Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
3 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine maleate Trifluoperazine maleate 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
4 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine Trifluoperazine 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
5 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
6 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
7 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
8 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
9 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
10 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
11 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
12 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
13 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
14 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
15 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
16 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
17 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
18 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
19 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
20 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
21 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
22 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
23 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
24 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
25 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
26 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
27 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
28 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
29 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
30 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
31 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
32 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
33 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
34 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CD38 1件: CD38 💬 |
Isatuximab Isatuximab 💬 |
Isatuximab | 028 3件: 28, 61, 283 💬 💬 |
35 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
36 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
37 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
38 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine maleate Trifluoperazine maleate 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
39 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine Trifluoperazine 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
40 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
41 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
42 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
43 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
44 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
45 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
46 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
47 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
48 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
49 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
50 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine maleate Trifluoperazine maleate 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
51 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine Trifluoperazine 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
52 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
53 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R 1件: CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
54 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
EPOR 1件: EPOR 💬 |
Peginesatide Peginesatide 💬 |
Peginesatide | 283 1件: 283 💬 💬 |
55 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL2RA 1件: IL2RA 💬 |
Daclizumab Daclizumab 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 💬 |
56 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
57 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine maleate Trifluoperazine maleate 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
58 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine Trifluoperazine 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
59 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
60 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
61 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
62 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
Mycophenolate mofetil Mycophenolate mofetil 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 💬 |
63 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
Mycophenolic acid Mycophenolic acid 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬 |
64 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
RRM1 1件: RRM1 💬 |
Fludarabine Fludarabine 💬 |
Fludarabine | 011 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 💬 |
65 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
66 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
67 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
IL2RA 1件: IL2RA 💬 |
Daclizumab Daclizumab 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 💬 |
68 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
69 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 39 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
70 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine maleate Trifluoperazine maleate 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
71 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine Trifluoperazine 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
72 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
73 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
74 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
75 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
76 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
77 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
78 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
79 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
80 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 25 diseases |
RRM1 1件: RRM1 💬 |
Fludarabine Fludarabine 💬 |
Fludarabine | 011 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 💬 |
81 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
82 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CD38 1件: CD38 💬 |
Isatuximab Isatuximab 💬 |
Isatuximab | 028 3件: 28, 61, 283 💬 💬 |
83 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF3R 1件: CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
84 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
EPOR 1件: EPOR 💬 |
Peginesatide Peginesatide 💬 |
Peginesatide | 283 1件: 283 💬 💬 |
85 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL2RA 1件: IL2RA 💬 |
Daclizumab Daclizumab 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 💬 |
86 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
MS4A1 1件: MS4A1 💬 |
Rituximab Rituximab 💬 |
Rituximab | 011 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 💬 |
87 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
88 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
89 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
90 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
91 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
92 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
93 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
94 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
95 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
96 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
97 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
98 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
99 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL2RA 1件: IL2RA 💬 |
Daclizumab Daclizumab 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 💬 |
100 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
101 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
102 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
103 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
104 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
105 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
106 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
107 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
CSF3R 1件: CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
108 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
EPOR 1件: EPOR 💬 |
Peginesatide Peginesatide 💬 |
Peginesatide | 283 1件: 283 💬 💬 |
109 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL2RA 1件: IL2RA 💬 |
Daclizumab Daclizumab 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 💬 |
110 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
111 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
112 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
113 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
114 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
115 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
116 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
117 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
118 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
119 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
120 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
121 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
122 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
123 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
124 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
125 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
126 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL2RA 1件: IL2RA 💬 |
Daclizumab Daclizumab 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 💬 |
127 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CD38 1件: CD38 💬 |
Isatuximab Isatuximab 💬 |
Isatuximab | 028 3件: 28, 61, 283 💬 💬 |
128 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
129 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
Mycophenolate mofetil Mycophenolate mofetil 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 💬 |
130 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
Mycophenolic acid Mycophenolic acid 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬 |
131 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM1 1件: RRM1 💬 |
Fludarabine Fludarabine 💬 |
Fludarabine | 011 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 💬 |
132 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
133 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
134 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
135 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
136 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
137 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine maleate Trifluoperazine maleate 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
138 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 1件: DRD2 💬 |
Trifluoperazine Trifluoperazine 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 💬 |
139 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Dexamethasone Dexamethasone 💬 |
Dexamethasone | 013 22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 💬 |
140 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Methylprednisolone Methylprednisolone 💬 |
Methylprednisolone | 002 46件: 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 💬 |
141 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Prednisone Prednisone 💬 |
Prednisone | 002 45件: 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 💬 |
142 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
143 | Nicotinate and nicotinamide metabolism 💬 1 gene, 3 drugs (DrugBank) and 8 diseases |
CD38 1件: CD38 💬 |
Isatuximab Isatuximab 💬 |
Isatuximab | 028 3件: 28, 61, 283 💬 💬 |
144 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
Mycophenolate mofetil Mycophenolate mofetil 💬 |
Mycophenolate mofetil | < |