Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 75 entries
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬Adipocytokine signaling pathway
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 1. Adipocytokine signaling pathway
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| 2 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
AGTR1 1件: AGTR1 💬Adrenergic signaling in cardiomyocytes
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Sparsentan Sparsentan 💬Adrenergic signaling in cardiomyocytes
| Sparsentan | 066 3件: 66, 218, 222 💬
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| 3 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
AGTR1 1件: AGTR1 💬Adrenergic signaling in cardiomyocytes
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Valsartan Valsartan 💬Adrenergic signaling in cardiomyocytes
| Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬
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| 4 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
AGTR1 1件: AGTR1 💬AGE-RAGE signaling pathway in diabetic complications
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Sparsentan Sparsentan 💬AGE-RAGE signaling pathway in diabetic complications
| Sparsentan | 066 3件: 66, 218, 222 💬
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| 5 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
AGTR1 1件: AGTR1 💬AGE-RAGE signaling pathway in diabetic complications
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Valsartan Valsartan 💬AGE-RAGE signaling pathway in diabetic complications
| Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬
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| 6 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬Alcoholic liver disease
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 6. Alcoholic liver disease
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| 7 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬Aldosterone synthesis and secretion
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Sparsentan Sparsentan 💬Aldosterone synthesis and secretion
| Sparsentan | 066 3件: 66, 218, 222 💬
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| 8 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬Aldosterone synthesis and secretion
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Valsartan Valsartan 💬Aldosterone synthesis and secretion
| Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬
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| 9 | Aldosterone-regulated sodium reabsorption 💬 13 genes, 14 drugs (DrugBank) and 25 diseases |
NR3C2 1件: NR3C2 💬Aldosterone-regulated sodium reabsorption
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Spironolactone Spironolactone 💬Aldosterone-regulated sodium reabsorption
| Spironolactone | 046 8件: 46, 58, 67, 86, 113, 210, 218, 225 💬9. Aldosterone-regulated sodium reabsorption
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| 10 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬AMPK signaling pathway
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Fluvastatin Fluvastatin 💬AMPK signaling pathway
| Fluvastatin | 079 3件: 79, 218, 222 💬
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