Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 82 entries
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬Adipocytokine signaling pathway
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 1. Adipocytokine signaling pathway
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| 2 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬Alcoholic liver disease
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 2. Alcoholic liver disease
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| 3 | Aldosterone-regulated sodium reabsorption 💬 13 genes, 14 drugs (DrugBank) and 25 diseases |
NR3C2 1件: NR3C2 💬Aldosterone-regulated sodium reabsorption
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Spironolactone Spironolactone 💬Aldosterone-regulated sodium reabsorption
| Spironolactone | 046 8件: 46, 58, 67, 86, 113, 210, 218, 225 💬3. Aldosterone-regulated sodium reabsorption
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| 4 | Aldosterone-regulated sodium reabsorption 💬 13 genes, 14 drugs (DrugBank) and 25 diseases |
SCNN1A 3件: SCNN1A, SCNN1B, SCNN1G 💬
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Amiloride Amiloride 💬Aldosterone-regulated sodium reabsorption
| Amiloride | 013 4件: 13, 67, 225, 299 💬
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| 5 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PTGS2 1件: PTGS2 💬Alzheimer disease
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Indomethacin Indomethacin 💬Alzheimer disease
| Indomethacin | 225 3件: 225, 271, 298 💬
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| 6 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬AMPK signaling pathway
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Atorvastatin Atorvastatin 💬AMPK signaling pathway
| Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬6. AMPK signaling pathway
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| 7 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬AMPK signaling pathway
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 7. AMPK signaling pathway
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| 8 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬Apelin signaling pathway
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 8. Apelin signaling pathway
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| 9 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases |
PTGS1 2件: PTGS1, PTGS2 💬
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Indomethacin Indomethacin 💬Arachidonic acid metabolism
| Indomethacin | 225 3件: 225, 271, 298 💬
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| 10 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬Autophagy - animal
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 10. Autophagy - animal
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