Gene

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No.	KEGG PATHWAY	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Alcoholism 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
2	Alcoholism 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
3	Alzheimer disease 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
4	Alzheimer disease 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
5	Amphetamine addiction 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
6	Amphetamine addiction 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
7	Amyotrophic lateral sclerosis 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
8	Amyotrophic lateral sclerosis 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
9	Calcium signaling pathway 💬	4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
10	Calcium signaling pathway 💬	4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
11	cAMP signaling pathway 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
12	cAMP signaling pathway 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
13	cGMP-PKG signaling pathway 💬	3件: ADRA2A, ADRA2B, ADRA2C 💬	Dexmedetomidine 💬	Dexmedetomidine	14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 💬
14	Circadian entrainment 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
15	Circadian entrainment 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
16	Cocaine addiction 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
17	Cocaine addiction 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
18	Cortisol synthesis and secretion 💬	1件: KCNA4 💬	Dalfampridine 💬	Dalfampridine	5件: 3 , 4 , 6 , 13, 14 💬 💬
19	Cushing syndrome 💬	1件: KCNA4 💬	Dalfampridine 💬	Dalfampridine	5件: 3 , 4 , 6 , 13, 14 💬 💬
20	Dopaminergic synapse 💬	2件: GRIN2A, GRIN2B 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
21	Dopaminergic synapse 💬	2件: GRIN2A, GRIN2B 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
22	ECM-receptor interaction 💬	1件: SV2A 💬	Levetiracetam 💬	Levetiracetam	5件: 2 , 4 , 6 , 13, 307 💬 💬
23	Glutamatergic synapse 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
24	Glutamatergic synapse 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
25	Huntington disease 💬	2件: GRIN1, GRIN2B 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
26	Huntington disease 💬	2件: GRIN1, GRIN2B 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
27	Long-term potentiation 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
28	Long-term potentiation 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
29	Neuroactive ligand-receptor interaction 💬	3件: ADRA2A, ADRA2B, ADRA2C 💬	Dexmedetomidine 💬	Dexmedetomidine	14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 💬
30	Neuroactive ligand-receptor interaction 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
31	Neuroactive ligand-receptor interaction 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
32	Nicotine addiction 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
33	Nicotine addiction 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
34	Pathways of neurodegeneration - multiple diseases 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
35	Pathways of neurodegeneration - multiple diseases 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
36	Prion disease 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
37	Prion disease 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
38	Rap1 signaling pathway 💬	3件: GRIN1, GRIN2A, GRIN2B 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
39	Rap1 signaling pathway 💬	3件: GRIN1, GRIN2A, GRIN2B 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
40	Ras signaling pathway 💬	3件: GRIN1, GRIN2A, GRIN2B 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
41	Ras signaling pathway 💬	3件: GRIN1, GRIN2A, GRIN2B 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
42	Serotonergic synapse 💬	1件: KCND2 💬	Dalfampridine 💬	Dalfampridine	5件: 3 , 4 , 6 , 13, 14 💬 💬
43	Spinocerebellar ataxia 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
44	Spinocerebellar ataxia 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬
45	Spinocerebellar ataxia 💬	2件: KCNC3, KCND3 💬	Dalfampridine 💬	Dalfampridine	5件: 3 , 4 , 6 , 13, 14 💬 💬
46	Systemic lupus erythematosus 💬	2件: GRIN2A, GRIN2B 💬	Esketamine 💬	Esketamine	3件: 2 , 4 , 70 💬 💬
47	Systemic lupus erythematosus 💬	2件: GRIN2A, GRIN2B 💬	Ketamine 💬	Ketamine	8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬

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