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No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
IL6
💬
1.
IL6
×
Name
Full Name
IL6
interleukin 6
51件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Intestinal immune network for IgA production
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Lipid and atherosclerosis
51件:
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor in
...
Pirfenidone
Pirfenidone
💬
1.
IL6
×
Name
Other Names
Pirfenidone
Pirfenidone (JAN/USAN/INN)
Esbriet (TN)
ピルフェニドン
ピレスパ
Pirfenidone
11件:
13
13
,
34
,
46
,
50
,
51
,
58
,
84
,
85
,
164
,
222
,
228
💬
1.
IL6
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
34
神経線維腫症
Neurofibromatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
50
皮膚筋炎／多発性筋炎
Dermatomyositis
51
全身性強皮症
Scleroderma
58
肥大型心筋症
Hypertrophic cardiomyopathy
84
サルコイドーシス
Sarcoidosis
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
164
眼皮膚白皮症
Oculocutaneous albinism
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
228
閉塞性細気管支炎
Bronchiolitis obliterans
2
IL6
💬
2.
IL6
×
Name
Full Name
IL6
interleukin 6
51件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Intestinal immune network for IgA production
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Lipid and atherosclerosis
51件:
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor in
...
Pomalidomide
Pomalidomide
💬
2.
IL6
×
Name
Other Names
Pomalidomide
Pomalidomide (JAN/USAN/INN)
Pomalyst (TN)
ポマリドミド
ポマリドマイド
ポマリスト
Pomalidomide
5件:
28
28
,
51
,
85
,
227
,
331
💬
2.
IL6
×
告示番号
日本語名
英語名
28
全身性アミロイドーシス
Systemic amyloidosis
51
全身性強皮症
Scleroderma
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
227
オスラー病;遺伝性出血性末梢血管拡張症
Osler disease
331
特発性多中心性キャッスルマン病
Idiopathic multicentric castleman disease
3
IL6
💬
3.
IL6
×
Name
Full Name
IL6
interleukin 6
51件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Intestinal immune network for IgA production
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Lipid and atherosclerosis
51件:
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor in
...
Siltuximab
Siltuximab
💬
3.
IL6
×
Name
Other Names
Siltuximab
Siltuximab (USAN/INN)
Sylvant (TN)
シルツキシマブ
Siltuximab
2件:
28
28
,
331
💬
3.
IL6
×
告示番号
日本語名
英語名
28
全身性アミロイドーシス
Systemic amyloidosis
331
特発性多中心性キャッスルマン病
Idiopathic multicentric castleman disease
4
IL6
💬
4.
IL6
×
Name
Full Name
IL6
interleukin 6
51件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Intestinal immune network for IgA production
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Lipid and atherosclerosis
51件:
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor in
...
Sirukumab
Sirukumab
💬
4.
IL6
×
Name
Other Names
Sirukumab
Sirukumab (USAN)
Sirukumab (genetical recombination) (JAN)
シルクマブ
Sirukumab
2件:
41
41
,
46
💬
4.
IL6
×
告示番号
日本語名
英語名
41
巨細胞性動脈炎;側頭動脈炎
Giant cell arteritis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
5
IL6
💬
5.
IL6
×
Name
Full Name
IL6
interleukin 6
51件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Intestinal immune network for IgA production
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Lipid and atherosclerosis
51件:
EGFR tyrosine kinase inhibitor resistance
,
Antifolate resistance
,
Cytokine-cytokine receptor in
...
Olokizumab
Olokizumab
💬
5.
IL6
×
Name
Other Names
Olokizumab
Olokizumab (INN)
オロキズマブ
Olokizumab
2件:
46
46
,
96
💬
5.
IL6
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
96
クローン病;回腸末端炎
Crohn disease
6
IL6
R
💬
6.
IL6
R
×
Name
Full Name
IL6
R
interleukin 6 receptor
12件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Th17 cell differentiation
,
Non-alcoholic fatty liver disease
,
Human cytomegalovirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
12件:
EGFR tyrosine kinase inhibitor resistance
,
Cytokine-cytokine receptor interaction
,
Viral protei
...
Tocilizumab
Tocilizumab
💬
6.
IL6
R
×
Name
Other Names
Tocilizumab
Tocilizumab (USAN/INN)
Tocilizumab (genetical recombination) (JAN)
Actemra (TN)
トシリズマブ
アクテムラ
Tocilizumab
21件:
2
2
,
11
,
13
,
40
,
41
,
42
,
43
,
44
,
46
,
49
,
50
,
51
,
53
,
54
,
55
,
56
,
86
,
107
,
266
,
271
,
331
💬
6.
IL6
R
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
11
重症筋無力症
Myasthenia gravis
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
40
高安動脈炎;大動脈炎症候群
Takayasu arteritis
41
巨細胞性動脈炎;側頭動脈炎
Giant cell arteritis
42
結節性多発動脈炎
Polyarteritis nodosa
43
顕微鏡的多発血管炎
Microscopic polyangiitis
44
多発血管炎性肉芽腫症;ウェゲナー肉芽腫症
Wegener granulomatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
50
皮膚筋炎／多発性筋炎
Dermatomyositis
51
全身性強皮症
Scleroderma
53
シェーグレン症候群
Sjogren syndrome
54
成人スチル病
Adult still disease
55
再発性多発軟骨炎
Relapsing polychondritis
56
ベーチェット病
Behcet disease
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
107
若年性特発性関節炎
Juvenile idiopathic arthritis
266
家族性地中海熱
Familial mediterranean fever
271
強直性脊椎炎
Ankylosing spondylitis
331
特発性多中心性キャッスルマン病
Idiopathic multicentric castleman disease
7
IL6
R
💬
7.
IL6
R
×
Name
Full Name
IL6
R
interleukin 6 receptor
12件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Th17 cell differentiation
,
Non-alcoholic fatty liver disease
,
Human cytomegalovirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
12件:
EGFR tyrosine kinase inhibitor resistance
,
Cytokine-cytokine receptor interaction
,
Viral protei
...
Sarilumab
Sarilumab
💬
7.
IL6
R
×
Name
Other Names
Sarilumab
Sarilumab (USAN)
Sarilumab (genetical receombination) (JAN)
Kevzara (TN)
サリルマブ
ケブザラ
Sarilumab
5件:
41
41
,
46
,
84
,
107
,
271
💬
7.
IL6
R
×
告示番号
日本語名
英語名
41
巨細胞性動脈炎;側頭動脈炎
Giant cell arteritis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
84
サルコイドーシス
Sarcoidosis
107
若年性特発性関節炎
Juvenile idiopathic arthritis
271
強直性脊椎炎
Ankylosing spondylitis
8
IL6
R
💬
8.
IL6
R
×
Name
Full Name
IL6
R
interleukin 6 receptor
12件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Th17 cell differentiation
,
Non-alcoholic fatty liver disease
,
Human cytomegalovirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
12件:
EGFR tyrosine kinase inhibitor resistance
,
Cytokine-cytokine receptor interaction
,
Viral protei
...
Satralizumab
Satralizumab
💬
8.
IL6
R
×
Name
Other Names
Satralizumab
Satralizumab (USAN/INN)
Satralizumab (genetical recombination) (JAN)
satralizumab-mwge
Enspryng (TN)
サトラリズマブ
エンスプリング
Satralizumab
3件:
11
11
,
13
,
86
💬
8.
IL6
R
×
告示番号
日本語名
英語名
11
重症筋無力症
Myasthenia gravis
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension