Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

指定難病告示番号

1

7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...

3件: 28, 60, 61 💬

2

7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...

Acalabrutinib 💬

2件: 46, 61 💬

3

7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...

Zanubrutinib 💬

5件: 13, 63, 222, 300, 331 💬

告示番号	日本語名	英語名
13	多発性硬化症／視神経脊髄炎	Multiple sclerosis/Neuromyelitis optica
63	特発性血小板減少性紫斑病;一次性免疫性血小板減少症	Idiopathic thrombocytopenic purpura
222	一次性ネフローゼ症候群	Primary nephrotic syndrome
300	IgG4関連疾患	IgG4-related disease
331	特発性多中心性キャッスルマン病	Idiopathic multicentric castleman disease

4

7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...

Fenebrutinib 💬

1件: 13 💬

5

7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...

Branebrutinib 💬

3件: 46, 49, 53 💬

6

7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...

Orelabrutinib 💬

4件: 13, 49, 61, 63 💬

告示番号	日本語名	英語名
13	多発性硬化症／視神経脊髄炎	Multiple sclerosis/Neuromyelitis optica
49	全身性エリテマトーデス	Systemic lupus erythematosus
61	自己免疫性溶血性貧血	Autoimmune hemolytic anemia
63	特発性血小板減少性紫斑病;一次性免疫性血小板減少症	Idiopathic thrombocytopenic purpura

7

7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...

Remibrutinib 💬

2件: 13, 53 💬

8

7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor s ...

Evobrutinib 💬

3件: 13, 46, 49 💬

告示番号	日本語名	英語名
13	多発性硬化症／視神経脊髄炎	Multiple sclerosis/Neuromyelitis optica
46	悪性関節リウマチ	Malignant rheumatoid arthritis
49	全身性エリテマトーデス	Systemic lupus erythematosus

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