Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

指定難病告示番号

1

7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Name	Other Names
Estradiol	Estradiol (JAN/USP/INN) Climara (TN) Divigel (TN) Estrace (TN) Estraderm (TN) Estrasorb (TN) Estring (TN) Estrogel (TN) Innofem (TN) Vagifem (TN) Vivelle (TN) IMVEXXY MENOSTAR MINIVELLE VIVELLE-DOT DOTTI ESTRADIOL TRANSDERMAL SYSTEM ESTRADIOL VAGINAL ESTRADIOL VAGINAL CREAM LYLLANA YUVAFEM エストラジオールエストラーナジュリナディビゲルル・エストロジェル

7件: 13, 46, 49, 65, 76, 226, 299 💬

告示番号	日本語名	英語名
13	多発性硬化症／視神経脊髄炎	Multiple sclerosis/Neuromyelitis optica
46	悪性関節リウマチ	Malignant rheumatoid arthritis
49	全身性エリテマトーデス	Systemic lupus erythematosus
65	原発性免疫不全症候群	Primary immunodeficiency
76	下垂体性ゴナドトロピン分泌亢進症	Pituitary gonadotropin secretion hyperthyroidism
226	間質性膀胱炎（ハンナ型）	Interstitial cystitis with Hunners ulcer
299	嚢胞性線維症;膵囊胞線維症	Cystic fibrosis

2

7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

2件: 13, 227 💬

3

7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

2件: 46, 49 💬

4

7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Fulvestrant 💬

2件: 49, 86 💬

5

7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Estradiol valerate 💬

Estradiol valerate

1件: 65 💬

6

7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Estriol tripropionate 💬

2件: 13, 227 💬

7

7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

1件: 74 💬

8

7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Prasterone 💬

6件: 49, 53, 83, 86, 96, 113 💬

告示番号	日本語名	英語名
49	全身性エリテマトーデス	Systemic lupus erythematosus
53	シェーグレン症候群	Sjogren syndrome
83	アジソン病	Addison disease
86	肺動脈性肺高血圧症	Pulmonary arterial hypertension
96	クローン病;回腸末端炎	Crohn disease
113	筋ジストロフィー	Muscular dystrophy

9

7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Raloxifene 💬

1件: 46 💬

10

7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

3件: 2, 113, 227 💬

告示番号	日本語名	英語名
2	筋萎縮性側索硬化症	Amyotrophic lateral sclerosis
113	筋ジストロフィー	Muscular dystrophy
227	オスラー病;遺伝性出血性末梢血管拡張症	Osler disease

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