Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 CHRM1 8件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D00787 Trihexyphenidyl 2件: 5, 6
2 CHRM1 8件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D08638 Trihexyphenidyl 2件: 5, 6
3 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D00787 Trihexyphenidyl 2件: 5, 6
4 CHRM2 6件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D08638 Trihexyphenidyl 2件: 5, 6
5 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D00787 Trihexyphenidyl 2件: 5, 6
6 CHRM3 11件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Taste transduction 💬, Regulation of actin cytoskeleton 💬, Insulin secretion 💬, Salivary secretion 💬, Gastric acid secretion 💬, Pancreatic secretion 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D08638 Trihexyphenidyl 2件: 5, 6
7 CHRM4 3件: Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D00787 Trihexyphenidyl 2件: 5, 6
8 CHRM4 3件: Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬 D08638 Trihexyphenidyl 2件: 5, 6
9 CHRM5 6件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D00787 Trihexyphenidyl 2件: 5, 6
10 CHRM5 6件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Cholinergic synapse 💬, Regulation of actin cytoskeleton 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D08638 Trihexyphenidyl 2件: 5, 6
11 ADRA1D 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
12 ADRA1B 6件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
13 ADRA1A 7件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, AMPK signaling pathway 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Salivary secretion 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
14 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
15 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
16 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
17 ADRB1 11件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Gap junction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬, Dilated cardiomyopathy 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
18 ADRB2 9件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Adrenergic signaling in cardiomyocytes 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
19 ADRB3 8件: Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Thermogenesis 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Salivary secretion 💬, Chemical carcinogenesis - receptor activation 💬 D01277 Droxidopa 5件: 5, 6, 17, 169, 170
20 DRD1 10件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Morphine addiction 💬, Alcoholism 💬 D02004 Apomorphine 3件: 5, 6, 7
21 DRD1 10件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Morphine addiction 💬, Alcoholism 💬 D07460 Apomorphine 3件: 5, 6, 7
22 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D02004 Apomorphine 3件: 5, 6, 7
23 DRD2 8件: Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gap junction 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Alcoholism 💬 D07460 Apomorphine 3件: 5, 6, 7
24 ABAT 7件: Alanine, aspartate and glutamate metabolism 💬, Valine, leucine and isoleucine degradation 💬, beta-Alanine metabolism 💬, Propanoate metabolism 💬, Butanoate metabolism 💬, Metabolic pathways 💬, GABAergic synapse 💬 D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
25 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D01968 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
26 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D06378 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
27 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D06379 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
28 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D08689 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
29 GABRA1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
30 GABRA1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
31 GABRA2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
32 GABRA2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
33 GABRA3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
34 GABRA3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
35 GABRA4 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
36 GABRA4 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
37 GABRA5 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
38 GABRA5 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
39 GABRA6 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
40 GABRA6 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Taste transduction 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
41 GABRB1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
42 GABRB1 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
43 GABRB2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
44 GABRB2 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
45 GABRB3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
46 GABRB3 6件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
47 GABRD 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
48 GABRD 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
49 GABRE 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
50 GABRE 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
51 GABRG1 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
52 GABRG1 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
53 GABRG2 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
54 GABRG2 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
55 GABRG3 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
56 GABRG3 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
57 GABRP 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
58 GABRP 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
59 GAD1 7件: Alanine, aspartate and glutamate metabolism 💬, beta-Alanine metabolism 💬, Taurine and hypotaurine metabolism 💬, Butanoate metabolism 💬, Metabolic pathways 💬, GABAergic synapse 💬, Type I diabetes mellitus 💬 D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
60 GAD2 7件: Alanine, aspartate and glutamate metabolism 💬, beta-Alanine metabolism 💬, Taurine and hypotaurine metabolism 💬, Butanoate metabolism 💬, Metabolic pathways 💬, GABAergic synapse 💬, Type I diabetes mellitus 💬 D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
61 GRIA1 14件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Long-term depression 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Nicotine addiction 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
62 GRIA2 15件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Long-term depression 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
63 GRIA3 13件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Long-term depression 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Transcriptional misregulation in cancer 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
64 GRIA4 10件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Huntington disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Nicotine addiction 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
65 GRIK1 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
66 GRIK2 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
67 GRIK3 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
68 GRIK4 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
69 GRIK5 2件: Neuroactive ligand-receptor interaction 💬, Glutamatergic synapse 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
70 GRIN1 18件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
71 GRIN2A 19件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬, Systemic lupus erythematosus 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
72 GRIN2B 19件: Ras signaling pathway 💬, Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Dopaminergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬, Systemic lupus erythematosus 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
73 GRIN2C 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
74 GRIN2D 15件: Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Glutamatergic synapse 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Nicotine addiction 💬, Alcoholism 💬 D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
75 HCRTR1 1件: Neuroactive ligand-receptor interaction 💬 D10082 Suvorexant 3件: 5, 6, 13
76 HCRTR2 1件: Neuroactive ligand-receptor interaction 💬 D10082 Suvorexant 3件: 5, 6, 13
77 KIT 11件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Phospholipase D signaling pathway 💬, PI3K-Akt signaling pathway 💬, Hematopoietic cell lineage 💬, Melanogenesis 💬, Pathways in cancer 💬, Acute myeloid leukemia 💬, Breast cancer 💬, Central carbon metabolism in cancer 💬 D10229 Masitinib 6件: 2, 5, 6, 13, 46, 96
78 MAOB 14件: Glycine, serine and threonine metabolism 💬, Arginine and proline metabolism 💬, Histidine metabolism 💬, Tyrosine metabolism 💬, Phenylalanine metabolism 💬, Tryptophan metabolism 💬, Drug metabolism - cytochrome P450 💬, Metabolic pathways 💬, Serotonergic synapse 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Alcoholism 💬 D02562 Rasagiline 7件: 2, 5, 6, 13, 17, 58, 66
79 MAOB 14件: Glycine, serine and threonine metabolism 💬, Arginine and proline metabolism 💬, Histidine metabolism 💬, Tyrosine metabolism 💬, Phenylalanine metabolism 💬, Tryptophan metabolism 💬, Drug metabolism - cytochrome P450 💬, Metabolic pathways 💬, Serotonergic synapse 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Alcoholism 💬 D08469 Rasagiline 7件: 2, 5, 6, 13, 17, 58, 66
80 MAOB 14件: Glycine, serine and threonine metabolism 💬, Arginine and proline metabolism 💬, Histidine metabolism 💬, Tyrosine metabolism 💬, Phenylalanine metabolism 💬, Tryptophan metabolism 💬, Drug metabolism - cytochrome P450 💬, Metabolic pathways 💬, Serotonergic synapse 💬, Dopaminergic synapse 💬, Parkinson disease 💬, Cocaine addiction 💬, Amphetamine addiction 💬, Alcoholism 💬 D10829 Rasagiline 7件: 2, 5, 6, 13, 17, 58, 66
81 MAPT 4件: MAPK signaling pathway 💬, Alzheimer disease 💬, Parkinson disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D11210 Flortaucipir 3件: 5, 7, 127
82 MAPT 4件: MAPK signaling pathway 💬, Alzheimer disease 💬, Parkinson disease 💬, Pathways of neurodegeneration - multiple diseases 💬 D11293 Gosuranemab 1件: 5
83 ACHE 2件: Glycerophospholipid metabolism 💬, Cholinergic synapse 💬 D00670 Donepezil 9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
84 ACHE 2件: Glycerophospholipid metabolism 💬, Cholinergic synapse 💬 D02558 Rivastigmine 3件: 5, 6, 13
85 ACHE 2件: Glycerophospholipid metabolism 💬, Cholinergic synapse 💬 D03822 Rivastigmine 3件: 5, 6, 13
86 ACHE 2件: Glycerophospholipid metabolism 💬, Cholinergic synapse 💬 D07869 Donepezil 9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
87 GABRQ 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D00706 Zolpidem 3件: 5, 6, 46
88 GABRQ 5件: Neuroactive ligand-receptor interaction 💬, Retrograde endocannabinoid signaling 💬, GABAergic synapse 💬, Morphine addiction 💬, Nicotine addiction 💬 D08690 Zolpidem 3件: 5, 6, 46
89 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D00428 Salsalate 1件: 5
90 PTGS1 5件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, Platelet activation 💬, Serotonergic synapse 💬, Regulation of lipolysis in adipocytes 💬 D01183 Tolfenamic acid 1件: 5
91 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D00428 Salsalate 1件: 5
92 PTGS2 22件: Arachidonic acid metabolism 💬, Metabolic pathways 💬, NF-kappa B signaling pathway 💬, VEGF signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, TNF signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Serotonergic synapse 💬, Ovarian steroidogenesis 💬, Oxytocin signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Alzheimer disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Leishmaniasis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Pathways in cancer 💬, Chemical carcinogenesis - DNA adducts 💬, MicroRNAs in cancer 💬, Small cell lung cancer 💬 D01183 Tolfenamic acid 1件: 5
93 ROCK1 20件: cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Chemokine signaling pathway 💬, Sphingolipid signaling pathway 💬, Vascular smooth muscle contraction 💬, TGF-beta signaling pathway 💬, Axon guidance 💬, Focal adhesion 💬, Tight junction 💬, Platelet activation 💬, Leukocyte transendothelial migration 💬, Regulation of actin cytoskeleton 💬, Oxytocin signaling pathway 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Yersinia infection 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, MicroRNAs in cancer 💬 D07941 Fasudil 4件: 2, 5, 7, 51
94 SNAP25 2件: Synaptic vesicle cycle 💬, Insulin secretion 💬 D00783 Botulinum toxin type A 13件: 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226
95 ALDH5A1 3件: Alanine, aspartate and glutamate metabolism 💬, Butanoate metabolism 💬, Metabolic pathways 💬 D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
96 CACNA1I 7件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, Circadian entrainment 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, GnRH secretion 💬, Cushing syndrome 💬 D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
97 CACNA1H 7件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, Circadian entrainment 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, GnRH secretion 💬, Cushing syndrome 💬 D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
98 CACNA1G 8件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, Circadian entrainment 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, GnRH secretion 💬, Type II diabetes mellitus 💬, Cushing syndrome 💬 D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
99 ROCK2 21件: cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Chemokine signaling pathway 💬, Sphingolipid signaling pathway 💬, Vascular smooth muscle contraction 💬, Wnt signaling pathway 💬, Axon guidance 💬, Focal adhesion 💬, Tight junction 💬, Platelet activation 💬, Leukocyte transendothelial migration 💬, Regulation of actin cytoskeleton 💬, Oxytocin signaling pathway 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Salmonella infection 💬, Yersinia infection 💬, Human cytomegalovirus infection 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Lipid and atherosclerosis 💬 D07941 Fasudil 4件: 2, 5, 7, 51