Target Gene/Pathway PATHWAY / GENE


Search results


No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 CYP19A1 3件: Steroid hormone biosynthesis 💬, Metabolic pathways 💬, Ovarian steroidogenesis 💬 D00964 Letrozole 2件: 81, 89
2 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00088 Hydrocortisone 5件: 81, 83, 97, 98, 299
3 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00292 Dexamethasone 12件: 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
4 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00472 Prednisolone 17件: 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
5 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00473 Prednisone 23件: 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
6 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00973 Cortisone acetate 1件: 81
7 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00975 Dexamethasone 12件: 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
8 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00976 Hydrocortisone cypionate 2件: 81, 83
9 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00980 Prednisolone 17件: 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
10 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00981 Prednisolone 17件: 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
11 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D00982 Prednisolone 17件: 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
12 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01239 Prednisolone 17件: 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
13 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01442 Hydrocortisone succinate 2件: 81, 83
14 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01510 Dexamethasone 12件: 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
15 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01615 Dexamethasone 12件: 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
16 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01632 Dexamethasone 12件: 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
17 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01948 Dexamethasone 12件: 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
18 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D01998 Prednisolone 17件: 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
19 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02156 Prednisolone 17件: 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
20 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02174 Dexamethasone 12件: 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
21 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02591 Dexamethasone 12件: 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
22 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D02592 Dexamethasone 12件: 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
23 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D03301 Prednisolone 17件: 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
24 NR3C1 1件: Neuroactive ligand-receptor interaction 💬 D07749 Cortisone 1件: 81
25 AR 4件: Oocyte meiosis 💬, Pathways in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Prostate cancer 💬 D00586 Flutamide 1件: 81
26 MC2R 5件: cAMP signaling pathway 💬, Neuroactive ligand-receptor interaction 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, Cushing syndrome 💬 D00146 Corticotropin 15件: 2, 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222
27 NR3C2 1件: Aldosterone-regulated sodium reabsorption 💬 D00986 Fludrocortisone 1件: 81
28 NR3C2 1件: Aldosterone-regulated sodium reabsorption 💬 D07967 Fludrocortisone 1件: 81
29 PPARG 11件: PPAR signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Osteoclast differentiation 💬, Thermogenesis 💬, Non-alcoholic fatty liver disease 💬, Huntington disease 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Thyroid cancer 💬, Lipid and atherosclerosis 💬 D00945 Pioglitazone 17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
30 PPARG 11件: PPAR signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Osteoclast differentiation 💬, Thermogenesis 💬, Non-alcoholic fatty liver disease 💬, Huntington disease 💬, Pathways in cancer 💬, Transcriptional misregulation in cancer 💬, Thyroid cancer 💬, Lipid and atherosclerosis 💬 D08378 Pioglitazone 17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
31 PRKAA1 20件: FoxO signaling pathway 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Apelin signaling pathway 💬, Tight junction 💬, Circadian rhythm 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Adipocytokine signaling pathway 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Alcoholic liver disease 💬, Hypertrophic cardiomyopathy 💬, Fluid shear stress and atherosclerosis 💬 D00944 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
32 PRKAA1 20件: FoxO signaling pathway 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Apelin signaling pathway 💬, Tight junction 💬, Circadian rhythm 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Adipocytokine signaling pathway 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Alcoholic liver disease 💬, Hypertrophic cardiomyopathy 💬, Fluid shear stress and atherosclerosis 💬 D04966 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
33 PRKAA2 20件: FoxO signaling pathway 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Apelin signaling pathway 💬, Tight junction 💬, Circadian rhythm 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Adipocytokine signaling pathway 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Alcoholic liver disease 💬, Hypertrophic cardiomyopathy 💬, Fluid shear stress and atherosclerosis 💬 D00944 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
34 PRKAA2 20件: FoxO signaling pathway 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Apelin signaling pathway 💬, Tight junction 💬, Circadian rhythm 💬, Thermogenesis 💬, Insulin signaling pathway 💬, Adipocytokine signaling pathway 💬, Oxytocin signaling pathway 💬, Glucagon signaling pathway 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Alcoholic liver disease 💬, Hypertrophic cardiomyopathy 💬, Fluid shear stress and atherosclerosis 💬 D04966 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
35 CACNA1C 34件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Cardiac muscle contraction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Circadian entrainment 💬, Long-term potentiation 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Cholinergic synapse 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Dopaminergic synapse 💬, Taste transduction 💬, Insulin secretion 💬, GnRH signaling pathway 💬, Oxytocin signaling pathway 💬, Renin secretion 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, GnRH secretion 💬, Type II diabetes mellitus 💬, Cushing syndrome 💬, Growth hormone synthesis, secretion and action 💬, Alzheimer disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Chemical carcinogenesis - receptor activation 💬, Hypertrophic cardiomyopathy 💬, Arrhythmogenic right ventricular cardiomyopathy 💬, Dilated cardiomyopathy 💬 D00437 Nifedipine 2件: 50, 81
36 CACNA1D 35件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Cellular senescence 💬, Cardiac muscle contraction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Tight junction 💬, Circadian entrainment 💬, Retrograde endocannabinoid signaling 💬, Glutamatergic synapse 💬, Cholinergic synapse 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Dopaminergic synapse 💬, Insulin secretion 💬, GnRH signaling pathway 💬, Oxytocin signaling pathway 💬, Renin secretion 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, GnRH secretion 💬, Type II diabetes mellitus 💬, Cushing syndrome 💬, Growth hormone synthesis, secretion and action 💬, Carbohydrate digestion and absorption 💬, Alzheimer disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Amphetamine addiction 💬, Chemical carcinogenesis - receptor activation 💬, Hypertrophic cardiomyopathy 💬, Arrhythmogenic right ventricular cardiomyopathy 💬, Dilated cardiomyopathy 💬 D00437 Nifedipine 2件: 50, 81
37 CACNA1F 27件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Cardiac muscle contraction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Retrograde endocannabinoid signaling 💬, Cholinergic synapse 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Insulin secretion 💬, GnRH signaling pathway 💬, Oxytocin signaling pathway 💬, Renin secretion 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, GnRH secretion 💬, Cushing syndrome 💬, Growth hormone synthesis, secretion and action 💬, Alzheimer disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Chemical carcinogenesis - receptor activation 💬, Hypertrophic cardiomyopathy 💬, Arrhythmogenic right ventricular cardiomyopathy 💬, Dilated cardiomyopathy 💬 D00437 Nifedipine 2件: 50, 81
38 CACNA1S 27件: MAPK signaling pathway 💬, Calcium signaling pathway 💬, cGMP-PKG signaling pathway 💬, cAMP signaling pathway 💬, Cardiac muscle contraction 💬, Adrenergic signaling in cardiomyocytes 💬, Vascular smooth muscle contraction 💬, Retrograde endocannabinoid signaling 💬, Cholinergic synapse 💬, Serotonergic synapse 💬, GABAergic synapse 💬, Insulin secretion 💬, GnRH signaling pathway 💬, Oxytocin signaling pathway 💬, Renin secretion 💬, Aldosterone synthesis and secretion 💬, Cortisol synthesis and secretion 💬, GnRH secretion 💬, Cushing syndrome 💬, Growth hormone synthesis, secretion and action 💬, Alzheimer disease 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Chemical carcinogenesis - receptor activation 💬, Hypertrophic cardiomyopathy 💬, Arrhythmogenic right ventricular cardiomyopathy 💬, Dilated cardiomyopathy 💬 D00437 Nifedipine 2件: 50, 81