Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 ADA 3件: Purine metabolism 💬, Metabolic pathways 💬, Primary immunodeficiency 💬 D11017 Elapegademase 1件: 65
2 TUBB3 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D01068 Vinblastine 2件: 34, 65
3 TUBB3 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D02197 Vincristine 4件: 26, 34, 65, 331
4 TUBB3 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08675 Vinblastine 2件: 34, 65
5 TUBB3 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08679 Vincristine 4件: 26, 34, 65, 331
6 TUBB4A 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D01068 Vinblastine 2件: 34, 65
7 TUBB4A 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D02197 Vincristine 4件: 26, 34, 65, 331
8 TUBB4A 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08675 Vinblastine 2件: 34, 65
9 TUBB4A 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08679 Vincristine 4件: 26, 34, 65, 331
10 TUBB4B 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D01068 Vinblastine 2件: 34, 65
11 TUBB4B 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D02197 Vincristine 4件: 26, 34, 65, 331
12 TUBB4B 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08675 Vinblastine 2件: 34, 65
13 TUBB4B 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08679 Vincristine 4件: 26, 34, 65, 331
14 ADORA1 7件: cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Regulation of lipolysis in adipocytes 💬, Renin secretion 💬, Morphine addiction 💬 D00045 Adenosine 3件: 13, 58, 65
15 ADORA2A 7件: Rap1 signaling pathway 💬, Calcium signaling pathway 💬, cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Vascular smooth muscle contraction 💬, Parkinson disease 💬, Alcoholism 💬 D00045 Adenosine 3件: 13, 58, 65
16 ADORA2B 5件: Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Vascular smooth muscle contraction 💬, Alcoholism 💬 D00045 Adenosine 3件: 13, 58, 65
17 ADORA3 3件: cGMP-PKG signaling pathway 💬, Sphingolipid signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00045 Adenosine 3件: 13, 58, 65
18 CSF3R 5件: Cytokine-cytokine receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬 D03235 Filgrastim 34件: 2, 6, 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
19 CSF3R 5件: Cytokine-cytokine receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Pathways in cancer 💬 D03247 Lenograstim 7件: 2, 13, 16, 18, 19, 57, 65
20 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00281 Clonidine 4件: 6, 65, 70, 78
21 ADRA2A 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00604 Clonidine 4件: 6, 65, 70, 78
22 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00281 Clonidine 4件: 6, 65, 70, 78
23 ADRA2B 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00604 Clonidine 4件: 6, 65, 70, 78
24 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00281 Clonidine 4件: 6, 65, 70, 78
25 ADRA2C 2件: cGMP-PKG signaling pathway 💬, Neuroactive ligand-receptor interaction 💬 D00604 Clonidine 4件: 6, 65, 70, 78
26 DHFR 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D00142 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
27 DHFR 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D02115 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
28 ABAT 7件: Alanine, aspartate and glutamate metabolism 💬, Valine, leucine and isoleucine degradation 💬, beta-Alanine metabolism 💬, Propanoate metabolism 💬, Butanoate metabolism 💬, Metabolic pathways 💬, GABAergic synapse 💬 D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
29 DHFR2 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D00142 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
30 DHFR2 5件: One carbon pool by folate 💬, Folate biosynthesis 💬, Metabolic pathways 💬, Biosynthesis of cofactors 💬, Antifolate resistance 💬 D02115 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
31 TUBB 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D01068 Vinblastine 2件: 34, 65
32 TUBB 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D02197 Vincristine 4件: 26, 34, 65, 331
33 TUBB 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08675 Vinblastine 2件: 34, 65
34 TUBB 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08679 Vincristine 4件: 26, 34, 65, 331
35 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D00105 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
36 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D00289 Danazol 5件: 60, 63, 64, 65, 285
37 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01413 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
38 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01413 Estradiol valerate 1件: 65
39 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01617 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
40 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01953 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
41 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04061 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
42 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04063 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
43 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04064 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
44 ESR1 9件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Endocrine and other factor-regulated calcium reabsorption 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04065 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
45 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D00105 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
46 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01413 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
47 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01413 Estradiol valerate 1件: 65
48 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01617 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
49 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D01953 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
50 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04061 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
51 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04063 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
52 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04064 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
53 ESR2 7件: Endocrine resistance 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, GnRH secretion 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Breast cancer 💬 D04065 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
54 FCER1A 4件: Sphingolipid signaling pathway 💬, Phospholipase D signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Asthma 💬 D05251 Omalizumab 7件: 46, 53, 65, 98, 162, 226, 299
55 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D01968 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
56 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D06378 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
57 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D06379 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
58 FDPS 4件: Terpenoid backbone biosynthesis 💬, Metabolic pathways 💬, Influenza A 💬, Human T-cell leukemia virus 1 infection 💬 D08689 Zoledronic acid 13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
59 FGFR2 13件: EGFR tyrosine kinase inhibitor resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, Calcium signaling pathway 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, Signaling pathways regulating pluripotency of stem cells 💬, Regulation of actin cytoskeleton 💬, Pathways in cancer 💬, Prostate cancer 💬, Gastric cancer 💬, Central carbon metabolism in cancer 💬 D05338 Palifermin 5件: 13, 36, 38, 39, 65
60 MTOR 51件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, ErbB signaling pathway 💬, HIF-1 signaling pathway 💬, Phospholipase D signaling pathway 💬, Autophagy - other 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Cellular senescence 💬, Apelin signaling pathway 💬, Neutrophil extracellular trap formation 💬, JAK-STAT signaling pathway 💬, Th17 cell differentiation 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Adipocytokine signaling pathway 💬, Type II diabetes mellitus 💬, Insulin resistance 💬, Growth hormone synthesis, secretion and action 💬, Alzheimer disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Spinocerebellar ataxia 💬, Pathways of neurodegeneration - multiple diseases 💬, Shigellosis 💬, Human cytomegalovirus infection 💬, Human papillomavirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Human immunodeficiency virus 1 infection 💬, Pathways in cancer 💬, Proteoglycans in cancer 💬, MicroRNAs in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Colorectal cancer 💬, Pancreatic cancer 💬, Glioma 💬, Prostate cancer 💬, Acute myeloid leukemia 💬, Breast cancer 💬, Hepatocellular carcinoma 💬, Gastric cancer 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Diabetic cardiomyopathy 💬 D00753 Sirolimus 41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
61 GABBR1 7件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, GABAergic synapse 💬, Taste transduction 💬, Estrogen signaling pathway 💬, GnRH secretion 💬, Morphine addiction 💬 D00241 Baclofen 7件: 2, 10, 13, 18, 65, 149, 206
62 GAD1 7件: Alanine, aspartate and glutamate metabolism 💬, beta-Alanine metabolism 💬, Taurine and hypotaurine metabolism 💬, Butanoate metabolism 💬, Metabolic pathways 💬, GABAergic synapse 💬, Type I diabetes mellitus 💬 D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
63 GAD2 7件: Alanine, aspartate and glutamate metabolism 💬, beta-Alanine metabolism 💬, Taurine and hypotaurine metabolism 💬, Butanoate metabolism 💬, Metabolic pathways 💬, GABAergic synapse 💬, Type I diabetes mellitus 💬 D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
64 GHR 5件: Cytokine-cytokine receptor interaction 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Growth hormone synthesis, secretion and action 💬 D02691 Somatotropin 23件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
65 GHR 5件: Cytokine-cytokine receptor interaction 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Growth hormone synthesis, secretion and action 💬 D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
66 GHR 5件: Cytokine-cytokine receptor interaction 💬, Neuroactive ligand-receptor interaction 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Growth hormone synthesis, secretion and action 💬 D04870 Mecasermin 6件: 65, 78, 96, 168, 265, 299
67 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00292 Dexamethasone 16件: 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
68 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00407 Methylprednisolone 23件: 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
69 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00472 Prednisolone 20件: 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
70 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00473 Prednisone 26件: 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
71 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00751 Methylprednisolone 23件: 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
72 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00975 Dexamethasone 16件: 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
73 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00979 Methylprednisolone 23件: 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
74 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00980 Prednisolone 20件: 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
75 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00981 Prednisolone 20件: 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
76 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00982 Prednisolone 20件: 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
77 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01239 Prednisolone 20件: 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
78 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01510 Dexamethasone 16件: 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
79 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01615 Dexamethasone 16件: 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
80 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01632 Dexamethasone 16件: 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
81 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01948 Dexamethasone 16件: 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
82 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01998 Prednisolone 20件: 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
83 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02156 Prednisolone 20件: 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
84 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02174 Dexamethasone 16件: 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
85 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02591 Dexamethasone 16件: 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
86 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02592 Dexamethasone 16件: 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
87 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D03301 Prednisolone 20件: 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
88 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D05000 Methylprednisolone 23件: 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
89 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D05001 Methylprednisolone 23件: 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
90 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D05002 Methylprednisolone 23件: 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
91 HPRT1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D00161 Mercaptopurine 4件: 65, 96, 97, 164
92 HPRT1 3件: Purine metabolism 💬, Drug metabolism - other enzymes 💬, Metabolic pathways 💬 D04931 Mercaptopurine 4件: 65, 96, 97, 164
93 HRH2 3件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gastric acid secretion 💬 D00422 Ranitidine 2件: 13, 65
94 HRH2 3件: Calcium signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Gastric acid secretion 💬 D00673 Ranitidine 2件: 13, 65
95 IFNGR1 18件: Cytokine-cytokine receptor interaction 💬, HIF-1 signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, JAK-STAT signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Leishmaniasis 💬, Chagas disease 💬, Toxoplasmosis 💬, Tuberculosis 💬, Influenza A 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Pathways in cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Inflammatory bowel disease 💬 D00747 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326
96 IFNGR2 17件: Cytokine-cytokine receptor interaction 💬, HIF-1 signaling pathway 💬, Necroptosis 💬, Osteoclast differentiation 💬, JAK-STAT signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Leishmaniasis 💬, Chagas disease 💬, Toxoplasmosis 💬, Tuberculosis 💬, Influenza A 💬, Herpes simplex virus 1 infection 💬, Pathways in cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Inflammatory bowel disease 💬 D00747 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326
97 TUBB8 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D01068 Vinblastine 2件: 34, 65
98 TUBB8 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D02197 Vincristine 4件: 26, 34, 65, 331
99 TUBB8 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08675 Vinblastine 2件: 34, 65
100 TUBB8 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08679 Vincristine 4件: 26, 34, 65, 331
101 TUBB2B 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D01068 Vinblastine 2件: 34, 65
102 TUBB2B 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D02197 Vincristine 4件: 26, 34, 65, 331
103 TUBB2B 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08675 Vinblastine 2件: 34, 65
104 TUBB2B 10件: Phagosome 💬, Gap junction 💬, Alzheimer disease 💬, Parkinson disease 💬, Amyotrophic lateral sclerosis 💬, Huntington disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Pathogenic Escherichia coli infection 💬, Salmonella infection 💬 D08679 Vincristine 4件: 26, 34, 65, 331
105 IGF1R 29件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Oocyte meiosis 💬, Autophagy - animal 💬, Endocytosis 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Focal adhesion 💬, Adherens junction 💬, Signaling pathways regulating pluripotency of stem cells 💬, Long-term depression 💬, Ovarian steroidogenesis 💬, Progesterone-mediated oocyte maturation 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Proteoglycans in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Breast cancer 💬, Hepatocellular carcinoma 💬 D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
106 IGF1R 29件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Oocyte meiosis 💬, Autophagy - animal 💬, Endocytosis 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Focal adhesion 💬, Adherens junction 💬, Signaling pathways regulating pluripotency of stem cells 💬, Long-term depression 💬, Ovarian steroidogenesis 💬, Progesterone-mediated oocyte maturation 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Proteoglycans in cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Breast cancer 💬, Hepatocellular carcinoma 💬 D04870 Mecasermin 6件: 65, 78, 96, 168, 265, 299
107 IL1R1 13件: MAPK signaling pathway 💬, Cytokine-cytokine receptor interaction 💬, NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Hematopoietic cell lineage 💬, Th17 cell differentiation 💬, Inflammatory mediator regulation of TRP channels 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Amoebiasis 💬, Human cytomegalovirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Fluid shear stress and atherosclerosis 💬 D02934 Anakinra 19件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
108 IL2RA 11件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Measles 💬, Human T-cell leukemia virus 1 infection 💬, Pathways in cancer 💬 D00748 Aldesleukin 6件: 2, 35, 49, 65, 96, 97
109 IL2RA 11件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Hematopoietic cell lineage 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Measles 💬, Human T-cell leukemia virus 1 infection 💬, Pathways in cancer 💬 D03639 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284
110 IL2RB 11件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, Endocytosis 💬, PI3K-Akt signaling pathway 💬, JAK-STAT signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, Measles 💬, Human T-cell leukemia virus 1 infection 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬 D00748 Aldesleukin 6件: 2, 35, 49, 65, 96, 97
111 IL2RG 12件: Cytokine-cytokine receptor interaction 💬, Viral protein interaction with cytokine and cytokine receptor 💬, Endocytosis 💬,