Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Acute myeloid leukemia 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
2 Adipocytokine signaling pathway 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
3 Adipocytokine signaling pathway 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
4 Adrenergic signaling in cardiomyocytes 💬
 1件: AGTR1 💬 D08146 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
5 Adrenergic signaling in cardiomyocytes 💬
 2件: AGTR1, AGTR2 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
6 Adrenergic signaling in cardiomyocytes 💬
 2件: AGTR1, AGTR2 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
7 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D00332 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬
8 African trypanosomiasis 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
9 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
10 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
11 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: AGTR1 💬 D08146 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
12 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
13 Alcoholic liver disease 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
14 Aldosterone synthesis and secretion 💬
 1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
15 Aldosterone synthesis and secretion 💬
 1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
16 Aldosterone synthesis and secretion 💬
 1件: AGTR1 💬 D08146 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
17 Allograft rejection 💬
 2件: CD80, CD86 💬 D03203 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
18 Allograft rejection 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
19 Alzheimer disease 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
20 Alzheimer disease 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
21 Alzheimer disease 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
22 Alzheimer disease 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
23 Amoebiasis 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
24 Amphetamine addiction 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
25 AMPK signaling pathway 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
26 Amyotrophic lateral sclerosis 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
27 Amyotrophic lateral sclerosis 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
28 Amyotrophic lateral sclerosis 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
29 Amyotrophic lateral sclerosis 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
30 Antifolate resistance 💬
 2件: DHFR, DHFR2 💬 D00142 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
31 Antifolate resistance 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
32 Antigen processing and presentation 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
33 Apelin signaling pathway 💬
 1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
34 Apelin signaling pathway 💬
 1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
35 Apelin signaling pathway 💬
 1件: AGTR1 💬 D08146 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
36 Apelin signaling pathway 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
37 Apoptosis 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
38 Apoptosis 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
39 Apoptosis - multiple species 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
40 Arrhythmogenic right ventricular cardiomyopathy 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D00332 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬
41 Ascorbate and aldarate metabolism 💬
 1件: GUSB 💬 D11004 💬 Vestronidase alfa 1件: 19 💬
42 Asthma 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
43 Autoimmune thyroid disease 💬
 2件: CD80, CD86 💬 D03203 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
44 Autophagy - animal 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
45 Autophagy - other 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
46 Axon guidance 💬
 1件: CXCR4 💬 D08971 💬 Plerixafor 5件: 19, 20, 65, 285, 299 💬
47 Axon guidance 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
48 B cell receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
49 Biosynthesis of cofactors 💬
 2件: DHFR, DHFR2 💬 D00142 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
50 Biosynthesis of cofactors 💬
 1件: GUSB 💬 D11004 💬 Vestronidase alfa 1件: 19 💬
51 Biosynthesis of cofactors 💬
 2件: NQO1, VKORC1 💬 D08682 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
52 Breast cancer 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
53 C-type lectin receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
54 C-type lectin receptor signaling pathway 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
55 Calcium signaling pathway 💬
 1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
56 Calcium signaling pathway 💬
 1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
57 Calcium signaling pathway 💬
 1件: AGTR1 💬 D08146 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
58 Calcium signaling pathway 💬
 1件: CXCR4 💬 D08971 💬 Plerixafor 5件: 19, 20, 65, 285, 299 💬
59 Calcium signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
60 Cardiac muscle contraction 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D00332 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬
61 Cell adhesion molecules 💬
 2件: CD80, CD86 💬 D03203 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
62 Cellular senescence 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
63 Cellular senescence 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
64 Central carbon metabolism in cancer 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
65 cGMP-PKG signaling pathway 💬
 1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
66 cGMP-PKG signaling pathway 💬
 1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
67 cGMP-PKG signaling pathway 💬
 1件: AGTR1 💬 D08146 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
68 cGMP-PKG signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
69 Chagas disease 💬
 1件: ACE 💬 D07892 💬 Enalapril 6件: 19, 46, 66, 113, 210, 222 💬
70 Chagas disease 💬
 1件: ACE 💬 D00362 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
71 Chagas disease 💬
 1件: ACE 💬 D08131 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
72 Chagas disease 💬
 1件: ACE 💬 D03752 💬 Quinapril 1件: 19 💬
73 Chagas disease 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
74 Chemical carcinogenesis - reactive oxygen species 💬
 1件: NQO1 💬 D08682 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
75 Chemical carcinogenesis - receptor activation 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
76 Chemical carcinogenesis - receptor activation 💬
 1件: VDR 💬 D00188 💬 Cholecalciferol 24件:  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
77 Chemical carcinogenesis - receptor activation 💬
 1件: VDR 💬 D00930 💬 Paricalcitol 5件: 19, 66, 218, 238, 298 💬
78 Chemokine signaling pathway 💬
 1件: CXCR4 💬 D08971 💬 Plerixafor 5件: 19, 20, 65, 285, 299 💬
79 Cholesterol metabolism 💬
 1件: LIPA 💬 D10377 💬 Sebelipase alfa 1件: 19 💬
80 Choline metabolism in cancer 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
81 Colorectal cancer 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
82 Colorectal cancer 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
83 Coronavirus disease - COVID-19 💬
 1件: ACE 💬 D07892 💬 Enalapril 6件: 19, 46, 66, 113, 210, 222 💬
84 Coronavirus disease - COVID-19 💬
 1件: ACE 💬 D00362 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
85 Coronavirus disease - COVID-19 💬
 1件: ACE 💬 D08131 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
86 Coronavirus disease - COVID-19 💬
 1件: ACE 💬 D03752 💬 Quinapril 1件: 19 💬
87 Coronavirus disease - COVID-19 💬
 1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
88 Coronavirus disease - COVID-19 💬
 1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
89 Coronavirus disease - COVID-19 💬
 1件: AGTR1 💬 D08146 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
90 Coronavirus disease - COVID-19 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
91 Cortisol synthesis and secretion 💬
 1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
92 Cortisol synthesis and secretion 💬
 1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
93 Cortisol synthesis and secretion 💬
 1件: AGTR1 💬 D08146 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
94 Cushing syndrome 💬
 1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
95 Cushing syndrome 💬
 1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
96 Cushing syndrome 💬
 1件: AGTR1 💬 D08146 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
97 Cytokine-cytokine receptor interaction 💬
 1件: CSF3R 💬 D03247 💬 Lenograstim 7件:  2 , 13, 16, 18, 19, 57, 65 💬
98 Cytokine-cytokine receptor interaction 💬
 1件: CXCR4 💬 D08971 💬 Plerixafor 5件: 19, 20, 65, 285, 299 💬
99 Cytokine-cytokine receptor interaction 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
100 Diabetic cardiomyopathy 💬
 1件: ACE 💬 D07892 💬 Enalapril 6件: 19, 46, 66, 113, 210, 222 💬
101 Diabetic cardiomyopathy 💬
 1件: ACE 💬 D00362 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
102 Diabetic cardiomyopathy 💬
 1件: ACE 💬 D08131 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
103 Diabetic cardiomyopathy 💬
 1件: ACE 💬 D03752 💬 Quinapril 1件: 19 💬
104 Diabetic cardiomyopathy 💬
 1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
105 Diabetic cardiomyopathy 💬
 1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
106 Diabetic cardiomyopathy 💬
 1件: AGTR1 💬 D08146 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
107 Diabetic cardiomyopathy 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
108 Dilated cardiomyopathy 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D00332 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬
109 Dilated cardiomyopathy 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
110 DNA replication 💬
 2件: POLA1, POLA2 💬 D03546 💬 Clofarabine 5件: 19, 20, 60, 234, 326 💬
111 Dopaminergic synapse 💬
 3件: PPP3CA, PPP3CB, PPP3CC 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
112 Drug metabolism - other enzymes 💬
 1件: GUSB 💬 D11004 💬 Vestronidase alfa 1件: 19 💬
113 Drug metabolism - other enzymes 💬
 2件: IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil 34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
114 Drug metabolism - other enzymes 💬
 2件: IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid 36件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
115 Drug metabolism - other enzymes 💬
 1件: RRM1 💬 D03546 💬 Clofarabine 5件: 19, 20, 60, 234, 326 💬
116 Drug metabolism - other enzymes 💬
 1件: RRM1 💬 D07966 💬 Fludarabine 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
117 Drug metabolism - other enzymes 💬
 1件: RRM2 💬 D00341 💬 Hydroxyurea 8件:  3 , 13, 19, 20, 65, 85, 86, 284 💬
118 EGFR tyrosine kinase inhibitor resistance 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
119 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: VDR 💬 D00188 💬 Cholecalciferol 24件:  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
120 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: VDR 💬 D00930 💬 Paricalcitol 5件: 19, 66, 218, 238, 298 💬
121 Endocrine resistance 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
122 Endocytosis 💬
 1件: CXCR4 💬 D08971 💬 Plerixafor 5件: 19, 20, 65, 285, 299 💬
123 Endocytosis 💬
 1件: TFRC 💬 D11812 💬 Pabinafusp alfa 1件: 19 💬
124 Endometrial cancer 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
125 Epstein-Barr virus infection 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
126 Epstein-Barr virus infection 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
127 ErbB signaling pathway 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
128 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
129 Ferroptosis 💬
 1件: TFRC 💬 D11812 💬 Pabinafusp alfa 1件: 19 💬
130 Fluid shear stress and atherosclerosis 💬
 1件: NQO1 💬 D08682 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
131 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
132 Folate biosynthesis 💬
 2件: DHFR, DHFR2 💬 D00142 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
133 GABAergic synapse 💬
 1件: SLC6A1 💬 D00332 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬
134 Galactose metabolism 💬
 1件: GLA 💬 D02784 💬 Agalsidase alfa 1件: 19 💬
135 Galactose metabolism 💬
 1件: GLA 💬 D03228 💬 Agalsidase beta 1件: 19 💬
136 Gastric cancer 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
137 Glioma 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
138 Glucagon signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
139 Glutamatergic synapse 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
140 Glutathione metabolism 💬
 1件: RRM1 💬 D03546 💬 Clofarabine 5件: 19, 20, 60, 234, 326 💬
141 Glutathione metabolism 💬
 1件: RRM1 💬 D07966 💬 Fludarabine 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
142 Glutathione metabolism 💬
 1件: RRM2 💬 D00341 💬 Hydroxyurea 8件:  3 , 13, 19, 20, 65, 85, 86, 284 💬
143 Glycerolipid metabolism 💬
 1件: GLA 💬 D02784 💬 Agalsidase alfa 1件: 19 💬
144 Glycerolipid metabolism 💬
 1件: GLA 💬 D03228 💬 Agalsidase beta 1件: 19 💬
145 Glycosaminoglycan degradation 💬
 1件: ARSB 💬 D06565 💬 Galsulfase 1件: 19 💬
146 Glycosaminoglycan degradation 💬
 1件: GALNS 💬 D10333 💬 Elosulfase alfa 1件: 19 💬
147 Glycosaminoglycan degradation 💬
 1件: GUSB 💬 D11004 💬 Vestronidase alfa 1件: 19 💬
148 Glycosaminoglycan degradation 💬
 1件: IDS 💬 D04499 💬 Idursulfase 1件: 19 💬
149 Glycosaminoglycan degradation 💬
 1件: IDS 💬 D11025 💬 Idursulfase beta 1件: 19 💬
150 Glycosaminoglycan degradation 💬
 1件: IDS 💬 D11812 💬 Pabinafusp alfa 1件: 19 💬
151 Glycosaminoglycan degradation 💬
 1件: IDUA 💬 D04670 💬 Laronidase 2件: 19, 256 💬
152 Glycosphingolipid biosynthesis - globo and isoglobo series 💬
 1件: GLA 💬 D02784 💬 Agalsidase alfa 1件: 19 💬
153 Glycosphingolipid biosynthesis - globo and isoglobo series 💬
 1件: GLA 💬 D03228 💬 Agalsidase beta 1件: 19 💬
154 Graft-versus-host disease 💬
 2件: CD80, CD86 💬 D03203 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
155 Graft-versus-host disease 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
156 Growth hormone synthesis, secretion and action 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
157 Hematopoietic cell lineage 💬
 1件: CSF3R 💬 D03247 💬 Lenograstim 7件:  2 , 13, 16, 18, 19, 57, 65 💬
158 Hematopoietic cell lineage 💬
 1件: MS4A1 💬 D02994 💬 Rituximab 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
159 Hematopoietic cell lineage 💬
 1件: TFRC 💬 D11812 💬 Pabinafusp alfa 1件: 19 💬
160 Hematopoietic cell lineage 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
161 Hepatitis B 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
162 Hepatitis B 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
163 Hepatitis C 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
164 Hepatitis C 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
165 Hepatocellular carcinoma 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
166 Hepatocellular carcinoma 💬
 1件: NQO1 💬 D08682 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
167 Herpes simplex virus 1 infection 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
168 Herpes simplex virus 1 infection 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
169 Herpes simplex virus 1 infection 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
170 HIF-1 signaling pathway 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
171 HIF-1 signaling pathway 💬
 1件: TFRC 💬 D11812 💬 Pabinafusp alfa 1件: 19 💬
172 Human cytomegalovirus infection 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
173 Human cytomegalovirus infection 💬
 1件: CXCR4 💬 D08971 💬 Plerixafor 5件: 19, 20, 65, 285, 299 💬
174 Human cytomegalovirus infection 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
175 Human cytomegalovirus infection 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
176 Human cytomegalovirus infection 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
177 Human immunodeficiency virus 1 infection 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
178 Human immunodeficiency virus 1 infection 💬
 1件: CXCR4 💬 D08971 💬 Plerixafor 5件: 19, 20, 65, 285, 299 💬
179 Human immunodeficiency virus 1 infection 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
180 Human immunodeficiency virus 1 infection 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
181 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
182 Human papillomavirus infection 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
183 Human papillomavirus infection 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
184 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 D07119 💬 Alendronic acid 7件: 19, 41, 46, 50, 271, 274, 299 💬
185 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
186 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬