Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 TPH2 💬 4件: Tryptophan metabolism, Folate biosynthesis, Metabolic pathways, Serotonergic synapse Telotristat 💬 Telotristat 1件: 97 💬
2 DHFR 💬 5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance Methotrexate 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
3 DHFR2 💬 5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance Methotrexate 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
4 ALPL 💬 4件: Thiamine metabolism, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors Asfotase alfa 💬 Asfotase alfa 1件: 172 💬
5 PAH 💬 5件: Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Folate biosynthesis, Metabolic pathways, Biosynthesis of amino acids Pegvaliase 💬 Pegvaliase 1件: 240 💬
6 TPH1 💬 4件: Tryptophan metabolism, Folate biosynthesis, Metabolic pathways, Serotonergic synapse Telotristat 💬 Telotristat 1件: 97 💬