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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

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139 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  Adipocytokine signaling pathway 
 2 genes, 5 drugs (DrugBank) and 38 diseases shown 
 1件: JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 2  Adrenergic signaling in cardiomyocytes 
 4 genes, 1 drug (DrugBank) and 2 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 3  African trypanosomiasis 
 6 genes, 5 drugs (DrugBank) and 36 diseases shown 
 4件: IL10, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 4  AGE-RAGE signaling pathway in diabetic complications 
 6 genes, 6 drugs (DrugBank) and 38 diseases shown 
 5件: CCL2, IL1A, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 5  Aldosterone synthesis and secretion 
 5 genes, 2 drugs (DrugBank) and 13 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 1件: MC2R   D00146   Corticotropin   12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 6  Allograft rejection 
 6 genes, 5 drugs (DrugBank) and 43 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 2件: IL10, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 7  Alzheimer disease 
 11 genes, 7 drugs (DrugBank) and 65 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1B, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 8  Amoebiasis 
 8 genes, 6 drugs (DrugBank) and 43 diseases shown 
 4件: IL10, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1R1, IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 9  Amphetamine addiction 
 7 genes, 3 drugs (DrugBank) and 56 diseases shown 
 2件: CACNA1C, CACNA1D   D00437   Nifedipine   2件: 50, 81 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 10  Amyotrophic lateral sclerosis (ALS) 
 6 genes, 5 drugs (DrugBank) and 64 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 11  Antifolate resistance 
 5 genes, 5 drugs (DrugBank) and 47 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 3件: IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 12  Antigen processing and presentation 
 1 gene, 3 drugs (DrugBank) and 34 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 13  Apoptosis 
 1 gene, 3 drugs (DrugBank) and 34 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 14  Arrhythmogenic right ventricular cardiomyopathy (ARVC) 
 4 genes, 1 drug (DrugBank) and 2 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 15  Asthma 
 2 genes, 3 drugs (DrugBank) and 34 diseases shown 
 2件: IL10, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 16  Autoimmune thyroid disease 
 4 genes, 3 drugs (DrugBank) and 28 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: IL10   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: TPO   D00401   Methimazole   1件: 50 
 17  Axon guidance 
 5 genes, 2 drugs (DrugBank) and 55 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 18  B cell receptor signaling pathway 
 5 genes, 2 drugs (DrugBank) and 55 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 19  Breast cancer 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: TNFSF11   D03684   Denosumab   7件: 46, 50, 93, 95, 96, 274, 299 
 20  C-type lectin receptor signaling pathway 
 12 genes, 7 drugs (DrugBank) and 65 diseases shown 
 4件: IL10, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 21  Calcium signaling pathway 
 9 genes, 3 drugs (DrugBank) and 56 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 22  cAMP signaling pathway 
 9 genes, 3 drugs (DrugBank) and 16 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 1件: MC2R   D00146   Corticotropin   12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 4件: PDE4A, PDE4B, PDE4C, PDE4D   D08860   Apremilast   5件: 46, 50, 56, 97, 271 
 23  Carbohydrate digestion and absorption 
 1 gene, 1 drug (DrugBank) and 2 diseases shown 
 1件: CACNA1D   D00437   Nifedipine   2件: 50, 81 
 24  Cardiac muscle contraction 
 4 genes, 1 drug (DrugBank) and 2 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 25  Cell adhesion molecules (CAMs) 
 3 genes, 2 drugs (DrugBank) and 25 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: PDCD1   D10316   Nivolumab   10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 
 26  Cellular senescence 
 8 genes, 4 drugs (DrugBank) and 58 diseases shown 
 1件: CACNA1D   D00437   Nifedipine   2件: 50, 81 
 2件: IL1A, IL6   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 27  cGMP-PKG signaling pathway 
 10 genes, 4 drugs (DrugBank) and 63 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 1件: PDE5A   D02229   Sildenafil   16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 
 D08514 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 28  Chagas disease (American trypanosomiasis) 
 7 genes, 5 drugs (DrugBank) and 36 diseases shown 
 5件: CCL2, IL10, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 29  Chemokine signaling pathway 
 3 genes, 3 drugs (DrugBank) and 19 diseases shown 
 1件: CCL2   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 2件: JAK2, JAK3   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 30  Cholinergic synapse 
 5 genes, 3 drugs (DrugBank) and 14 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 1件: JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 31  Circadian entrainment 
 2 genes, 1 drug (DrugBank) and 2 diseases shown 
 2件: CACNA1C, CACNA1D   D00437   Nifedipine   2件: 50, 81 
 32  Cortisol synthesis and secretion 
 5 genes, 2 drugs (DrugBank) and 13 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 1件: MC2R   D00146   Corticotropin   12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 33  Cushing syndrome 
 5 genes, 2 drugs (DrugBank) and 13 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 1件: MC2R   D00146   Corticotropin   12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 34  Cytokine-cytokine receptor interaction 
 15 genes, 9 drugs (DrugBank) and 48 diseases shown 
 6件: CCL2, IL10, IL1A, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1R1, IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 1件: IL6R   D02596   Tocilizumab   16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 1件: TNF   D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 1件: TNFSF11   D03684   Denosumab   7件: 46, 50, 93, 95, 96, 274, 299 
 35  Cytosolic DNA-sensing pathway 
 2 genes, 2 drugs (DrugBank) and 13 diseases shown 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1B, IL6   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 36  Dilated cardiomyopathy (DCM) 
 5 genes, 4 drugs (DrugBank) and 35 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 37  Dopaminergic synapse 
 5 genes, 3 drugs (DrugBank) and 56 diseases shown 
 2件: CACNA1C, CACNA1D   D00437   Nifedipine   2件: 50, 81 
 3件: PPP3CA, PPP3CB, PPP3CC   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 38  EGFR tyrosine kinase inhibitor resistance 
 4 genes, 4 drugs (DrugBank) and 29 diseases shown 
 1件: IL6   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL6R   D02596   Tocilizumab   16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 2件: JAK1, JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 39  Endocrine and other factor-regulated calcium reabsorption 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: VDR   D01518   Alfacalcidol   6件: 41, 46, 49, 50, 96, 235 
 40  Endocytosis 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 41  Epstein-Barr virus infection 
 5 genes, 5 drugs (DrugBank) and 38 diseases shown 
 2件: IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: JAK1   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 3件: JAK1, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 42  Fc epsilon RI signaling pathway 
 1 gene, 3 drugs (DrugBank) and 34 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 43  Fluid shear stress and atherosclerosis 
 6 genes, 5 drugs (DrugBank) and 42 diseases shown 
 4件: CCL2, IL1A, IL1B, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1R1, IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 44  Folate biosynthesis 
 2 genes, 1 drug (DrugBank) and 33 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 45  FoxO signaling pathway 
 3 genes, 2 drugs (DrugBank) and 11 diseases shown 
 2件: IL10, IL6   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: S1PR1   D11460   Siponimod   2件: 13, 50 
 46  GABAergic synapse 
 4 genes, 1 drug (DrugBank) and 2 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 47  Glucagon signaling pathway 
 5 genes, 2 drugs (DrugBank) and 55 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 48  Glutamatergic synapse 
 7 genes, 3 drugs (DrugBank) and 56 diseases shown 
 2件: CACNA1C, CACNA1D   D00437   Nifedipine   2件: 50, 81 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 49  GnRH secretion 
 4 genes, 1 drug (DrugBank) and 2 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 50  GnRH signaling pathway 
 4 genes, 1 drug (DrugBank) and 2 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 51  Graft-versus-host disease 
 6 genes, 5 drugs (DrugBank) and 43 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 4件: IL1A, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 52  Growth hormone synthesis, secretion and action 
 5 genes, 3 drugs (DrugBank) and 14 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 1件: JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 53  Hematopoietic cell lineage 
 9 genes, 8 drugs (DrugBank) and 65 diseases shown 
 4件: IL1A, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1R1, IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 1件: IL6R   D02596   Tocilizumab   16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 1件: MS4A1   D02994   Rituximab   42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 54  Hepatitis B 
 6 genes, 5 drugs (DrugBank) and 38 diseases shown 
 2件: IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 2件: JAK1, JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 4件: JAK1, JAK2, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 55  Hepatitis C 
 3 genes, 5 drugs (DrugBank) and 38 diseases shown 
 1件: JAK1   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 2件: JAK1, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 56  Herpes simplex virus 1 infection 
 10 genes, 7 drugs (DrugBank) and 39 diseases shown 
 4件: CCL2, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: JAK1, JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 3件: JAK1, JAK2, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 1件: TNF   D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 57  HIF-1 signaling pathway 
 2 genes, 2 drugs (DrugBank) and 23 diseases shown 
 1件: IL6   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL6R   D02596   Tocilizumab   16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 58  Human cytomegalovirus infection 
 12 genes, 10 drugs (DrugBank) and 72 diseases shown 
 4件: CCL2, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: IL6R   D02596   Tocilizumab   16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 1件: JAK1   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 59  Human immunodeficiency virus 1 infection 
 6 genes, 5 drugs (DrugBank) and 64 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 60  Human papillomavirus infection 
 3 genes, 5 drugs (DrugBank) and 38 diseases shown 
 1件: JAK1   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 2件: JAK1, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 61  Human T-cell leukemia virus 1 infection 
 14 genes, 10 drugs (DrugBank) and 70 diseases shown 
 1件: FDPS   D00939   Alendronic acid   7件: 19, 41, 46, 50, 271, 274, 299 
 D07119 
 2件: IL1R1, IL1R2   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 2件: IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: JAK1   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 2件: JAK1, JAK3   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 62  Hypertrophic cardiomyopathy (HCM) 
 6 genes, 4 drugs (DrugBank) and 35 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 2件: IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 63  IL-17 signaling pathway 
 4 genes, 4 drugs (DrugBank) and 34 diseases shown 
 4件: CCL2, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 64  Inflammatory bowel disease (IBD) 
 8 genes, 5 drugs (DrugBank) and 36 diseases shown 
 5件: IL10, IL1A, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 65  Inflammatory mediator regulation of TRP channels 
 2 genes, 3 drugs (DrugBank) and 25 diseases shown 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 66  Influenza A 
 11 genes, 8 drugs (DrugBank) and 42 diseases shown 
 5件: CCL2, IL1A, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: FDPS   D00939   Alendronic acid   7件: 19, 41, 46, 50, 271, 274, 299 
 D07119 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: JAK1, JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 3件: JAK1, JAK2, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 67  Insulin resistance 
 2 genes, 3 drugs (DrugBank) and 34 diseases shown 
 2件: IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 68  Insulin secretion 
 4 genes, 1 drug (DrugBank) and 2 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 69  Intestinal immune network for IgA production 
 4 genes, 2 drugs (DrugBank) and 28 diseases shown 
 2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 2件: IL10, IL6   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 70  JAK-STAT signaling pathway 
 11 genes, 6 drugs (DrugBank) and 35 diseases shown 
 2件: IL10, IL6   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 1件: IL6R   D02596   Tocilizumab   16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 2件: JAK1, JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 4件: JAK1, JAK2, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 71  Kaposi sarcoma-associated herpesvirus infection 
 10 genes, 6 drugs (DrugBank) and 64 diseases shown 
 1件: CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: IL6   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 2件: JAK1, JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 3件: JAK1, JAK2, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 72  Legionellosis 
 5 genes, 5 drugs (DrugBank) and 36 diseases shown 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 3件: IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 73  Leishmaniasis 
 8 genes, 7 drugs (DrugBank) and 39 diseases shown 
 4件: IL10, IL1A, IL1B, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: JAK1, JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 74  Long-term potentiation 
 6 genes, 3 drugs (DrugBank) and 56 diseases shown 
 1件: CACNA1C   D00437   Nifedipine   2件: 50, 81 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 75  Malaria 
 6 genes, 5 drugs (DrugBank) and 36 diseases shown 
 5件: CCL2, IL10, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL12A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 76  MAPK signaling pathway 
 13 genes, 8 drugs (DrugBank) and 68 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 3件: IL1A, IL1B, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 77  Measles 
 9 genes, 6 drugs (DrugBank) and 28 diseases shown 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 3件: IL1A, IL1B, IL6   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 1件: JAK1   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 3件: JAK1, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 78  Metabolic pathways 
 9 genes, 5 drugs (DrugBank) and 46 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 1件: FDPS   D00939   Alendronic acid   7件: 19, 41, 46, 50, 271, 274, 299 
 D07119 
 4件: PDE4A, PDE4B, PDE4C, PDE4D   D08860   Apremilast   5件: 46, 50, 56, 97, 271 
 1件: PDE5A   D02229   Sildenafil   16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 
 D08514 
 1件: TPO   D00401   Methimazole   1件: 50 
 79  Mineral absorption 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: VDR   D01518   Alfacalcidol   6件: 41, 46, 49, 50, 96, 235 
 80  Morphine addiction 
 4 genes, 1 drug (DrugBank) and 5 diseases shown 
 4件: PDE4A, PDE4B, PDE4C, PDE4D   D08860   Apremilast   5件: 46, 50, 56, 97, 271 
 81  mTOR signaling pathway 
 1 gene, 3 drugs (DrugBank) and 34 diseases shown 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 82  Natural killer cell mediated cytotoxicity 
 6 genes, 5 drugs (DrugBank) and 64 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 83  Necroptosis 
 7 genes, 6 drugs (DrugBank) and 38 diseases shown 
 3件: IL1A, IL1B, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: JAK1, JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 4件: JAK1, JAK2, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 84  Neuroactive ligand-receptor interaction 
 5 genes, 6 drugs (DrugBank) and 57 diseases shown 
 1件: CNR2   D11312   Ajulemic acid   3件: 50, 51, 299 
 1件: MC2R   D00146   Corticotropin   12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 1件: NR3C1   D00407   Methylprednisolone   36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 
 D00751 
 D00979 
 D05000 
 D05001 
 D05002 
 D00472   Prednisolone   38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 
 D00980 
 D00981 
 D00982 
 D01239 
 D01998 
 D02156 
 D03301 
 D00473   Prednisone   44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 
 2件: S1PR1, S1PR5   D11460   Siponimod   2件: 13, 50 
 85  NF-kappa B signaling pathway 
 5 genes, 6 drugs (DrugBank) and 44 diseases shown 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 2件: IL1B, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 2件: LTA, TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 1件: TNF   D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 1件: TNFSF11   D03684   Denosumab   7件: 46, 50, 93, 95, 96, 274, 299 
 86  NOD-like receptor signaling pathway 
 6 genes, 6 drugs (DrugBank) and 38 diseases shown 
 4件: CCL2, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: JAK1   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 2件: JAK1, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 87  Non-alcoholic fatty liver disease (NAFLD) 
 5 genes, 5 drugs (DrugBank) and 42 diseases shown 
 4件: IL1A, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL6R   D02596   Tocilizumab   16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 88  Non-small cell lung cancer 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 
 1件: JAK3   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 89  One carbon pool by folate 
 2 genes, 1 drug (DrugBank) and 33 diseases shown 
 2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 90  Oocyte meiosis 
 5 genes, 2 drugs (DrugBank) and 55 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 91  Osteoclast differentiation 
 12 genes, 10 drugs (DrugBank) and 70 diseases shown 
 3件: IL1A, IL1B, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: JAK1   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 2件: JAK1, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 1件: TNFSF11   D03684   Denosumab   7件: 46, 50, 93, 95, 96, 274, 299 
 92  Oxytocin signaling pathway 
 9 genes, 3 drugs (DrugBank) and 56 diseases shown 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00437   Nifedipine   2件: 50, 81 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 93  Pancreatic cancer 
 1 gene, 2 drugs (DrugBank) and 13 diseases shown 
 1件: JAK1   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 94  Parathyroid hormone synthesis, secretion and action 
 6 genes, 3 drugs (DrugBank) and 13 diseases shown 
 4件: PDE4A, PDE4B, PDE4C, PDE4D   D08860   Apremilast   5件: 46, 50, 56, 97, 271 
 1件: TNFSF11   D03684   Denosumab   7件: 46, 50, 93, 95, 96, 274, 299 
 1件: VDR   D01518   Alfacalcidol   6件: 41, 46, 49, 50, 96, 235 
 95  Pathogenic Escherichia coli infection 
 4 genes, 5 drugs (DrugBank) and 42 diseases shown 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 3件: IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL1R1   D02934   Anakinra   17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 96  Pathways in cancer 
 9 genes, 6 drugs (DrugBank) and 35 diseases shown 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 1件: IL6   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 1件: IL6R   D02596   Tocilizumab   16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 2件: JAK1, JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 3件: JAK1, JAK2, JAK3   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 97  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 8 genes, 5 drugs (DrugBank) and 61 diseases shown 
 2件: JAK1, JAK2   D10308   Baricitinib   8件: 41, 46, 49, 50, 93, 107, 265, 325 
 D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: PDCD1   D10316   Nivolumab   10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 98  Pertussis 
 8 genes, 5 drugs (DrugBank) and 36 diseases shown 
 5件: IL10, IL1A, IL1B, IL6, TNF   D01583   Pirfenidone   10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL1B   D09911   Gevokizumab   4件: 41, 50, 56, 269 
 1件: TNF   D00742   Etanercept   15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 99  PI3K-Akt signaling pathway 
 6 genes, 5 drugs (DrugBank) and 31 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, <