Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Acute myeloid leukemia 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
2 Acute myeloid leukemia 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
3 Acute myeloid leukemia 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
4 Acute myeloid leukemia 💬
 1件: RARA 💬 D06543 💬 Vitamin A 3件: 13, 53, 90 💬
5 Adipocytokine signaling pathway 💬
 1件: JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
6 Adipocytokine signaling pathway 💬
 1件: JAK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
7 Adipocytokine signaling pathway 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
8 Adipocytokine signaling pathway 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
9 Adipocytokine signaling pathway 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
10 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 D01450 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
11 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 D07552 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
12 African trypanosomiasis 💬
 2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
13 African trypanosomiasis 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
14 African trypanosomiasis 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
15 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
16 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: JAK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
17 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
18 AGE-RAGE signaling pathway in diabetic complications 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
19 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
20 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
21 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
22 Alcoholic liver disease 💬
 2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
23 Alcoholic liver disease 💬
 1件: IL17A 💬 D11127 💬 Tibulizumab 1件: 53 💬
24 Alcoholic liver disease 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
25 Alcoholic liver disease 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
26 Alcoholic liver disease 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
27 Aldosterone-regulated sodium reabsorption 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
28 Aldosterone-regulated sodium reabsorption 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
29 Allograft rejection 💬
 1件: CD40 💬 D11610 💬 Iscalimab 2件: 49, 53 💬
30 Allograft rejection 💬
 1件: CD40 💬 D11597 💬 Ravagalimab 2件: 53, 97 💬
31 Allograft rejection 💬
 2件: CD80, CD86 💬 D03203 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
32 Allograft rejection 💬
 2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
33 Allograft rejection 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
34 Allograft rejection 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
35 Alzheimer disease 💬
 3件: CHRM1, CHRM3, CHRM5 💬 D00465 💬 Oxybutynin 3件:  6 , 13, 53 💬
36 Alzheimer disease 💬
 3件: CHRM1, CHRM3, CHRM5 💬 D00722 💬 Oxybutynin 3件:  6 , 13, 53 💬
37 Alzheimer disease 💬
 1件: CHRM3 💬 D00661 💬 Cevimeline 1件: 53 💬
38 Alzheimer disease 💬
 1件: CHRM3 💬 D07667 💬 Cevimeline 1件: 53 💬
39 Alzheimer disease 💬
 1件: CHRM3 💬 D00525 💬 Pilocarpine 3件:  6 , 53, 299 💬
40 Alzheimer disease 💬
 1件: CHRM3 💬 D02200 💬 Pilocarpine 3件:  6 , 53, 299 💬
41 Alzheimer disease 💬
 1件: CHRM3 💬 D05478 💬 Pilocarpine 3件:  6 , 53, 299 💬
42 Alzheimer disease 💬
 1件: CHRM3 💬 D01269 💬 Solifenacin 3件:  6 , 13, 53 💬
43 Alzheimer disease 💬
 1件: CHRM3 💬 D08522 💬 Solifenacin 3件:  6 , 13, 53 💬
44 Alzheimer disease 💬
 1件: CHRM3 💬 D00646 💬 Tolterodine 2件: 17, 53 💬
45 Alzheimer disease 💬
 1件: CHRM3 💬 D01148 💬 Tolterodine 2件: 17, 53 💬
46 Alzheimer disease 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
47 Alzheimer disease 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
48 Alzheimer disease 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
49 Alzheimer disease 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
50 Alzheimer disease 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
51 Alzheimer disease 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
52 Alzheimer disease 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
53 Alzheimer disease 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
54 Amoebiasis 💬
 2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
55 Amoebiasis 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
56 Amoebiasis 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
57 Amoebiasis 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
58 Amoebiasis 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
59 Amoebiasis 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
60 Amphetamine addiction 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
61 Amphetamine addiction 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
62 Amphetamine addiction 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
63 AMPK signaling pathway 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
64 AMPK signaling pathway 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
65 Amyotrophic lateral sclerosis 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
66 Amyotrophic lateral sclerosis 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
67 Amyotrophic lateral sclerosis 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
68 Amyotrophic lateral sclerosis 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
69 Amyotrophic lateral sclerosis 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
70 Antifolate resistance 💬
 2件: DHFR, DHFR2 💬 D00142 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
71 Antifolate resistance 💬
 2件: DHFR, DHFR2 💬 D02115 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
72 Antifolate resistance 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
73 Antifolate resistance 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
74 Antifolate resistance 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
75 Antigen processing and presentation 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
76 Antigen processing and presentation 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
77 Apoptosis 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
78 Apoptosis 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
79 Apoptosis 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
80 Apoptosis 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
81 Apoptosis 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
82 Apoptosis - multiple species 💬
 1件: NGFR 💬 D11028 💬 Cenegermin 2件: 53, 90 💬
83 Asthma 💬
 1件: CD40 💬 D11610 💬 Iscalimab 2件: 49, 53 💬
84 Asthma 💬
 1件: CD40 💬 D11597 💬 Ravagalimab 2件: 53, 97 💬
85 Asthma 💬
 1件: FCER1A 💬 D05251 💬 Omalizumab 7件: 46, 53, 65, 98, 162, 226, 299 💬
86 Asthma 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
87 Asthma 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
88 Autoimmune thyroid disease 💬
 1件: CD40 💬 D11610 💬 Iscalimab 2件: 49, 53 💬
89 Autoimmune thyroid disease 💬
 1件: CD40 💬 D11597 💬 Ravagalimab 2件: 53, 97 💬
90 Autoimmune thyroid disease 💬
 2件: CD80, CD86 💬 D03203 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
91 Autophagy - animal 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
92 Autophagy - animal 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
93 Axon guidance 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
94 Axon guidance 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
95 Axon guidance 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
96 Axon guidance 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
97 Axon guidance 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
98 B cell receptor signaling pathway 💬
 1件: BTK 💬 D11478 💬 Branebrutinib 3件: 46, 49, 53 💬
99 B cell receptor signaling pathway 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
100 B cell receptor signaling pathway 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
101 B cell receptor signaling pathway 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
102 B cell receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
103 B cell receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
104 B cell receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
105 Bacterial invasion of epithelial cells 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
106 Bacterial invasion of epithelial cells 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
107 Biosynthesis of cofactors 💬
 2件: DHFR, DHFR2 💬 D00142 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
108 Biosynthesis of cofactors 💬
 2件: DHFR, DHFR2 💬 D02115 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
109 Biosynthesis of cofactors 💬
 1件: DHODH 💬 D00749 💬 Leflunomide 12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
110 Breast cancer 💬
 2件: ESR1, ESR2 💬 D11513 💬 Estetrol 1件: 53 💬
111 Breast cancer 💬
 2件: ESR1, ESR2 💬 D11514 💬 Estetrol 1件: 53 💬
112 Breast cancer 💬
 2件: ESR1, ESR2 💬 D08409 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
113 Breast cancer 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
114 Breast cancer 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
115 C-type lectin receptor signaling pathway 💬
 3件: IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
116 C-type lectin receptor signaling pathway 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
117 C-type lectin receptor signaling pathway 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
118 C-type lectin receptor signaling pathway 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
119 C-type lectin receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
120 C-type lectin receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
121 C-type lectin receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
122 C-type lectin receptor signaling pathway 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
123 C-type lectin receptor signaling pathway 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
124 Calcium signaling pathway 💬
 1件: ADRB3 💬 D09535 💬 Mirabegron 4件:  6 , 13, 53, 226 💬
125 Calcium signaling pathway 💬
 4件: CHRM1, CHRM2, CHRM3, CHRM5 💬 D00465 💬 Oxybutynin 3件:  6 , 13, 53 💬
126 Calcium signaling pathway 💬
 4件: CHRM1, CHRM2, CHRM3, CHRM5 💬 D00722 💬 Oxybutynin 3件:  6 , 13, 53 💬
127 Calcium signaling pathway 💬
 2件: CHRM2, CHRM3 💬 D00525 💬 Pilocarpine 3件:  6 , 53, 299 💬
128 Calcium signaling pathway 💬
 2件: CHRM2, CHRM3 💬 D02200 💬 Pilocarpine 3件:  6 , 53, 299 💬
129 Calcium signaling pathway 💬
 2件: CHRM2, CHRM3 💬 D05478 💬 Pilocarpine 3件:  6 , 53, 299 💬
130 Calcium signaling pathway 💬
 1件: CHRM3 💬 D00661 💬 Cevimeline 1件: 53 💬
131 Calcium signaling pathway 💬
 1件: CHRM3 💬 D07667 💬 Cevimeline 1件: 53 💬
132 Calcium signaling pathway 💬
 1件: CHRM3 💬 D01269 💬 Solifenacin 3件:  6 , 13, 53 💬
133 Calcium signaling pathway 💬
 1件: CHRM3 💬 D08522 💬 Solifenacin 3件:  6 , 13, 53 💬
134 Calcium signaling pathway 💬
 1件: CHRM3 💬 D00646 💬 Tolterodine 2件: 17, 53 💬
135 Calcium signaling pathway 💬
 1件: CHRM3 💬 D01148 💬 Tolterodine 2件: 17, 53 💬
136 Calcium signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
137 Calcium signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
138 Calcium signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
139 cAMP signaling pathway 💬
 2件: CHRM1, CHRM2 💬 D00465 💬 Oxybutynin 3件:  6 , 13, 53 💬
140 cAMP signaling pathway 💬
 2件: CHRM1, CHRM2 💬 D00722 💬 Oxybutynin 3件:  6 , 13, 53 💬
141 cAMP signaling pathway 💬
 1件: CHRM2 💬 D00525 💬 Pilocarpine 3件:  6 , 53, 299 💬
142 cAMP signaling pathway 💬
 1件: CHRM2 💬 D02200 💬 Pilocarpine 3件:  6 , 53, 299 💬
143 cAMP signaling pathway 💬
 1件: CHRM2 💬 D05478 💬 Pilocarpine 3件:  6 , 53, 299 💬
144 cAMP signaling pathway 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
145 cAMP signaling pathway 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
146 cAMP signaling pathway 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
147 Carbohydrate digestion and absorption 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
148 Carbohydrate digestion and absorption 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
149 Cell adhesion molecules 💬
 1件: CD40 💬 D11610 💬 Iscalimab 2件: 49, 53 💬
150 Cell adhesion molecules 💬
 1件: CD40 💬 D11597 💬 Ravagalimab 2件: 53, 97 💬
151 Cell adhesion molecules 💬
 2件: CD80, CD86 💬 D03203 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
152 Cell adhesion molecules 💬
 1件: ITGAL 💬 D03959 💬 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
153 Cell adhesion molecules 💬
 1件: PDCD1 💬 D10316 💬 Nivolumab 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
154 Cellular senescence 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
155 Cellular senescence 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
156 Cellular senescence 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
157 Cellular senescence 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
158 Cellular senescence 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
159 Cellular senescence 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
160 Central carbon metabolism in cancer 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
161 Central carbon metabolism in cancer 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
162 cGMP-PKG signaling pathway 💬
 1件: ADRB3 💬 D09535 💬 Mirabegron 4件:  6 , 13, 53, 226 💬
163 cGMP-PKG signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
164 cGMP-PKG signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
165 cGMP-PKG signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
166 Chagas disease 💬
 2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
167 Chagas disease 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
168 Chagas disease 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
169 Chagas disease 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
170 Chagas disease 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
171 Chagas disease 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
172 Chemical carcinogenesis - reactive oxygen species 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
173 Chemical carcinogenesis - reactive oxygen species 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
174 Chemical carcinogenesis - reactive oxygen species 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
175 Chemical carcinogenesis - receptor activation 💬
 1件: ADRB3 💬 D09535 💬 Mirabegron 4件:  6 , 13, 53, 226 💬
176 Chemical carcinogenesis - receptor activation 💬
 3件: AR, ESR1, ESR2 💬 D08409 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
177 Chemical carcinogenesis - receptor activation 💬
 2件: ESR1, ESR2 💬 D11513 💬 Estetrol 1件: 53 💬
178 Chemical carcinogenesis - receptor activation 💬
 2件: ESR1, ESR2 💬 D11514 💬 Estetrol 1件: 53 💬
179 Chemical carcinogenesis - receptor activation 💬
 1件: JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
180 Chemical carcinogenesis - receptor activation 💬
 1件: JAK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
181 Chemical carcinogenesis - receptor activation 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
182 Chemical carcinogenesis - receptor activation 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
183 Chemical carcinogenesis - receptor activation 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
184 Chemical carcinogenesis - receptor activation 💬
 1件: VDR 💬 D00188 💬 Cholecalciferol 25件:  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
185 Chemokine signaling pathway 💬
 1件: JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
186 Chemokine signaling pathway 💬
 2件: JAK2, JAK3 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
187 Chemokine signaling pathway 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
188 Chemokine signaling pathway 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
189 Chemokine signaling pathway 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
190 Choline metabolism in cancer 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
191 Choline metabolism in cancer 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
192 Cholinergic synapse 💬
 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00465 💬 Oxybutynin 3件:  6 , 13, 53 💬
193 Cholinergic synapse 💬
 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00722 💬 Oxybutynin 3件:  6 , 13, 53 💬
194 Cholinergic synapse 💬
 2件: CHRM2, CHRM3 💬 D00525 💬 Pilocarpine 3件:  6 , 53, 299 💬
195 Cholinergic synapse 💬
 2件: CHRM2, CHRM3 💬 D02200 💬 Pilocarpine 3件:  6 , 53, 299 💬
196 Cholinergic synapse 💬
 2件: CHRM2, CHRM3 💬 D05478 💬 Pilocarpine 3件:  6 , 53, 299 💬
197 Cholinergic synapse 💬
 1件: CHRM3 💬 D00661 💬 Cevimeline 1件: 53 💬
198 Cholinergic synapse 💬
 1件: CHRM3 💬 D07667 💬 Cevimeline 1件: 53 💬
199 Cholinergic synapse 💬
 1件: CHRM3 💬 D01269 💬 Solifenacin 3件:  6 , 13, 53 💬
200 Cholinergic synapse 💬
 1件: CHRM3 💬 D08522 💬 Solifenacin 3件:  6 , 13, 53 💬
201 Cholinergic synapse 💬
 1件: CHRM3 💬 D00646 💬 Tolterodine 2件: 17, 53 💬
202 Cholinergic synapse 💬
 1件: CHRM3 💬 D01148 💬 Tolterodine 2件: 17, 53 💬
203 Cholinergic synapse 💬
 1件: JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
204 Cholinergic synapse 💬
 1件: JAK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
205 Cholinergic synapse 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
206 Cholinergic synapse 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
207 Chronic myeloid leukemia 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
208 Chronic myeloid leukemia 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
209 Chronic myeloid leukemia 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
210 Cocaine addiction 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
211 Colorectal cancer 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
212 Colorectal cancer 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
213 Coronavirus disease - COVID-19 💬
 2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
214 Coronavirus disease - COVID-19 💬
 1件: IL6R 💬 D02596 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
215 Coronavirus disease - COVID-19 💬
 1件: JAK1 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
216 Coronavirus disease - COVID-19 💬
 1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
217 Coronavirus disease - COVID-19 💬
 2件: JAK1, TYK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
218 Coronavirus disease - COVID-19 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
219 Coronavirus disease - COVID-19 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
220 Coronavirus disease - COVID-19 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
221 Coronavirus disease - COVID-19 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
222 Coronavirus disease - COVID-19 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
223 Cytokine-cytokine receptor interaction 💬
 1件: CD40 💬 D11610 💬 Iscalimab 2件: 49, 53 💬
224 Cytokine-cytokine receptor interaction 💬
 1件: CD40 💬 D11597 💬 Ravagalimab 2件: 53, 97 💬
225 Cytokine-cytokine receptor interaction 💬
 3件: IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
226 Cytokine-cytokine receptor interaction 💬
 2件: IL17A, TNFSF13B 💬 D11127 💬 Tibulizumab 1件: 53 💬
227 Cytokine-cytokine receptor interaction 💬
 1件: IL6R 💬 D02596 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
228 Cytokine-cytokine receptor interaction 💬
 2件: LTA, TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
229 Cytokine-cytokine receptor interaction 💬
 1件: LTB 💬 D08866 💬 Baminercept 4件: 13, 46, 53, 97 💬
230 Cytokine-cytokine receptor interaction 💬
 1件: NGFR 💬 D11028 💬 Cenegermin 2件: 53, 90 💬
231 Cytokine-cytokine receptor interaction 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
232 Cytokine-cytokine receptor interaction 💬
 1件: TNFRSF13C 💬 D12151 💬 Ianalumab 5件: 35, 46, 49, 53, 95 💬
233 Cytokine-cytokine receptor interaction 💬
 1件: TNFSF13B 💬 D03068 💬 Belimumab 12件: 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬
234 Cytosolic DNA-sensing pathway 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
235 Diabetic cardiomyopathy 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
236 Diabetic cardiomyopathy 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
237 Diabetic cardiomyopathy 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
238 Dilated cardiomyopathy 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
239 Dilated cardiomyopathy 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
240 Dopaminergic synapse 💬
 3件: PPP3CA, PPP3CB, PPP3CC 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
241 Dopaminergic synapse 💬
 3件: PPP3CA, PPP3CB, PPP3CC 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
242 Dopaminergic synapse 💬
 3件: PPP3CA, PPP3CB, PPP3CC 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
243 Dopaminergic synapse 💬
 1件: SCN1A 💬 D01450 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
244 Dopaminergic synapse 💬
 1件: SCN1A 💬 D07552 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
245 Drug metabolism - other enzymes 💬
 2件: IMPDH1, IMPDH2 💬 D01392 💬 Mizoribine 8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
246 Drug metabolism - other enzymes 💬
 2件: IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil 34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
247 Drug metabolism - other enzymes 💬
 2件: IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil 34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
248 Drug metabolism - other enzymes 💬
 2件: IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil 34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
249 Drug metabolism - other enzymes 💬
 2件: IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid 36件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
250 EGFR tyrosine kinase inhibitor resistance 💬
 1件: IL6R 💬 D02596 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
251 EGFR tyrosine kinase inhibitor resistance 💬
 1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
252 EGFR tyrosine kinase inhibitor resistance 💬
 2件: JAK1, JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
253 EGFR tyrosine kinase inhibitor resistance 💬
 2件: JAK1, JAK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
254 EGFR tyrosine kinase inhibitor resistance 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
255 EGFR tyrosine kinase inhibitor resistance 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
256 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: ESR1 💬 D11513 💬 Estetrol 1件: 53 💬
257 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: ESR1 💬 D11514 💬 Estetrol 1件: 53 💬
258 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: ESR1 💬 D08409 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
259 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: VDR 💬 D00188 💬 Cholecalciferol 25件:  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
260 Endocrine resistance 💬
 2件: ESR1, ESR2 💬 D11513 💬 Estetrol 1件: 53 💬
261 Endocrine resistance 💬
 2件: ESR1, ESR2 💬 D11514 💬 Estetrol 1件: 53 💬
262 Endocrine resistance 💬
 2件: ESR1, ESR2 💬 D08409 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
263 Endocrine resistance 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
264 Endocrine resistance 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
265 Endometrial cancer 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
266 Endometrial cancer 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
267 Epithelial cell signaling in Helicobacter pylori infection 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
268 Epstein-Barr virus infection 💬
 1件: BTK 💬 D11478 💬 Branebrutinib 3件: 46, 49, 53 💬
269 Epstein-Barr virus infection 💬
 1件: CD40 💬 D11610 💬 Iscalimab 2件: 49, 53 💬
270 Epstein-Barr virus infection 💬
 1件: CD40 💬 D11597 💬 Ravagalimab 2件: 53, 97 💬
271 Epstein-Barr virus infection 💬
 1件: ITGAL 💬 D03959 💬 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
272 Epstein-Barr virus infection 💬
 1件: JAK1 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
273 Epstein-Barr virus infection 💬
 1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
274 Epstein-Barr virus infection 💬
 3件: JAK1, JAK3, TYK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
275 Epstein-Barr virus infection 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
276 Epstein-Barr virus infection 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
277 Epstein-Barr virus infection 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
278 Epstein-Barr virus infection 💬
 1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
279 Epstein-Barr virus infection 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
280 ErbB signaling pathway 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
281 ErbB signaling pathway 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
282 Estrogen signaling pathway 💬
 2件: ESR1, ESR2 💬 D11513 💬 Estetrol 1件: 53 💬
283 Estrogen signaling pathway 💬
 2件: ESR1, ESR2 💬 D11514 💬