Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 ABC transporters 💬
1件: ABCC8 💬 D00294 💬 Diazoxide 2件: 13, 193 💬
2 Acute myeloid leukemia 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
3 Adipocytokine signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
4 Adrenergic signaling in cardiomyocytes 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
5 Adrenergic signaling in cardiomyocytes 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
6 Adrenergic signaling in cardiomyocytes 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
7 Adrenergic signaling in cardiomyocytes 💬
5件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
8 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
9 Aldosterone synthesis and secretion 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
10 Alzheimer disease 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
11 Alzheimer disease 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
12 Amphetamine addiction 💬
6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
13 AMPK signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
14 Amyotrophic lateral sclerosis 💬
2件: GRIA1, GRIA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
15 Amyotrophic lateral sclerosis 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
16 Apelin signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
17 Arrhythmogenic right ventricular cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
18 Autophagy - animal 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
19 Autophagy - other 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
20 Bile secretion 💬
1件: CA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
21 Breast cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
22 Calcium signaling pathway 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
23 Calcium signaling pathway 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
24 Calcium signaling pathway 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
25 Calcium signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
26 Calcium signaling pathway 💬
1件: OXTR 💬 D07229 💬 Carbetocin 1件: 193 💬
27 Calcium signaling pathway 💬
1件: OXTR 💬 D00089 💬 Oxytocin 6件:  6 , 72, 127, 193, 206, 226 💬
28 cAMP signaling pathway 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
29 cAMP signaling pathway 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
30 cAMP signaling pathway 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
31 cAMP signaling pathway 💬
8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
32 cAMP signaling pathway 💬
1件: GLP1R 💬 D04121 💬 Exenatide 6件:  6 , 17, 72, 78, 193, 233 💬
33 cAMP signaling pathway 💬
1件: GLP1R 💬 D06404 💬 Liraglutide 3件:  6 , 75, 193 💬
34 cAMP signaling pathway 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
35 cAMP signaling pathway 💬
1件: OXTR 💬 D07229 💬 Carbetocin 1件: 193 💬
36 cAMP signaling pathway 💬
1件: OXTR 💬 D00089 💬 Oxytocin 6件:  6 , 72, 127, 193, 206, 226 💬
37 cAMP signaling pathway 💬
1件: SSTR2 💬 D00442 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
38 cAMP signaling pathway 💬
1件: SSTR2 💬 D06495 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
39 Carbohydrate digestion and absorption 💬
1件: CACNA1D 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
40 Cardiac muscle contraction 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
41 Cellular senescence 💬
1件: CACNA1D 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
42 Cellular senescence 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
43 Central carbon metabolism in cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
44 cGMP-PKG signaling pathway 💬
1件: ADRA2A 💬 D00606 💬 Guanfacine 1件: 193 💬
45 cGMP-PKG signaling pathway 💬
1件: ADRA2A 💬 D08031 💬 Guanfacine 1件: 193 💬
46 cGMP-PKG signaling pathway 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
47 cGMP-PKG signaling pathway 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
48 cGMP-PKG signaling pathway 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
49 cGMP-PKG signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
50 Chemical carcinogenesis - receptor activation 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
51 Chemical carcinogenesis - receptor activation 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
52 Chemical carcinogenesis - receptor activation 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
53 Chemical carcinogenesis - receptor activation 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
54 Chemical carcinogenesis - receptor activation 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
55 Choline metabolism in cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
56 Cholinergic synapse 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
57 Circadian entrainment 💬
6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
58 Cocaine addiction 💬
1件: GRIA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
59 Collecting duct acid secretion 💬
1件: CA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
60 Colorectal cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
61 Cortisol synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
62 Cortisol synthesis and secretion 💬
1件: CYP11B1 💬 D00410 💬 Metyrapone 2件: 75, 193 💬
63 Cortisol synthesis and secretion 💬
1件: CYP11B1 💬 D05019 💬 Metyrapone 2件: 75, 193 💬
64 Cortisol synthesis and secretion 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
65 Cushing syndrome 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
66 Cushing syndrome 💬
1件: CYP11B1 💬 D00410 💬 Metyrapone 2件: 75, 193 💬
67 Cushing syndrome 💬
1件: CYP11B1 💬 D05019 💬 Metyrapone 2件: 75, 193 💬
68 Cushing syndrome 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
69 Cytokine-cytokine receptor interaction 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
70 Diabetic cardiomyopathy 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
71 Dilated cardiomyopathy 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
72 Dilated cardiomyopathy 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
73 Dilated cardiomyopathy 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
74 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
75 Dopaminergic synapse 💬
7件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
76 EGFR tyrosine kinase inhibitor resistance 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
77 Endocrine resistance 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
78 ErbB signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
79 GABAergic synapse 💬
20件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
80 Gap junction 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
81 Gap junction 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
82 Gap junction 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
83 Gastric acid secretion 💬
1件: CA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
84 Gastric acid secretion 💬
1件: SSTR2 💬 D00442 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
85 Gastric acid secretion 💬
1件: SSTR2 💬 D06495 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
86 Gastric cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
87 Glioma 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
88 Glutamatergic synapse 💬
11件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
89 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
90 GnRH secretion 💬
1件: KCNJ11 💬 D00294 💬 Diazoxide 2件: 13, 193 💬
91 GnRH signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
92 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
93 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
94 Growth hormone synthesis, secretion and action 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
95 Growth hormone synthesis, secretion and action 💬
1件: SSTR2 💬 D00442 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
96 Growth hormone synthesis, secretion and action 💬
1件: SSTR2 💬 D06495 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
97 Hepatocellular carcinoma 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
98 Herpes simplex virus 1 infection 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
99 HIF-1 signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
100 Human cytomegalovirus infection 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
101 Human immunodeficiency virus 1 infection 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
102 Human papillomavirus infection 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
103 Huntington disease 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
104 Huntington disease 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
105 Hypertrophic cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
106 Insulin resistance 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
107 Insulin secretion 💬
2件: ABCC8, KCNJ11 💬 D00294 💬 Diazoxide 2件: 13, 193 💬
108 Insulin secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
109 Insulin secretion 💬
1件: GLP1R 💬 D04121 💬 Exenatide 6件:  6 , 17, 72, 78, 193, 233 💬
110 Insulin secretion 💬
1件: GLP1R 💬 D06404 💬 Liraglutide 3件:  6 , 75, 193 💬
111 Insulin signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
112 JAK-STAT signaling pathway 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
113 JAK-STAT signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
114 Kaposi sarcoma-associated herpesvirus infection 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
115 Long-term depression 💬
3件: GRIA1, GRIA2, GRIA3 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
116 Long-term potentiation 💬
3件: CACNA1C, GRIA1, GRIA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
117 Longevity regulating pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
118 Longevity regulating pathway - multiple species 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
119 MAPK signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
120 Metabolic pathways 💬
2件: CA2, CA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
121 Metabolic pathways 💬
1件: CYP11B1 💬 D00410 💬 Metyrapone 2件: 75, 193 💬
122 Metabolic pathways 💬
1件: CYP11B1 💬 D05019 💬 Metyrapone 2件: 75, 193 💬
123 Metabolic pathways 💬
1件: CYP19A1 💬 D00960 💬 Anastrozole 3件: 78, 86, 193 💬
124 MicroRNAs in cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
125 Morphine addiction 💬
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
126 mTOR signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
127 Neuroactive ligand-receptor interaction 💬
1件: ADRA2A 💬 D00606 💬 Guanfacine 1件: 193 💬
128 Neuroactive ligand-receptor interaction 💬
1件: ADRA2A 💬 D08031 💬 Guanfacine 1件: 193 💬
129 Neuroactive ligand-receptor interaction 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
130 Neuroactive ligand-receptor interaction 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
131 Neuroactive ligand-receptor interaction 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
132 Neuroactive ligand-receptor interaction 💬
1件: CNR1 💬 D05731 💬 Rimonabant 1件: 193 💬
133 Neuroactive ligand-receptor interaction 💬
2件: CNR1, CNR2 💬 D10915 💬 Cannabidiol 19件:  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
134 Neuroactive ligand-receptor interaction 💬
25件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
135 Neuroactive ligand-receptor interaction 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
136 Neuroactive ligand-receptor interaction 💬
1件: GLP1R 💬 D04121 💬 Exenatide 6件:  6 , 17, 72, 78, 193, 233 💬
137 Neuroactive ligand-receptor interaction 💬
1件: GLP1R 💬 D06404 💬 Liraglutide 3件:  6 , 75, 193 💬
138 Neuroactive ligand-receptor interaction 💬
1件: HRH3 💬 D10749 💬 Pitolisant 3件:  6 , 113, 193 💬
139 Neuroactive ligand-receptor interaction 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
140 Neuroactive ligand-receptor interaction 💬
1件: OXTR 💬 D07229 💬 Carbetocin 1件: 193 💬
141 Neuroactive ligand-receptor interaction 💬
1件: OXTR 💬 D00089 💬 Oxytocin 6件:  6 , 72, 127, 193, 206, 226 💬
142 Neuroactive ligand-receptor interaction 💬
1件: SSTR2 💬 D00442 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
143 Neuroactive ligand-receptor interaction 💬
1件: SSTR2 💬 D06495 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
144 Neutrophil extracellular trap formation 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
145 Nicotine addiction 💬
20件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
146 Nitrogen metabolism 💬
2件: CA2, CA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
147 Ovarian steroidogenesis 💬
1件: CYP19A1 💬 D00960 💬 Anastrozole 3件: 78, 86, 193 💬
148 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
149 Oxytocin signaling pathway 💬
1件: OXTR 💬 D07229 💬 Carbetocin 1件: 193 💬
150 Oxytocin signaling pathway 💬
1件: OXTR 💬 D00089 💬 Oxytocin 6件:  6 , 72, 127, 193, 206, 226 💬
151 Pancreatic cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
152 Pancreatic secretion 💬
1件: CA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
153 Pathways in cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
154 Pathways of neurodegeneration - multiple diseases 💬
8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
155 Pathways of neurodegeneration - multiple diseases 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
156 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
157 Phospholipase D signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
158 PI3K-Akt signaling pathway 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
159 PI3K-Akt signaling pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
160 Prion disease 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
161 Prostate cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
162 Proteoglycans in cancer 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
163 Proximal tubule bicarbonate reclamation 💬
2件: CA2, CA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
164 Rap1 signaling pathway 💬
1件: CNR1 💬 D10915 💬 Cannabidiol 19件:  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
165 Rap1 signaling pathway 💬
1件: CNR1 💬 D05731 💬 Rimonabant 1件: 193 💬
166 Regulation of lipolysis in adipocytes 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
167 Regulation of lipolysis in adipocytes 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
168 Regulation of lipolysis in adipocytes 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
169 Renin secretion 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
170 Renin secretion 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
171 Renin secretion 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
172 Renin secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
173 Retrograde endocannabinoid signaling 💬
24件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
174 Retrograde endocannabinoid signaling 💬
1件: CNR1 💬 D10915 💬 Cannabidiol 19件:  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
175 Retrograde endocannabinoid signaling 💬
1件: CNR1 💬 D05731 💬 Rimonabant 1件: 193 💬
176 Salivary secretion 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
177 Salivary secretion 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
178 Salivary secretion 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
179 Serotonergic synapse 💬
7件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
180 Shigellosis 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
181 Spinocerebellar ataxia 💬
3件: GRIA1, GRIA2, GRIA3 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
182 Spinocerebellar ataxia 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62,