DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
Target Gene/Pathway
Pathway
/
Gene
Search
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Other
Search results
10
50
100
ALL
entries per page:
Showing 1 to 5 of 5 entries
Filter by
Reset
|
No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
RELA
💬
1. RELA
×
Name
Full Name
RELA
RELA proto-oncogene, NF-kB subunit
76件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Ras signaling pathway
,
cAMP signaling pathway
,
Chemokine signaling pathway
,
NF-kappa B signaling pathway
,
HIF-1 signaling pathway
,
Sphingolipid signaling pathway
,
Mitophagy - animal
,
PI3K-Akt signaling pathway
,
Apoptosis
,
Longevity regulating pathway
,
Cellular senescence
,
Osteoclast differentiation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
B cell receptor signaling pathway
,
TNF signaling pathway
,
Neurotrophin signaling pathway
,
Prolactin signaling pathway
,
Adipocytokine signaling pathway
,
Relaxin signaling pathway
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Cocaine addiction
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Viral carcinogenesis
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Pancreatic cancer
,
Prostate cancer
,
Chronic myeloid leukemia
,
Acute myeloid leukemia
,
Small cell lung cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Inflammatory bowel disease
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
76件:
Antifolate resistance
,
MAPK signaling pathway
,
Ras signaling pathway
,
cAMP signaling pathway
,
C
...
Edasalonexent
Edasalonexent
💬
1. RELA
×
Name
Other Names
Edasalonexent
Edasalonexent (USAN/INN)
エダサロネキセント
Edasalonexent
1件:
113
113
💬
1. RELA
×
告示番号
日本語名
英語名
113
筋ジストロフィー
Muscular dystrophy
2
SRC
💬
2. SRC
×
Name
Full Name
SRC
SRC proto-oncogene, non-receptor tyrosine kinase
42件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Rap1 signaling pathway
,
Chemokine signaling pathway
,
Mitophagy - animal
,
Endocytosis
,
Axon guidance
,
VEGF signaling pathway
,
Focal adhesion
,
Adherens junction
,
Tight junction
,
Gap junction
,
Platelet activation
,
Neutrophil extracellular trap formation
,
C-type lectin receptor signaling pathway
,
GABAergic synapse
,
Inflammatory mediator regulation of TRP channels
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Prolactin signaling pathway
,
Thyroid hormone signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Bacterial invasion of epithelial cells
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Yersinia infection
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Viral carcinogenesis
,
Proteoglycans in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Bladder cancer
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
42件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Rap1 s
...
Bosutinib
Bosutinib
💬
2. SRC
×
Name
Other Names
Bosutinib
Bosutinib (USAN)
ボスチニブ
Bosutinib
2件:
2
2
,
67
💬
2. SRC
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
67
多発性嚢胞腎
Polycystic kidney disease
3
SRC
💬
3. SRC
×
Name
Full Name
SRC
SRC proto-oncogene, non-receptor tyrosine kinase
42件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Rap1 signaling pathway
,
Chemokine signaling pathway
,
Mitophagy - animal
,
Endocytosis
,
Axon guidance
,
VEGF signaling pathway
,
Focal adhesion
,
Adherens junction
,
Tight junction
,
Gap junction
,
Platelet activation
,
Neutrophil extracellular trap formation
,
C-type lectin receptor signaling pathway
,
GABAergic synapse
,
Inflammatory mediator regulation of TRP channels
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Prolactin signaling pathway
,
Thyroid hormone signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Bacterial invasion of epithelial cells
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Yersinia infection
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Viral carcinogenesis
,
Proteoglycans in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Bladder cancer
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
42件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Rap1 s
...
Dasatinib
Dasatinib
💬
3. SRC
×
Name
Other Names
Dasatinib
Dasatinib (JAN/INN)
ダサチニブ
Dasatinib
2件:
51
51
,
85
💬
3. SRC
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
4
SRC
💬
4. SRC
×
Name
Full Name
SRC
SRC proto-oncogene, non-receptor tyrosine kinase
42件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Rap1 signaling pathway
,
Chemokine signaling pathway
,
Mitophagy - animal
,
Endocytosis
,
Axon guidance
,
VEGF signaling pathway
,
Focal adhesion
,
Adherens junction
,
Tight junction
,
Gap junction
,
Platelet activation
,
Neutrophil extracellular trap formation
,
C-type lectin receptor signaling pathway
,
GABAergic synapse
,
Inflammatory mediator regulation of TRP channels
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Prolactin signaling pathway
,
Thyroid hormone signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Bacterial invasion of epithelial cells
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Yersinia infection
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Viral carcinogenesis
,
Proteoglycans in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Bladder cancer
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
42件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Rap1 s
...
Dasatinib
Dasatinib
💬
4. SRC
×
Name
Other Names
Dasatinib
Dasatinib (USAN)
Dasatinib hydrate (JAN)
Sprycel (TN)
ダサチニブ水和物
スプリセル
Dasatinib
2件:
51
51
,
85
💬
4. SRC
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
5
SRC
💬
5. SRC
×
Name
Full Name
SRC
SRC proto-oncogene, non-receptor tyrosine kinase
42件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Rap1 signaling pathway
,
Chemokine signaling pathway
,
Mitophagy - animal
,
Endocytosis
,
Axon guidance
,
VEGF signaling pathway
,
Focal adhesion
,
Adherens junction
,
Tight junction
,
Gap junction
,
Platelet activation
,
Neutrophil extracellular trap formation
,
C-type lectin receptor signaling pathway
,
GABAergic synapse
,
Inflammatory mediator regulation of TRP channels
,
Regulation of actin cytoskeleton
,
GnRH signaling pathway
,
Estrogen signaling pathway
,
Prolactin signaling pathway
,
Thyroid hormone signaling pathway
,
Oxytocin signaling pathway
,
Relaxin signaling pathway
,
Bacterial invasion of epithelial cells
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Yersinia infection
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Viral carcinogenesis
,
Proteoglycans in cancer
,
Chemical carcinogenesis - receptor activation
,
Chemical carcinogenesis - reactive oxygen species
,
Bladder cancer
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
42件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Rap1 s
...
Saracatinib
Saracatinib
💬
5. SRC
×
Name
Other Names
Saracatinib
Saracatinib (USAN/INN)
サラカチニブ
Saracatinib
3件:
6
6
,
89
,
272
💬
5. SRC
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
89
リンパ脈管筋腫症
Lymphangioleiomyomatosis
272
進行性骨化性線維異形成症
Fibrodysplasia ossificans progressiva