Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Glioma 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
2 Glioma 💬
3件: BRAF, PDGFRB, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
3 Glioma 💬
3件: BRAF, PDGFRB, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
4 Glioma 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
5 Glioma 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
6 Glioma 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
7 Glioma 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
8 Glioma 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
9 Glioma 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
10 Glioma 💬
1件: EGFR 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
11 Glioma 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
12 Glioma 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
13 Glioma 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
14 Glioma 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
15 Glioma 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
16 Glioma 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
17 Glioma 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
18 Glioma 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
19 Glioma 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
20 Glioma 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
21 Glioma 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
22 Glioma 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
23 Glioma 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
24 Glioma 💬
1件: PDGFRA 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
25 Glioma 💬
1件: PDGFRA 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
26 Glioma 💬
2件: PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
27 Glioma 💬
2件: PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
28 Glioma 💬
2件: PDGFRA, PDGFRB 💬 D06402 💬 Sunitinib 2件: 28, 34 💬
29 Glioma 💬
2件: PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
30 Glioma 💬
1件: PDGFRB 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
31 Glioma 💬
1件: PDGFRB 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
32 Glioma 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
33 Glioma 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬