Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adrenergic signaling in cardiomyocytes 💬
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
2 AMPK signaling pathway 💬
1件: ADRA1A 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
3 Calcium signaling pathway 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
4 cAMP signaling pathway 💬
2件: ADRB1, ADRB2 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
5 cGMP-PKG signaling pathway 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
6 Chemical carcinogenesis - receptor activation 💬
3件: ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
7 Dilated cardiomyopathy 💬
1件: ADRB1 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
8 Gap junction 💬
1件: ADRB1 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
9 Neuroactive ligand-receptor interaction 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
10 Regulation of lipolysis in adipocytes 💬
3件: ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
11 Renin secretion 💬
3件: ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
12 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
13 Thermogenesis 💬
1件: ADRB3 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
14 Vascular smooth muscle contraction 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬