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Showing 1 to 10 of 103 entries
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No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
EGFR
💬
1. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Gefitinib
Gefitinib
💬
1. EGFR
×
Name
Other Names
Gefitinib
Gefitinib (JP18/USAN/INN)
Iressa (TN)
ゲフィチニブ
イレッサ
Gefitinib
1件:
75
75
💬
1. EGFR
×
告示番号
日本語名
英語名
75
クッシング病
Cushing disease
2
EGFR
💬
2. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Cetuximab
Cetuximab
💬
2. EGFR
×
Name
Other Names
Cetuximab
Cetuximab (USAN/INN)
Cetuximab (genetical recombination) (JAN)
Erbitux (TN)
セツキシマブ
アービタックス
Cetuximab
2件:
51
51
,
86
💬
2. EGFR
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
3
EGFR
💬
3. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Erlotinib
Erlotinib
💬
3. EGFR
×
Name
Other Names
Erlotinib
Erlotinib (INN)
エルロチニブ
Erlotinib
1件:
94
94
💬
3. EGFR
×
告示番号
日本語名
英語名
94
原発性硬化性胆管炎
Primary sclerosing cholangitis
4
EGFR
💬
4. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Lapatinib
Lapatinib
💬
4. EGFR
×
Name
Other Names
Lapatinib
Lapatinib (INN)
ラパチニブ
Lapatinib
3件:
34
34
,
74
,
75
💬
4. EGFR
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
74
下垂体性PRL分泌亢進症
Prolactin secreting pituitary adenoma
75
クッシング病
Cushing disease
5
EGFR
💬
5. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Neratinib
Neratinib
💬
5. EGFR
×
Name
Other Names
Neratinib
Neratinib (USAN/INN)
ネラチニブ
Neratinib
1件:
34
34
💬
5. EGFR
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
6
EGFR
💬
6. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Icotinib
Icotinib
💬
6. EGFR
×
Name
Other Names
Icotinib
Icotinib
イコチニブ
Icotinib
1件:
34
34
💬
6. EGFR
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
7
EGFR
💬
7. EGFR
×
Name
Full Name
EGFR
epidermal growth factor receptor
48件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Phospholipase D signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Adherens junction
,
Gap junction
,
JAK-STAT signaling pathway
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Cushing syndrome
,
Epithelial cell signaling in Helicobacter pylori infection
,
Shigellosis
,
Hepatitis C
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Bladder cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
48件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
ErbB s
...
Tesevatinib
Tesevatinib
💬
7. EGFR
×
Name
Other Names
Tesevatinib
Tesevatinib (USAN/INN)
テセバチニブ
Tesevatinib
1件:
67
67
💬
7. EGFR
×
告示番号
日本語名
英語名
67
多発性嚢胞腎
Polycystic kidney disease
8
ESR1
💬
8. ESR1
×
Name
Full Name
ESR1
estrogen receptor 1
9件:
Endocrine resistance
Endocrine resistance
,
Estrogen signaling pathway
,
Prolactin signaling pathway
,
Thyroid hormone signaling pathway
,
Endocrine and other factor-regulated calcium reabsorption
,
Pathways in cancer
,
Proteoglycans in cancer
,
Chemical carcinogenesis - receptor activation
,
Breast cancer
9件:
Endocrine resistance
,
Estrogen signaling pathway
,
Prolactin signaling pathway
,
Thyroid hormone s
...
Estradiol
Estradiol
💬
8. ESR1
×
Name
Other Names
Estradiol
Estradiol (JAN/USP/INN)
Climara (TN)
Divigel (TN)
Estrace (TN)
Estraderm (TN)
Estrasorb (TN)
Estring (TN)
Estrogel (TN)
Innofem (TN)
Vagifem (TN)
Vivelle (TN)
IMVEXXY
MENOSTAR
MINIVELLE
VIVELLE-DOT
DOTTI
ESTRADIOL TRANSDERMAL SYSTEM
ESTRADIOL VAGINAL
ESTRADIOL VAGINAL CREAM
LYLLANA
YUVAFEM
エストラジオール
エストラーナ
ジュリナ
ディビゲル
ル・エストロジェル
Estradiol
7件:
13
13
,
46
,
49
,
65
,
76
,
226
,
299
💬
8. ESR1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
65
原発性免疫不全症候群
Primary immunodeficiency
76
下垂体性ゴナドトロピン分泌亢進症
Pituitary gonadotropin secretion hyperthyroidism
226
間質性膀胱炎（ハンナ型）
Interstitial cystitis with Hunners ulcer
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
9
ESR1
💬
9. ESR1
×
Name
Full Name
ESR1
estrogen receptor 1
9件:
Endocrine resistance
Endocrine resistance
,
Estrogen signaling pathway
,
Prolactin signaling pathway
,
Thyroid hormone signaling pathway
,
Endocrine and other factor-regulated calcium reabsorption
,
Pathways in cancer
,
Proteoglycans in cancer
,
Chemical carcinogenesis - receptor activation
,
Breast cancer
9件:
Endocrine resistance
,
Estrogen signaling pathway
,
Prolactin signaling pathway
,
Thyroid hormone s
...
Estriol
Estriol
💬
9. ESR1
×
Name
Other Names
Estriol
Estriol (JP18/USP)
Estriel (TN)
エストリオール
エストリール
ホーリン
Estriol
2件:
13
13
,
227
💬
9. ESR1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
227
オスラー病;遺伝性出血性末梢血管拡張症
Osler disease
10
ESR1
💬
10. ESR1
×
Name
Full Name
ESR1
estrogen receptor 1
9件:
Endocrine resistance
Endocrine resistance
,
Estrogen signaling pathway
,
Prolactin signaling pathway
,
Thyroid hormone signaling pathway
,
Endocrine and other factor-regulated calcium reabsorption
,
Pathways in cancer
,
Proteoglycans in cancer
,
Chemical carcinogenesis - receptor activation
,
Breast cancer
9件:
Endocrine resistance
,
Estrogen signaling pathway
,
Prolactin signaling pathway
,
Thyroid hormone s
...
Danazol
Danazol
💬
10. ESR1
×
Name
Other Names
Danazol
Danazol (JP18/USP/INN)
Danocrine (TN)
ダナゾール
ボンゾール
Danazol
5件:
60
60
,
63
,
64
,
65
,
285
💬
10. ESR1
×
告示番号
日本語名
英語名
60
再生不良性貧血
Aplastic anemia
63
特発性血小板減少性紫斑病;一次性免疫性血小板減少症
Idiopathic thrombocytopenic purpura
64
血栓性血小板減少性紫斑病
Thrombotic thrombocytopenic purpura
65
原発性免疫不全症候群
Primary immunodeficiency
285
ファンコニ貧血
Fanconi anemia