件: 13, 46, 49, 299
79 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01413 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
80 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01617 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
81 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01953 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
82 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04061 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
83 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04063 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
84 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04064 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
85 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04065 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
86 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D00105 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
87 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01413 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
88 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01617 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
89 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01953 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
90 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04061 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
91 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04063 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
92 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04064 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
93 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04065 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
94 FCER1A 4件: Sphingolipid signaling pathway 💬, Phospholipase D signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Asthma 💬 D05251 Omalizumab 7件: 46, 53, 65, 98, 162, 226, 299
95 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D00939 Alendronic acid 7件: 19, 41, 46, 50, 271, 274, 299
96 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D01968 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
97 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D06378 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
98 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D06379 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
99 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D07119 Alendronic acid 7件: 19, 41, 46, 50, 271, 274, 299
100 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D08689 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
101 GHR 5件: Cytokine-cytokine receptor interaction 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Growth hormone synthesis, secretion and action 💬 D02691 Somatotropin 23件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
102 GHR 5件: Cytokine-cytokine receptor interaction 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Growth hormone synthesis, secretion and action 💬 D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
103 GHR 5件: Cytokine-cytokine receptor interaction 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Growth hormone synthesis, secretion and action 💬 D04870 Mecasermin 6件: 65, 78, 96, 168, 265, 299
104 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
105 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
106 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
107 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
108 PDE7B 3件: Purine metabolism 💬, Metabolic pathways 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
109 GLP1R 3件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Insulin secretion 💬 D09889 Dulaglutide 2件: 13, 299
110 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00088 Hydrocortisone 1件: 299
111 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00246 Budesonide 1件: 299
112 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00292 Dexamethasone 1件: 299
113 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00472 Prednisolone 3件: 299, 300, 307
114 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00473 Prednisone 3件: 299, 300, 331
115 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00975 Dexamethasone 1件: 299
116 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00980 Prednisolone 3件: 299, 300, 307
117 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00981 Prednisolone 3件: 299, 300, 307
118 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00982 Prednisolone 3件: 299, 300, 307
119 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01239 Prednisolone 3件: 299, 300, 307
120 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01510 Dexamethasone 1件: 299
121 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01615 Dexamethasone 1件: 299
122 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01632 Dexamethasone 1件: 299
123 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01948 Dexamethasone 1件: 299
124 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01998 Prednisolone 3件: 299, 300, 307
125 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02156 Prednisolone 3件: 299, 300, 307
126 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02174 Dexamethasone 1件: 299
127 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02591 Dexamethasone 1件: 299
128 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02592 Dexamethasone 1件: 299
129 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D03301 Prednisolone 3件: 299, 300, 307
130 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D07981 Fluticasone 1件: 299
131 GUCY1A2 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Vascular smooth muscle contraction 💬, Gap junction 💬, Platelet activation 💬, Circadian entrainment 💬, Long-term depression 💬, Oxytocin signaling pathway 💬, Renin secretion 💬, Salivary secretion 💬 D09572 Riociguat 6件: 51, 84, 86, 88, 225, 299
132 GUCY1A1 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Vascular smooth muscle contraction 💬, Gap junction 💬, Platelet activation 💬, Circadian entrainment 💬, Long-term depression 💬, Oxytocin signaling pathway 💬, Renin secretion 💬, Salivary secretion 💬 D09572 Riociguat 6件: 51, 84, 86, 88, 225, 299
133 GUCY1B1 11件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬, Vascular smooth muscle contraction 💬, Gap junction 💬, Platelet activation 💬, Circadian entrainment 💬, Long-term depression 💬, Oxytocin signaling pathway 💬, Renin secretion 💬, Salivary secretion 💬 D09572 Riociguat 6件: 51, 84, 86, 88, 225, 299
134 HMGCR 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, AMPK signaling pathway 💬, Bile secretion 💬 D00434 Simvastatin 21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
135 HMGCR 4件: Terpenoid backbone biosynthesis 💬,