Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Acute myeloid leukemia 💬
 4件: BRAF, FLT3, KIT, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
2 Acute myeloid leukemia 💬
 1件: KIT 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
3 Acute myeloid leukemia 💬
 1件: KIT 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
4 Acute myeloid leukemia 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
5 Adherens junction 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
6 Adipocytokine signaling pathway 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
7 Adipocytokine signaling pathway 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
8 Adrenergic signaling in cardiomyocytes 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬 💬
9 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬 💬
10 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬 💬
11 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
12 Adrenergic signaling in cardiomyocytes 💬
 2件: AGTR1, AGTR2 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
13 Adrenergic signaling in cardiomyocytes 💬
 2件: AGTR1, AGTR2 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
14 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
15 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
16 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Lidocaine 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬
17 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Lidocaine hydrochloride monohydrate 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬
18 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
19 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
20 Alcoholic liver disease 💬
 1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
21 Alcoholic liver disease 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
22 Alcoholism 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
23 Alcoholism 💬
 1件: DRD2 💬 Lisuride 💬 Lisuride 2件:  6 , 86 💬 💬
24 Alcoholism 💬
 1件: DRD2 💬 Terguride 💬 Terguride 2件: 51, 86 💬 💬
25 Aldosterone synthesis and secretion 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
26 Aldosterone synthesis and secretion 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
27 Aldosterone synthesis and secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
28 Aldosterone synthesis and secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
29 Aldosterone-regulated sodium reabsorption 💬
 1件: NR3C2 💬 Spironolactone 💬 Spironolactone 8件: 46, 58, 67, 86, 113, 210, 218, 225 💬 💬
30 Alzheimer disease 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
31 Alzheimer disease 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
32 Alzheimer disease 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
33 Alzheimer disease 💬
 1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
34 Alzheimer disease 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
35 Alzheimer disease 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
36 Alzheimer disease 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
37 Amoebiasis 💬
 2件: IL1R1, IL1R2 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬
38 Amphetamine addiction 💬
 2件: CACNA1C, CACNA1D 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
39 Amphetamine addiction 💬
 2件: CACNA1C, CACNA1D 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
40 AMPK signaling pathway 💬
 1件: ADRA1A 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬 💬
41 AMPK signaling pathway 💬
 1件: HMGCR 💬 Simvastatin 💬 Simvastatin 21件:  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬
42 AMPK signaling pathway 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
43 AMPK signaling pathway 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
44 AMPK signaling pathway 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
45 Amyotrophic lateral sclerosis 💬
 1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
46 Amyotrophic lateral sclerosis 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
47 Apelin signaling pathway 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
48 Apelin signaling pathway 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
49 Apelin signaling pathway 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
50 Apelin signaling pathway 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
51 Apelin signaling pathway 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
52 Apoptosis 💬
 1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
53 Apoptosis 💬
 2件: PARP1, PARP2 💬 Olaparib 💬 Olaparib 2件: 86, 285 💬 💬
54 Apoptosis 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
55 Arachidonic acid metabolism 💬
 2件: PTGS1, PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
56 Arachidonic acid metabolism 💬
 2件: PTGS1, PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
57 Arrhythmogenic right ventricular cardiomyopathy 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
58 Arrhythmogenic right ventricular cardiomyopathy 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
59 Autophagy - animal 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
60 Autophagy - animal 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
61 Autophagy - animal 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
62 Autophagy - other 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
63 Axon guidance 💬
 1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
64 Axon guidance 💬
 1件: ABL1 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
65 Axon guidance 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
66 B cell receptor signaling pathway 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
67 Base excision repair 💬
 2件: PARP1, PARP2 💬 Olaparib 💬 Olaparib 2件: 86, 285 💬 💬
68 Bile secretion 💬
 1件: CA2 💬 Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 💬
69 Bile secretion 💬
 1件: HMGCR 💬 Simvastatin 💬 Simvastatin 21件:  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬
70 Biosynthesis of cofactors 💬
 2件: NQO1, VKORC1 💬 Warfarin 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬
71 Bladder cancer 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
72 Bladder cancer 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
73 Breast cancer 💬
 4件: BRAF, FLT4, KIT, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
74 Breast cancer 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
75 Breast cancer 💬
 2件: ESR1, ESR2 💬 Fulvestrant 💬 Fulvestrant 2件: 49, 86 💬 💬
76 Breast cancer 💬
 2件: ESR1, ESR2 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬 💬
77 Breast cancer 💬
 1件: KIT 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
78 Breast cancer 💬
 1件: KIT 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
79 Breast cancer 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
80 C-type lectin receptor signaling pathway 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
81 C-type lectin receptor signaling pathway 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
82 C-type lectin receptor signaling pathway 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
83 Calcium signaling pathway 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬 💬
84 Calcium signaling pathway 💬
 1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬 💬
85 Calcium signaling pathway 💬
 1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬 💬
86 Calcium signaling pathway 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
87 Calcium signaling pathway 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
88 Calcium signaling pathway 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
89 Calcium signaling pathway 💬
 1件: AVPR1A 💬 Conivaptan 💬 Conivaptan 1件: 86 💬 💬
90 Calcium signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
91 Calcium signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
92 Calcium signaling pathway 💬
 1件: EDNRA 💬 Ambrisentan 💬 Ambrisentan 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬
93 Calcium signaling pathway 💬
 1件: EDNRA 💬 Sitaxentan 💬 Sitaxentan 1件: 86 💬 💬
94 Calcium signaling pathway 💬
 2件: EDNRA, EDNRB 💬 Bosentan 💬 Bosentan 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬
95 Calcium signaling pathway 💬
 2件: EDNRA, EDNRB 💬 Bosentan 💬 Bosentan 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬
96 Calcium signaling pathway 💬
 2件: EDNRA, EDNRB 💬 Macitentan 💬 Macitentan 5件: 51, 85, 86, 88, 210 💬 💬
97 Calcium signaling pathway 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
98 Calcium signaling pathway 💬
 4件: FLT4, KDR, PDGFRB, RET 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
99 Calcium signaling pathway 💬
 1件: HRH1 💬 Diphenhydramine 💬 Diphenhydramine 8件: 11, 13, 49, 51, 70, 86, 222, 256 💬 💬
100 Calcium signaling pathway 💬
 1件: HRH2 💬 Famotidine 💬 Famotidine 6件:  6 , 46, 61, 86, 98, 107 💬 💬
101 Calcium signaling pathway 💬
 1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
102 Calcium signaling pathway 💬
 2件: PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
103 cAMP signaling pathway 💬
 1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬 💬
104 cAMP signaling pathway 💬
 1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬 💬
105 cAMP signaling pathway 💬
 2件: ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬 💬
106 cAMP signaling pathway 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
107 cAMP signaling pathway 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
108 cAMP signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
109 cAMP signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
110 cAMP signaling pathway 💬
 1件: DRD2 💬 Lisuride 💬 Lisuride 2件:  6 , 86 💬 💬
111 cAMP signaling pathway 💬
 1件: DRD2 💬 Terguride 💬 Terguride 2件: 51, 86 💬 💬
112 cAMP signaling pathway 💬
 1件: EDNRA 💬 Ambrisentan 💬 Ambrisentan 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬
113 cAMP signaling pathway 💬
 1件: EDNRA 💬 Bosentan 💬 Bosentan 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬
114 cAMP signaling pathway 💬
 1件: EDNRA 💬 Bosentan 💬 Bosentan 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬
115 cAMP signaling pathway 💬
 1件: EDNRA 💬 Macitentan 💬 Macitentan 5件: 51, 85, 86, 88, 210 💬 💬
116 cAMP signaling pathway 💬
 1件: EDNRA 💬 Sitaxentan 💬 Sitaxentan 1件: 86 💬 💬
117 Carbohydrate digestion and absorption 💬
 1件: CACNA1D 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
118 Carbohydrate digestion and absorption 💬
 1件: CACNA1D 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
119 Carbohydrate digestion and absorption 💬
 2件: TAS1R2, TAS1R3 💬 Aspartame 💬 Aspartame 4件:  6 , 13, 67, 86 💬 💬
120 Cardiac muscle contraction 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
121 Cardiac muscle contraction 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
122 Cell cycle 💬
 1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
123 Cell cycle 💬
 1件: ABL1 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
124 Cellular senescence 💬
 1件: CACNA1D 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
125 Cellular senescence 💬
 1件: CACNA1D 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
126 Cellular senescence 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
127 Cellular senescence 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
128 Central carbon metabolism in cancer 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
129 Central carbon metabolism in cancer 💬
 5件: FLT3, KIT, PDGFRB, RAF1, RET 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
130 Central carbon metabolism in cancer 💬
 2件: KIT, PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
131 Central carbon metabolism in cancer 💬
 3件: KIT, PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
132 Central carbon metabolism in cancer 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
133 cGMP-PKG signaling pathway 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬 💬
134 cGMP-PKG signaling pathway 💬
 1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬 💬
135 cGMP-PKG signaling pathway 💬
 1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬 💬
136 cGMP-PKG signaling pathway 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
137 cGMP-PKG signaling pathway 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
138 cGMP-PKG signaling pathway 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
139 cGMP-PKG signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
140 cGMP-PKG signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
141 cGMP-PKG signaling pathway 💬
 1件: EDNRA 💬 Ambrisentan 💬 Ambrisentan 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬
142 cGMP-PKG signaling pathway 💬
 1件: EDNRA 💬 Sitaxentan 💬 Sitaxentan 1件: 86 💬 💬
143 cGMP-PKG signaling pathway 💬
 2件: EDNRA, EDNRB 💬 Bosentan 💬 Bosentan 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬
144 cGMP-PKG signaling pathway 💬
 2件: EDNRA, EDNRB 💬 Bosentan 💬 Bosentan 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬
145 cGMP-PKG signaling pathway 💬
 2件: EDNRA, EDNRB 💬 Macitentan 💬 Macitentan 5件: 51, 85, 86, 88, 210 💬 💬
146 cGMP-PKG signaling pathway 💬
 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬 💬
147 cGMP-PKG signaling pathway 💬
 1件: PDE5A 💬 Sildenafil 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 💬
148 cGMP-PKG signaling pathway 💬
 1件: PDE5A 💬 Tadalafil 💬 Tadalafil 7件:  6 , 51, 75, 84, 86, 113, 210 💬 💬
149 cGMP-PKG signaling pathway 💬
 1件: PDE5A 💬 Udenafil 💬 Udenafil 2件: 86, 210 💬 💬
150 cGMP-PKG signaling pathway 💬
 1件: PDE5A 💬 Vardenafil 💬 Vardenafil 3件: 13, 86, 299 💬 💬
151 cGMP-PKG signaling pathway 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
152 Chagas disease 💬
 1件: ACE 💬 Captopril 💬 Captopril 8件:  6 , 17, 46, 86, 96, 97, 107, 271 💬 💬
153 Chemical carcinogenesis - DNA adducts 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
154 Chemical carcinogenesis - DNA adducts 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
155 Chemical carcinogenesis - reactive oxygen species 💬
 1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
156 Chemical carcinogenesis - reactive oxygen species 💬
 1件: ABL1 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
157 Chemical carcinogenesis - reactive oxygen species 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
158 Chemical carcinogenesis - reactive oxygen species 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
159 Chemical carcinogenesis - reactive oxygen species 💬
 1件: KEAP1 💬 Dimethyl fumarate 💬 Dimethyl fumarate 5件: 13, 49, 51, 86, 296 💬 💬
160 Chemical carcinogenesis - reactive oxygen species 💬
 1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
161 Chemical carcinogenesis - reactive oxygen species 💬
 1件: NQO1 💬 Warfarin 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬
162 Chemical carcinogenesis - receptor activation 💬
 1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬 💬
163 Chemical carcinogenesis - receptor activation 💬
 1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬 💬
164 Chemical carcinogenesis - receptor activation 💬
 2件: ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬 💬
165 Chemical carcinogenesis - receptor activation 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
166 Chemical carcinogenesis - receptor activation 💬
 3件: AR, ESR1, ESR2 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬 💬
167 Chemical carcinogenesis - receptor activation 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
168 Chemical carcinogenesis - receptor activation 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
169 Chemical carcinogenesis - receptor activation 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
170 Chemical carcinogenesis - receptor activation 💬
 2件: ESR1, ESR2 💬 Fulvestrant 💬 Fulvestrant 2件: 49, 86 💬 💬
171 Chemical carcinogenesis - receptor activation 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
172 Chemical carcinogenesis - receptor activation 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
173 Chemokine signaling pathway 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
174 Choline metabolism in cancer 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
175 Choline metabolism in cancer 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
176 Choline metabolism in cancer 💬
 1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
177 Choline metabolism in cancer 💬
 2件: PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
178 Choline metabolism in cancer 💬
 2件: PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
179 Cholinergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
180 Cholinergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
181 Chronic myeloid leukemia 💬
 1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
182 Chronic myeloid leukemia 💬
 1件: ABL1 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
183 Chronic myeloid leukemia 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
184 Circadian entrainment 💬
 2件: CACNA1C, CACNA1D 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
185 Circadian entrainment 💬
 2件: CACNA1C, CACNA1D 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
186 Circadian entrainment 💬
 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬 💬
187 Circadian rhythm 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
188 Cocaine addiction 💬
 1件: DRD2 💬 Lisuride 💬 Lisuride 2件:  6 , 86 💬 💬
189 Cocaine addiction 💬
 1件: DRD2 💬 Terguride 💬 Terguride 2件: 51, 86 💬 💬
190 Collecting duct acid secretion 💬
 2件: ATP4A, ATP4B 💬 Esomeprazole 💬 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 💬
191 Collecting duct acid secretion 💬
 1件: CA2 💬 Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 💬
192 Colorectal cancer 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
193 Colorectal cancer 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
194 Colorectal cancer 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
195 Coronavirus disease - COVID-19 💬
 1件: ACE 💬 Captopril 💬 Captopril 8件:  6 , 17, 46, 86, 96, 97, 107, 271 💬 💬
196 Coronavirus disease - COVID-19 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
197 Coronavirus disease - COVID-19 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
198 Coronavirus disease - COVID-19 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
199 Coronavirus disease - COVID-19 💬
 1件: IL6R 💬 Satralizumab 💬 Satralizumab 3件: 11, 13, 86 💬 💬
200 Coronavirus disease - COVID-19 💬
 1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬
201 Cortisol synthesis and secretion 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
202 Cortisol synthesis and secretion 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
203 Cortisol synthesis and secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
204 Cortisol synthesis and secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
205 Cushing syndrome 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
206 Cushing syndrome 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
207 Cushing syndrome 💬
 1件: BRAF 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
208 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
209 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
210 Cushing syndrome 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
211 Cytokine-cytokine receptor interaction 💬
 1件: ACVR2A 💬 Sotatercept 💬 Sotatercept 2件: 86, 284 💬 💬
212 Cytokine-cytokine receptor interaction 💬
 2件: IL1R1, IL1R2 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬
213 Cytokine-cytokine receptor interaction 💬
 1件: IL6R 💬 Satralizumab 💬 Satralizumab 3件: 11, 13, 86 💬 💬
214 Cytokine-cytokine receptor interaction 💬
 1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬
215 Cytokine-cytokine receptor interaction 💬
 1件: PRL 💬 Terguride 💬 Terguride 2件: 51, 86 💬 💬
216 Diabetic cardiomyopathy 💬
 1件: ACE 💬 Captopril 💬 Captopril 8件:  6 , 17, 46, 86, 96, 97, 107, 271 💬 💬
217 Diabetic cardiomyopathy 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
218 Diabetic cardiomyopathy 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬 💬
219 Diabetic cardiomyopathy 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
220 Diabetic cardiomyopathy 💬
 1件: PARP1 💬 Olaparib 💬 Olaparib 2件: 86, 285 💬 💬
221 Diabetic cardiomyopathy 💬
 3件: PDK2, PDK3, PDK4 💬 Sodium dichloroacetate 💬 Sodium dichloroacetate 1件: 86 💬 💬
222 Dilated cardiomyopathy 💬
 1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬 💬
223 Dilated cardiomyopathy 💬
 1件: ADRB1 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬 💬
224 Dilated cardiomyopathy 💬
 1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬 💬
225 Dilated cardiomyopathy 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
226 Dilated cardiomyopathy 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
227 Dopaminergic synapse 💬
 2件: CACNA1C, CACNA1D 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
228 Dopaminergic synapse 💬
 2件: CACNA1C, CACNA1D 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
229 Dopaminergic synapse 💬
 1件: DRD2 💬 Terguride 💬 Terguride 2件: 51, 86 💬 💬
230 Dopaminergic synapse 💬
 3件: DRD2, DRD3, DRD4 💬 Lisuride 💬 Lisuride 2件:  6 , 86 💬 💬
231 Dopaminergic synapse 💬
 1件: SCN1A 💬 Lidocaine 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬
232 Dopaminergic synapse 💬
 1件: SCN1A 💬 Lidocaine hydrochloride monohydrate 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬
233 Drug metabolism - other enzymes 💬
 1件: RRM2 💬 Hydroxyurea 💬 Hydroxyurea 8件:  3 , 13, 19, 20, 65, 85, 86, 284 💬 💬
234 EGFR tyrosine kinase inhibitor resistance 💬
 4件: BRAF, KDR, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
235 EGFR tyrosine kinase inhibitor resistance 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
236 EGFR tyrosine kinase inhibitor resistance 💬
 1件: IL6R 💬 Satralizumab 💬 Satralizumab 3件: 11, 13, 86 💬 💬
237 EGFR tyrosine kinase inhibitor resistance 💬
 1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬
238 EGFR tyrosine kinase inhibitor resistance 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
239 EGFR tyrosine kinase inhibitor resistance 💬
 1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
240 EGFR tyrosine kinase inhibitor resistance 💬
 2件: PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
241 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 2件: 49, 86 💬 💬
242 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬 💬
243 Endocrine resistance 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
244 Endocrine resistance 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
245 Endocrine resistance 💬
 2件: ESR1, ESR2 💬 Fulvestrant 💬 Fulvestrant 2件: 49, 86 💬 💬
246 Endocrine resistance 💬
 2件: ESR1, ESR2 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬 💬
247 Endocrine resistance 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
248 Endocytosis 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
249 Endocytosis 💬
 1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
250 Endocytosis 💬
 1件: PDGFRA 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
251 Endometrial cancer 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
252 Endometrial cancer 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
253 Epithelial cell signaling in Helicobacter pylori infection 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
254 ErbB signaling pathway 💬
 1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
255 ErbB signaling pathway 💬
 1件: ABL1 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
256 ErbB signaling pathway 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
257 ErbB signaling pathway 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
258 ErbB signaling pathway 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
259 Estrogen signaling pathway 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
260 Estrogen signaling pathway 💬
 2件: ESR1, ESR2 💬 Fulvestrant 💬 Fulvestrant 2件: 49, 86 💬 💬
261 Estrogen signaling pathway 💬
 2件: ESR1, ESR2 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬 💬
262 Estrogen signaling pathway 💬
 1件: OPRM1 💬 Morphine 💬 Morphine 5件: 36, 46, 70, 85, 86 💬 💬
263 Estrogen signaling pathway 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
264 Fc epsilon RI signaling pathway 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
265 Fc gamma R-mediated phagocytosis 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
266 Fluid shear stress and atherosclerosis 💬
 1件: ACVR2A 💬 Sotatercept 💬 Sotatercept 2件: 86, 284 💬 💬
267 Fluid shear stress and atherosclerosis 💬
 2件: IL1R1, IL1R2 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬
268 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
269 Fluid shear stress and atherosclerosis 💬
 1件: KEAP1 💬 Dimethyl fumarate 💬 Dimethyl fumarate 5件: 13, 49, 51, 86, 296 💬 💬
270 Fluid shear stress and atherosclerosis 💬
 1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
271 Fluid shear stress and atherosclerosis 💬
 1件: NQO1 💬 Warfarin 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬
272 Fluid shear stress and atherosclerosis 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
273 Focal adhesion 💬
 5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
274 Focal adhesion 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
275 Focal adhesion 💬
 1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
276 Focal adhesion 💬
 2件: PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
277 FoxO signaling pathway 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
278 FoxO signaling pathway 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
279 FoxO signaling pathway 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
280 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
281 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
282 Gap junction 💬
 1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬 💬
283 Gap junction 💬
 1件: ADRB1 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬 💬
284 Gap junction 💬
 1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬 💬
285 Gap junction 💬
 1件: DRD2 💬 Lisuride 💬 Lisuride 2件:  6 , 86 💬 💬
286 Gap junction 💬
 1件: DRD2 💬 Terguride 💬 Terguride 2件: 51, 86 💬 💬
287 Gap junction 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
288 Gap junction 💬
 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬 💬
289 Gap junction 💬
 1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
290 Gap junction 💬
 2件: PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
291 Gap junction 💬
 2件: PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
292 Gastric acid secretion 💬
 2件: ATP4A, ATP4B 💬 Esomeprazole 💬 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 💬
293 Gastric acid secretion 💬
 1件: CA2 💬 Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 💬
294 Gastric acid secretion 💬
 1件: HRH2 💬 Famotidine 💬 Famotidine 6件:  6 , 46, 61, 86, 98, 107 💬 💬
295 Gastric cancer 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
296 Gastric cancer 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
297 Gastric cancer 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
298 Glioma 💬
 3件: BRAF, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
299 Glioma 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
300 Glioma 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
301 Glioma 💬
 1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
302 Glioma 💬
 2件: PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
303 Glucagon signaling pathway 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
304 Glutamatergic synapse 💬
 2件: CACNA1C, CACNA1D 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
305 Glutamatergic synapse 💬
 2件: CACNA1C, CACNA1D 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
306 Glutathione metabolism 💬
 1件: ANPEP 💬 Ubenimex 💬 Ubenimex 1件: 86 💬 💬
307 Glutathione metabolism 💬
 1件: RRM2 💬 Hydroxyurea 💬 Hydroxyurea 8件:  3 , 13, 19, 20, 65, 85, 86, 284 💬 💬
308 GnRH secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
309 GnRH secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
310 GnRH secretion 💬
 1件: ESR2 💬 Fulvestrant 💬 Fulvestrant 2件: 49, 86 💬 💬
311 GnRH secretion 💬
 1件: ESR2 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬 💬
312 GnRH secretion 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
313 GnRH signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
314 GnRH signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
315 GnRH signaling pathway 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
316 GnRH signaling pathway 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
317 Growth hormone synthesis, secretion and action 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
318 Growth hormone synthesis, secretion and action 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
319 Growth hormone synthesis, secretion and action 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
320 Growth hormone synthesis, secretion and action 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
321 Hematopoietic cell lineage 💬
 1件: ANPEP 💬 Ubenimex 💬 Ubenimex 1件: 86 💬 💬
322 Hematopoietic cell lineage 💬
 2件: FLT3, KIT 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
323 Hematopoietic cell lineage 💬
 2件: IL1R1, IL1R2 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬
324 Hematopoietic cell lineage 💬
 1件: IL6R 💬 Satralizumab 💬 Satralizumab 3件: 11, 13, 86 💬 💬
325 Hematopoietic cell lineage 💬
 1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬
326 Hematopoietic cell lineage 💬
 1件: KIT 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
327 Hematopoietic cell lineage 💬
 1件: KIT 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
328 Hematopoietic cell lineage 💬
 1件: MS4A1 💬 Rituximab 💬 Rituximab 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 💬
329 Hepatitis B 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
330 Hepatitis C 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
331 Hepatitis C 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
332 Hepatocellular carcinoma 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
333 Hepatocellular carcinoma 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
334 Hepatocellular carcinoma 💬
 1件: KEAP1 💬 Dimethyl fumarate 💬 Dimethyl fumarate 5件: 13, 49, 51, 86, 296 💬 💬
335 Hepatocellular carcinoma 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
336 Hepatocellular carcinoma 💬
 1件: NQO1 💬 Warfarin 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬
337 Herpes simplex virus 1 infection 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
338 HIF-1 signaling pathway 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
339 HIF-1 signaling pathway 💬
 1件: IL6R 💬 Satralizumab 💬 Satralizumab 3件: 11, 13, 86 💬 💬
340 HIF-1 signaling pathway 💬
 1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬
341 HIF-1 signaling pathway 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
342 Human cytomegalovirus infection 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
343 Human cytomegalovirus infection 💬
 1件: IL1R1 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬
344 Human cytomegalovirus infection 💬
 1件: IL6R 💬 Satralizumab 💬 Satralizumab 3件: 11, 13, 86 💬 💬
345 Human cytomegalovirus infection 💬
 1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬
346 Human cytomegalovirus infection 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
347 Human cytomegalovirus infection 💬
 1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
348 Human cytomegalovirus infection 💬
 1件: PDGFRA 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
349 Human cytomegalovirus infection 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
350 Human cytomegalovirus infection 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
351 Human cytomegalovirus infection 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
352 Human immunodeficiency virus 1 infection 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus</