Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CCL2 5件: CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
2 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CD40 1件: CD40 💬
|
Bleselumab Bleselumab 💬
| Bleselumab | 222 1件: 222 💬
|
3 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CD40 1件: CD40 💬
|
Iscalimab Iscalimab 💬
| Iscalimab | 049 2件: 49, 53 💬
|
4 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CD40 1件: CD40 💬
|
Ravagalimab Ravagalimab 💬
| Ravagalimab | 053 2件: 53, 97 💬
|
5 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CD40LG 1件: CD40LG 💬
|
Toralizumab Toralizumab 💬
| Toralizumab | 063 1件: 63 💬
|
6 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IFNG 1件: IFNG 💬
|
Emapalumab Emapalumab 💬
| Emapalumab | 049 3件: 49, 65, 107 💬
|
7 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IFNG 1件: IFNG 💬
|
Fontolizumab Fontolizumab 💬
| Fontolizumab | 046 1件: 46 💬
|
8 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL12A 1件: IL12A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
9 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
10 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
11 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
12 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 1件: IL6 💬
|
Olokizumab Olokizumab 💬
| Olokizumab | 046 2件: 46, 96 💬
|
13 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 1件: IL6 💬
|
Siltuximab Siltuximab 💬
| Siltuximab | 028 2件: 28, 331 💬
|
14 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
15 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 2件: IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 5件: 28, 51, 85, 227, 331 💬
|
16 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
ITGAL 1件: ITGAL 💬
|
Efalizumab Efalizumab 💬
| Efalizumab | 011 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
|
17 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
MET 1件: MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
18 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 3件: 51, 85, 222 💬
|
19 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TLR9 1件: TLR9 💬
|
Cobitolimod Cobitolimod 💬
| Cobitolimod | 097 1件: 97 💬
|
20 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
21 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
|
22 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
23 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
|
24 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
25 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
|
26 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 1件: 46 💬
|
27 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 1件: 46 💬
|
28 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|