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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

A B C D E F G H  I  J K L M N O P Q R S T U V W X Y Z other

133 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  Acute myeloid leukemia 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2  Adipocytokine signaling pathway 
 4 genes, 3 drugs (DrugBank) and 55 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 3  African trypanosomiasis 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 4  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 5  Allograft rejection 
 3 genes, 2 drugs (DrugBank) and 33 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 6  Alzheimer disease 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 7  Amoebiasis 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 8  Amphetamine addiction 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 9  AMPK signaling pathway 
 3 genes, 2 drugs (DrugBank) and 46 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 10  Amyotrophic lateral sclerosis (ALS) 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 11  Antifolate resistance 
 3 genes, 2 drugs (DrugBank) and 40 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 12  Antigen processing and presentation 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 13  Apelin signaling pathway 
 3 genes, 2 drugs (DrugBank) and 46 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 14  Apoptosis 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 15  Asthma 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 16  Autoimmune thyroid disease 
 2 genes, 1 drug (DrugBank) and 24 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 17  Autophagy - animal 
 3 genes, 2 drugs (DrugBank) and 46 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 18  Autophagy - other 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 19  Axon guidance 
 6 genes, 2 drugs (DrugBank) and 46 diseases shown 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 20  B cell receptor signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 21  Breast cancer 
 3 genes, 2 drugs (DrugBank) and 37 diseases shown 
 2件: ESR1, PGR   D00289   Danazol   4件: 60, 64, 65, 285 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 22  C-type lectin receptor signaling pathway 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 23  Calcium signaling pathway 
 6 genes, 2 drugs (DrugBank) and 46 diseases shown 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 24  Cell adhesion molecules (CAMs) 
 3 genes, 2 drugs (DrugBank) and 25 diseases shown 
 1件: CD58   D02800   Alefacept   6件: 37, 60, 65, 164, 284, 285 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 25  Cellular senescence 
 6 genes, 2 drugs (DrugBank) and 69 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 26  Central carbon metabolism in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 27  cGMP-PKG signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 28  Chagas disease (American trypanosomiasis) 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 29  Chemokine signaling pathway 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 30  Choline metabolism in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 31  Circadian rhythm 
 2 genes, 1 drug (DrugBank) and 17 diseases shown 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 32  Colorectal cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 33  Cytokine-cytokine receptor interaction 
 4 genes, 3 drugs (DrugBank) and 38 diseases shown 
 1件: CSF3R   D03235   Filgrastim   28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 34  Dilated cardiomyopathy (DCM) 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 35  Dopaminergic synapse 
 3 genes, 1 drug (DrugBank) and 44 diseases shown 
 3件: PPP3CA, PPP3CB, PPP3CC   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 36  Drug metabolism - other enzymes 
 3 genes, 3 drugs (DrugBank) and 37 diseases shown 
 2件: IMPDH1, IMPDH2   D00752   Mycophenolate mofetil   32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 1件: RRM1   D01907   Fludarabine   17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 37  EGFR tyrosine kinase inhibitor resistance 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 38  Endocrine and other factor-regulated calcium reabsorption 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: ESR1   D00289   Danazol   4件: 60, 64, 65, 285 
 39  Endocrine resistance 
 2 genes, 2 drugs (DrugBank) and 37 diseases shown 
 1件: ESR1   D00289   Danazol   4件: 60, 64, 65, 285 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 40  Endocytosis 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 41  Epstein-Barr virus infection 
 2 genes, 2 drugs (DrugBank) and 19 diseases shown 
 1件: CD58   D02800   Alefacept   6件: 37, 60, 65, 164, 284, 285 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 42  ErbB signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 43  Estrogen signaling pathway 
 2 genes, 1 drug (DrugBank) and 4 diseases shown 
 2件: ESR1, PGR   D00289   Danazol   4件: 60, 64, 65, 285 
 44  Fc epsilon RI signaling pathway 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 45  Fluid shear stress and atherosclerosis 
 3 genes, 2 drugs (DrugBank) and 30 diseases shown 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 46  Folate biosynthesis 
 2 genes, 1 drug (DrugBank) and 33 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 47  FoxO signaling pathway 
 2 genes, 1 drug (DrugBank) and 17 diseases shown 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 48  Gastric cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 49  Glioma 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 50  Glucagon signaling pathway 
 7 genes, 2 drugs (DrugBank) and 57 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 51  Glutamatergic synapse 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 52  Glutathione metabolism 
 1 gene, 1 drug (DrugBank) and 17 diseases shown 
 1件: RRM1   D01907   Fludarabine   17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 53  Graft-versus-host disease 
 3 genes, 2 drugs (DrugBank) and 33 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 54  Growth hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 55  Hematopoietic cell lineage 
 3 genes, 3 drugs (DrugBank) and 60 diseases shown 
 1件: CSF3R   D03235   Filgrastim   28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 1件: MS4A1   D02994   Rituximab   42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 56  Hepatitis B 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 57  Hepatitis C 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 58  Hepatocellular carcinoma 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 59  Herpes simplex virus 1 infection 
 3 genes, 2 drugs (DrugBank) and 45 diseases shown 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 60  HIF-1 signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 61  Human cytomegalovirus infection 
 8 genes, 4 drugs (DrugBank) and 72 diseases shown 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 62  Human immunodeficiency virus 1 infection 
 8 genes, 4 drugs (DrugBank) and 72 diseases shown 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 63  Human papillomavirus infection 
 2 genes, 2 drugs (DrugBank) and 45 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 64  Human T-cell leukemia virus 1 infection 
 7 genes, 2 drugs (DrugBank) and 49 diseases shown 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 65  Hypertrophic cardiomyopathy (HCM) 
 3 genes, 2 drugs (DrugBank) and 30 diseases shown 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 66  IL-17 signaling pathway 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 67  Inflammatory bowel disease (IBD) 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 68  Influenza A 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 69  Insulin resistance 
 4 genes, 3 drugs (DrugBank) and 55 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 70  Insulin signaling pathway 
 3 genes, 2 drugs (DrugBank) and 46 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 71  Intestinal immune network for IgA production 
 3 genes, 2 drugs (DrugBank) and 25 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 72  JAK-STAT signaling pathway 
 2 genes, 2 drugs (DrugBank) and 48 diseases shown 
 1件: CSF3R   D03235   Filgrastim   28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 73  Kaposi sarcoma-associated herpesvirus infection 
 7 genes, 3 drugs (DrugBank) and 75 diseases shown 
 1件: CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 74  Legionellosis 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 75  Leishmaniasis 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 76  Leukocyte transendothelial migration 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 77  Long-term potentiation 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 78  Longevity regulating pathway 
 3 genes, 2 drugs (DrugBank) and 46 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 79  Longevity regulating pathway - multiple species 
 3 genes, 2 drugs (DrugBank) and 46 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 80  Malaria 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 81  MAPK signaling pathway 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 82  Metabolic pathways 
 5 genes, 4 drugs (DrugBank) and 49 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 2件: IMPDH1, IMPDH2   D00752   Mycophenolate mofetil   32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 1件: RRM1   D01907   Fludarabine   17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 83  MicroRNAs in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 84  mTOR signaling pathway 
 4 genes, 3 drugs (DrugBank) and 55 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 85  Natural killer cell mediated cytotoxicity 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 86  Necroptosis 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 87  Neuroactive ligand-receptor interaction 
 1 gene, 2 drugs (DrugBank) and 52 diseases shown 
 1件: NR3C1   D00407   Methylprednisolone   36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 
 D00751 
 D00979 
 D05000 
 D05001 
 D05002 
 D00473   Prednisone   44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 
 88  NF-kappa B signaling pathway 
 2 genes, 1 drug (DrugBank) and 15 diseases shown 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 89  NOD-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 90  Non-alcoholic fatty liver disease (NAFLD) 
 3 genes, 2 drugs (DrugBank) and 30 diseases shown 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 91  One carbon pool by folate 
 2 genes, 1 drug (DrugBank) and 33 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 92  Oocyte meiosis 
 7 genes, 3 drugs (DrugBank) and 45 diseases shown 
 1件: AR   D00462   Oxandrolone   2件: 211, 285 
 2件: AR, PGR   D00289   Danazol   4件: 60, 64, 65, 285 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 93  Osteoclast differentiation 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 94  Oxytocin signaling pathway 
 7 genes, 2 drugs (DrugBank) and 57 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 95  Pancreatic cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 96  Pathogenic Escherichia coli infection 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 97  Pathways in cancer 
 5 genes, 5 drugs (DrugBank) and 51 diseases shown 
 1件: AR   D00462   Oxandrolone   2件: 211, 285 
 2件: AR, ESR1   D00289   Danazol   4件: 60, 64, 65, 285 
 1件: CSF3R   D03235   Filgrastim   28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 98  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 6 genes, 2 drugs (DrugBank) and 69 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 99  Pertussis 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 100  Phospholipase D signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 101  PI3K-Akt signaling pathway 
 4 genes, 3 drugs (DrugBank) and 56 diseases shown 
 1件: CSF3R   D03235   Filgrastim   28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 102  Progesterone-mediated oocyte maturation 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: PGR   D00289   Danazol   4件: 60, 64, 65, 285 
 103  Prolactin signaling pathway 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: ESR1   D00289   Danazol   4件: 60, 64, 65, 285 
 104  Prostate cancer 
 2 genes, 3 drugs (DrugBank) and 38 diseases shown 
 1件: AR   D00289   Danazol   4件: 60, 64, 65, 285 
 D00462   Oxandrolone   2件: 211, 285 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 105  Proteoglycans in cancer 
 3 genes, 3 drugs (DrugBank) and 46 diseases shown 
 1件: ESR1   D00289   Danazol   4件: 60, 64, 65, 285 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 106  Purine metabolism 
 3 genes, 3 drugs (DrugBank) and 37 diseases shown 
 2件: IMPDH1, IMPDH2   D00752   Mycophenolate mofetil   32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 1件: RRM1   D01907   Fludarabine   17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 107  Pyrimidine metabolism 
 1 gene, 1 drug (DrugBank) and 17 diseases shown 
 1件: RRM1   D01907   Fludarabine   17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 108  Regulation of actin cytoskeleton 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 109  Renin secretion 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 110  Rheumatoid arthritis 
 3 genes, 2 drugs (DrugBank) and 33 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 111  RIG-I-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 112  Shigellosis 
 2 genes, 2 drugs (DrugBank) and 45 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 113  Sphingolipid signaling pathway 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 114  Systemic lupus erythematosus 
 3 genes, 2 drugs (DrugBank) and 33 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 115  T cell receptor signaling pathway 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 116  TGF-beta signaling pathway 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 117  Th1 and Th2 cell differentiation 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 118  Th17 cell differentiation 
 6 genes, 2 drugs (DrugBank) and 69 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 119  Thermogenesis 
 3 genes, 2 drugs (DrugBank) and 46 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 120  Thyroid hormone signaling pathway 
 2 genes, 2 drugs (DrugBank) and 37 diseases shown 
 1件: ESR1   D00289   Danazol   4件: 60, 64, 65, 285 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 121  Tight junction 
 2 genes, 1 drug (DrugBank) and 17 diseases shown 
 2件: PRKAA1, PRKAA2   D00944   Metformin   17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 122  TNF signaling pathway 
 2 genes, 1 drug (DrugBank) and 15 diseases shown 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 123  Toll-like receptor signaling pathway 
 3 genes, 2 drugs (DrugBank) and 33 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 124  Toxoplasmosis 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 125  Transcriptional misregulation in cancer 
 1 gene, 1 drug (DrugBank) and 24 diseases shown 
 1件: CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 126  Tuberculosis 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 127  Type I diabetes mellitus 
 4 genes, 2 drugs (DrugBank) and 33 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 128  Type II diabetes mellitus 
 2 genes, 2 drugs (DrugBank) and 45 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 129  VEGF signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 130  Viral myocarditis 
 2 genes, 1 drug (DrugBank) and 24 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 131  Viral protein interaction with cytokine and cytokine receptor 
 3 genes, 2 drugs (DrugBank) and 18 diseases shown 
 1件: CXCR4   D08971   Plerixafor   4件: 51, 65, 285, 299 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 132  Wnt signaling pathway 
 5 genes, 1 drug (DrugBank) and 44 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 133  Yersinia infection 
 1 gene, 1 drug (DrugBank) and 15 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 

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