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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

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111 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  Acute myeloid leukemia 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2  Adipocytokine signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 3  Adrenergic signaling in cardiomyocytes 
 3 genes, 6 drugs (DrugBank) and 26 diseases shown 
 1件: ADRB1   D00601   Metoprolol   7件: 17, 57, 58, 66, 113, 193, 226 
 D02358 
 D05011 
 1件: AGTR1   D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 2件: AGTR1, AGTR2   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 4  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 5 drugs (DrugBank) and 24 diseases shown 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 5  Aldosterone synthesis and secretion 
 2 genes, 6 drugs (DrugBank) and 31 diseases shown 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 1件: MC2R   D00146   Corticotropin   12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 6  Alzheimer disease 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 7  Amphetamine addiction 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 8  AMPK signaling pathway 
 2 genes, 2 drugs (DrugBank) and 45 diseases shown 
 1件: HMGCR   D00434   Simvastatin   19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 9  Amyotrophic lateral sclerosis (ALS) 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 10  Apelin signaling pathway 
 2 genes, 6 drugs (DrugBank) and 50 diseases shown 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 11  Autophagy - animal 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 12  Autophagy - other 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 13  Axon guidance 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 14  B cell receptor signaling pathway 
 6 genes, 2 drugs (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 15  Bile secretion 
 1 gene, 1 drug (DrugBank) and 19 diseases shown 
 1件: HMGCR   D00434   Simvastatin   19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 16  Breast cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 17  C-type lectin receptor signaling pathway 
 6 genes, 2 drugs (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 18  Caffeine metabolism 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: XDH   D00224   Allopurinol   6件: 6, 46, 57, 66, 96, 97 
 19  Calcium signaling pathway 
 7 genes, 7 drugs (DrugBank) and 43 diseases shown 
 1件: ADRB1   D00601   Metoprolol   7件: 17, 57, 58, 66, 113, 193, 226 
 D02358 
 D05011 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 20  cAMP signaling pathway 
 3 genes, 3 drugs (DrugBank) and 19 diseases shown 
 1件: ADRB1   D00601   Metoprolol   7件: 17, 57, 58, 66, 113, 193, 226 
 D02358 
 D05011 
 1件: MC2R   D00146   Corticotropin   12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 1件: PDE4A   D00302   Dipyridamole   5件: 46, 49, 51, 66, 224 
 21  Cellular senescence 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 22  Central carbon metabolism in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 23  cGMP-PKG signaling pathway 
 8 genes, 8 drugs (DrugBank) and 43 diseases shown 
 1件: ADRB1   D00601   Metoprolol   7件: 17, 57, 58, 66, 113, 193, 226 
 D02358 
 D05011 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 1件: PDE5A   D00302   Dipyridamole   5件: 46, 49, 51, 66, 224 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 24  Chagas disease (American trypanosomiasis) 
 1 gene, 4 drugs (DrugBank) and 9 diseases shown 
 1件: ACE   D01069   Cilazapril   1件: 66 
 D07699 
 D00621   Enalapril   4件: 19, 46, 66, 113 
 D07892 
 D00362   Lisinopril   5件: 46, 66, 67, 113, 222 
 D08131 
 D00421   Ramipril   7件: 46, 49, 66, 67, 113, 218, 257 
 25  Choline metabolism in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 26  Colorectal cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 27  Cortisol synthesis and secretion 
 2 genes, 6 drugs (DrugBank) and 31 diseases shown 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 1件: MC2R   D00146   Corticotropin   12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 28  Cushing syndrome 
 2 genes, 6 drugs (DrugBank) and 31 diseases shown 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 1件: MC2R   D00146   Corticotropin   12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 29  Cytokine-cytokine receptor interaction 
 3 genes, 2 drugs (DrugBank) and 10 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 2件: TNFSF13, TNFSF13B   D09704   Atacicept   4件: 13, 46, 49, 66 
 30  Dilated cardiomyopathy (DCM) 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: ADRB1   D00601   Metoprolol   7件: 17, 57, 58, 66, 113, 193, 226 
 D02358 
 D05011 
 31  Dopaminergic synapse 
 3 genes, 1 drug (DrugBank) and 30 diseases shown 
 3件: PPP3CA, PPP3CB, PPP3CC   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 32  Drug metabolism - other enzymes 
 3 genes, 4 drugs (DrugBank) and 39 diseases shown 
 2件: IMPDH1, IMPDH2   D01392   Mizoribine   8件: 46, 49, 51, 53, 66, 94, 222, 224 
 D00752   Mycophenolate mofetil   32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 1件: XDH   D00224   Allopurinol   6件: 6, 46, 57, 66, 96, 97 
 33  EGFR tyrosine kinase inhibitor resistance 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 34  Endocrine and other factor-regulated calcium reabsorption 
 1 gene, 2 drugs (DrugBank) and 10 diseases shown 
 1件: VDR   D00129   Calcitriol   8件: 37, 46, 49, 66, 96, 158, 235, 326 
 D00930   Paricalcitol   3件: 19, 66, 218 
 35  Endocrine resistance 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 36  Endocytosis 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 37  Epstein-Barr virus infection 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 38  ErbB signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 39  Fc epsilon RI signaling pathway 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 40  Fc gamma R-mediated phagocytosis 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 41  Fluid shear stress and atherosclerosis 
 1 gene, 1 drug (DrugBank) and 10 diseases shown 
 1件: NQO1   D00564   Warfarin   10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 
 D01280 
 D08682 
 42  Gap junction 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: ADRB1   D00601   Metoprolol   7件: 17, 57, 58, 66, 113, 193, 226 
 D02358 
 D05011 
 43  Gastric cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 44  Glioma 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 45  Glucagon signaling pathway 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 46  Glutamatergic synapse 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 47  Growth hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 48  Hematopoietic cell lineage 
 2 genes, 2 drugs (DrugBank) and 44 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 1件: MS4A1   D02994   Rituximab   42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 49  Hepatocellular carcinoma 
 2 genes, 2 drugs (DrugBank) and 40 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: NQO1   D00564   Warfarin   10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 
 D01280 
 D08682 
 50  Herpes simplex virus 1 infection 
 2 genes, 2 drugs (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 51  HIF-1 signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 52  Human cytomegalovirus infection 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 53  Human immunodeficiency virus 1 infection 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 54  Human papillomavirus infection 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 55  Human T-cell leukemia virus 1 infection 
 7 genes, 3 drugs (DrugBank) and 32 diseases shown 
 1件: FDPS   D00942   Risedronic acid   7件: 46, 66, 93, 95, 96, 113, 274 
 D03234 
 D08484 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 56  Hypertrophic cardiomyopathy (HCM) 
 1 gene, 4 drugs (DrugBank) and 9 diseases shown 
 1件: ACE   D01069   Cilazapril   1件: 66 
 D07699 
 D00621   Enalapril   4件: 19, 46, 66, 113 
 D07892 
 D00362   Lisinopril   5件: 46, 66, 67, 113, 222 
 D08131 
 D00421   Ramipril   7件: 46, 49, 66, 67, 113, 218, 257 
 57  Influenza A 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: FDPS   D00942   Risedronic acid   7件: 46, 66, 93, 95, 96, 113, 274 
 D03234 
 D08484 
 58  Insulin resistance 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 59  Insulin signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 60  Intestinal immune network for IgA production 
 2 genes, 1 drug (DrugBank) and 4 diseases shown 
 2件: TNFSF13, TNFSF13B   D09704   Atacicept   4件: 13, 46, 49, 66 
 61  JAK-STAT signaling pathway 
 2 genes, 2 drugs (DrugBank) and 39 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 62  Kaposi sarcoma-associated herpesvirus infection 
 7 genes, 3 drugs (DrugBank) and 49 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 63  Long-term potentiation 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 64  Longevity regulating pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 65  Longevity regulating pathway - multiple species 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 66  MAPK signaling pathway 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 67  Measles 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 68  Metabolic pathways 
 10 genes, 9 drugs (DrugBank) and 57 diseases shown 
 1件: DHODH   D00749   Leflunomide   10件: 11, 40, 46, 49, 53, 66, 162, 224, 271, 300 
 1件: FDPS   D00942   Risedronic acid   7件: 46, 66, 93, 95, 96, 113, 274 
 D03234 
 D08484 
 1件: HMGCR   D00434   Simvastatin   19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 2件: IMPDH1, IMPDH2   D01392   Mizoribine   8件: 46, 49, 51, 53, 66, 94, 222, 224 
 D00752   Mycophenolate mofetil   32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 2件: NQO1, VKORC1   D00564   Warfarin   10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 
 D01280 
 D08682 
 2件: PDE4A, PDE5A   D00302   Dipyridamole   5件: 46, 49, 51, 66, 224 
 1件: XDH   D00224   Allopurinol   6件: 6, 46, 57, 66, 96, 97 
 69  MicroRNAs in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 70  Mineral absorption 
 1 gene, 2 drugs (DrugBank) and 10 diseases shown 
 1件: VDR   D00129   Calcitriol   8件: 37, 46, 49, 66, 96, 158, 235, 326 
 D00930   Paricalcitol   3件: 19, 66, 218 
 71  Morphine addiction 
 1 gene, 1 drug (DrugBank) and 5 diseases shown 
 1件: PDE4A   D00302   Dipyridamole   5件: 46, 49, 51, 66, 224 
 72  mTOR signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 73  Natural killer cell mediated cytotoxicity 
 6 genes, 2 drugs (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 74  Neuroactive ligand-receptor interaction 
 5 genes, 11 drugs (DrugBank) and 71 diseases shown 
 1件: ADRB1   D00601   Metoprolol   7件: 17, 57, 58, 66, 113, 193, 226 
 D02358 
 D05011 
 1件: AGTR1   D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 2件: AGTR1, AGTR2   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 1件: MC2R   D00146   Corticotropin   12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 1件: NR3C1   D00246   Budesonide   10件: 66, 85, 93, 94, 95, 96, 97, 98, 228, 299 
 D00407   Methylprednisolone   36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 
 D00751 
 D00979 
 D05000 
 D05001 
 D05002 
 D00472   Prednisolone   38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 
 D00980 
 D00981 
 D00982 
 D01239 
 D01998 
 D02156 
 D03301 
 D00473   Prednisone   44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 
 75  NF-kappa B signaling pathway 
 2 genes, 2 drugs (DrugBank) and 5 diseases shown 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 1件: TNFSF13B   D09704   Atacicept   4件: 13, 46, 49, 66 
 76  Oocyte meiosis 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 77  Osteoclast differentiation 
 6 genes, 2 drugs (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 78  Oxytocin signaling pathway 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 79  Pancreatic cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 80  Parathyroid hormone synthesis, secretion and action 
 2 genes, 3 drugs (DrugBank) and 12 diseases shown 
 1件: PDE4A   D00302   Dipyridamole   5件: 46, 49, 51, 66, 224 
 1件: VDR   D00129   Calcitriol   8件: 37, 46, 49, 66, 96, 158, 235, 326 
 D00930   Paricalcitol   3件: 19, 66, 218 
 81  Pathways in cancer 
 4 genes, 8 drugs (DrugBank) and 55 diseases shown 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: NQO1   D00564   Warfarin   10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 
 D01280 
 D08682 
 82  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 6 genes, 2 drugs (DrugBank) and 49 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 83  Peroxisome 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: XDH   D00224   Allopurinol   6件: 6, 46, 57, 66, 96, 97 
 84  Phospholipase D signaling pathway 
 3 genes, 7 drugs (DrugBank) and 50 diseases shown 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 85  PI3K-Akt signaling pathway 
 3 genes, 3 drugs (DrugBank) and 39 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 86  Platelet activation 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 87  Prostate cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 88  Proteasome 
 1 gene, 1 drug (DrugBank) and 13 diseases shown 
 1件: PSMB5   D03150   Bortezomib   13件: 11, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 288, 331 
 89  Proteoglycans in cancer 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 90  Purine metabolism 
 5 genes, 5 drugs (DrugBank) and 39 diseases shown 
 2件: IMPDH1, IMPDH2   D01392   Mizoribine   8件: 46, 49, 51, 53, 66, 94, 222, 224 
 D00752   Mycophenolate mofetil   32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 2件: PDE4A, PDE5A   D00302   Dipyridamole   5件: 46, 49, 51, 66, 224 
 1件: XDH   D00224   Allopurinol   6件: 6, 46, 57, 66, 96, 97 
 91  Pyrimidine metabolism 
 1 gene, 1 drug (DrugBank) and 10 diseases shown 
 1件: DHODH   D00749   Leflunomide   10件: 11, 40, 46, 49, 53, 66, 162, 224, 271, 300 
 92  Regulation of lipolysis in adipocytes 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: ADRB1   D00601   Metoprolol   7件: 17, 57, 58, 66, 113, 193, 226 
 D02358 
 D05011 
 93  Renin secretion 
 9 genes, 12 drugs (DrugBank) and 44 diseases shown 
 1件: ACE   D01069   Cilazapril   1件: 66 
 D07699 
 D00621   Enalapril   4件: 19, 46, 66, 113 
 D07892 
 D00362   Lisinopril   5件: 46, 66, 67, 113, 222 
 D08131 
 D00421   Ramipril   7件: 46, 49, 66, 67, 113, 218, 257 
 1件: ADRB1   D00601   Metoprolol   7件: 17, 57, 58, 66, 113, 193, 226 
 D02358 
 D05011 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: REN   D03208   Aliskiren   3件: 66, 167, 222 
 94  Renin-angiotensin system 
 4 genes, 10 drugs (DrugBank) and 26 diseases shown 
 1件: ACE   D01069   Cilazapril   1件: 66 
 D07699 
 D00621   Enalapril   4件: 19, 46, 66, 113 
 D07892 
 D00362   Lisinopril   5件: 46, 66, 67, 113, 222 
 D08131 
 D00421   Ramipril   7件: 46, 49, 66, 67, 113, 218, 257 
 1件: AGTR1   D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 2件: AGTR1, AGTR2   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 1件: REN   D03208   Aliskiren   3件: 66, 167, 222 
 95  Rheumatoid arthritis 
 2 genes, 1 drug (DrugBank) and 4 diseases shown 
 2件: TNFSF13, TNFSF13B   D09704   Atacicept   4件: 13, 46, 49, 66 
 96  Salivary secretion 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: ADRB1   D00601   Metoprolol   7件: 17, 57, 58, 66, 113, 193, 226 
 D02358 
 D05011 
 97  Shigellosis 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 98  T cell receptor signaling pathway 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 99  Terpenoid backbone biosynthesis 
 2 genes, 2 drugs (DrugBank) and 24 diseases shown 
 1件: FDPS   D00942   Risedronic acid   7件: 46, 66, 93, 95, 96, 113, 274 
 D03234 
 D08484 
 1件: HMGCR   D00434   Simvastatin   19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 100  Th1 and Th2 cell differentiation 
 6 genes, 2 drugs (DrugBank) and 30 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 101  Th17 cell differentiation 
 7 genes, 3 drugs (DrugBank) and 49 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 102  Thermogenesis 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 103  Thyroid hormone signaling pathway 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 104  Tuberculosis 
 7 genes, 4 drugs (DrugBank) and 35 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 1件: VDR   D00129   Calcitriol   8件: 37, 46, 49, 66, 96, 158, 235, 326 
 D00930   Paricalcitol   3件: 19, 66, 218 
 105  Type II diabetes mellitus 
 1 gene, 1 drug (DrugBank) and 36 diseases shown 
 1件: MTOR   D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 106  Ubiquinone and other terpenoid-quinone biosynthesis 
 2 genes, 1 drug (DrugBank) and 10 diseases shown 
 2件: NQO1, VKORC1   D00564   Warfarin   10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 
 D01280 
 D08682 
 107  Vascular smooth muscle contraction 
 1 gene, 5 drugs (DrugBank) and 24 diseases shown 
 1件: AGTR1   D00150   Angiotensin II   7件: 17, 19, 46, 66, 86, 222, 224 
 D02014 
 D00523   Irbesartan   4件: 66, 167, 168, 222 
 D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 D00627   Telmisartan   2件: 66, 67 
 D00400   Valsartan   6件: 57, 58, 66, 75, 218, 222 
 108  VEGF signaling pathway 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 109  Viral carcinogenesis 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 
 1件: SYK   D09347   Fostamatinib   4件: 46, 49, 61, 66 
 110  Viral protein interaction with cytokine and cytokine receptor 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: IL2RA   D03058   Basiliximab   7件: 2, 50, 65, 66, 97, 222, 228 
 111  Wnt signaling pathway 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 

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