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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

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17 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  Aldosterone synthesis and secretion 
 1 gene, 1 drug (DrugBank) and 5 diseases shown 
 1件: MC2R   D00284   Tetracosactide   5件: 78, 83, 113, 145, 222 
 2  Breast cancer 
 2 genes, 1 drug (DrugBank) and 6 diseases shown 
 2件: ESR1, ESR2   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 3  cAMP signaling pathway 
 1 gene, 1 drug (DrugBank) and 5 diseases shown 
 1件: MC2R   D00284   Tetracosactide   5件: 78, 83, 113, 145, 222 
 4  Cortisol synthesis and secretion 
 1 gene, 1 drug (DrugBank) and 5 diseases shown 
 1件: MC2R   D00284   Tetracosactide   5件: 78, 83, 113, 145, 222 
 5  Cushing syndrome 
 1 gene, 1 drug (DrugBank) and 5 diseases shown 
 1件: MC2R   D00284   Tetracosactide   5件: 78, 83, 113, 145, 222 
 6  Endocrine and other factor-regulated calcium reabsorption 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: ESR1   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 7  Endocrine resistance 
 2 genes, 1 drug (DrugBank) and 6 diseases shown 
 2件: ESR1, ESR2   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 8  Estrogen signaling pathway 
 2 genes, 1 drug (DrugBank) and 6 diseases shown 
 2件: ESR1, ESR2   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 9  GnRH secretion 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: ESR2   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 10  Hematopoietic cell lineage 
 1 gene, 1 drug (DrugBank) and 42 diseases shown 
 1件: MS4A1   D02994   Rituximab   42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 11  Neuroactive ligand-receptor interaction 
 2 genes, 7 drugs (DrugBank) and 48 diseases shown 
 1件: MC2R   D00284   Tetracosactide   5件: 78, 83, 113, 145, 222 
 1件: NR3C1   D00292   Dexamethasone   20件: 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 
 D00975 
 D01510 
 D01615 
 D01632 
 D01948 
 D02174 
 D02591 
 D02592 
 D00088   Hydrocortisone   8件: 6, 53, 75, 78, 81, 83, 97, 299 
 D00165   Hydrocortisone acetate   8件: 6, 53, 75, 78, 81, 83, 97, 299 
 D00976   Hydrocortisone cypionate   2件: 81, 83 
 D01442   Hydrocortisone succinate   3件: 6, 81, 83 
 D00407   Methylprednisolone   36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 
 D00751 
 D00979 
 D05000 
 D05001 
 D05002 
 12  Oocyte meiosis 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: AR   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 13  Pathways in cancer 
 3 genes, 1 drug (DrugBank) and 6 diseases shown 
 3件: AR, ESR1, ESR2   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 14  Prolactin signaling pathway 
 2 genes, 1 drug (DrugBank) and 6 diseases shown 
 2件: ESR1, ESR2   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 15  Prostate cancer 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: AR   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 16  Proteoglycans in cancer 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: ESR1   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 17  Thyroid hormone signaling pathway 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 
 1件: ESR1   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 

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