Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Melanoma 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
2 Melanoma 💬
3件: BRAF, PDGFRB, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
3 Melanoma 💬
3件: BRAF, PDGFRB, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
4 Melanoma 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
5 Melanoma 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
6 Melanoma 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
7 Melanoma 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
8 Melanoma 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
9 Melanoma 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
10 Melanoma 💬
1件: EGFR 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
11 Melanoma 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
12 Melanoma 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
13 Melanoma 💬
1件: FGF23 💬 D10913 💬 Burosumab 1件: 238 💬
14 Melanoma 💬
1件: FGFR1 💬 D11589 💬 Infigratinib 1件: 276 💬
15 Melanoma 💬
3件: FGFR1, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
16 Melanoma 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
17 Melanoma 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
18 Melanoma 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
19 Melanoma 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
20 Melanoma 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
21 Melanoma 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
22 Melanoma 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
23 Melanoma 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
24 Melanoma 💬
1件: MET 💬 D10062 💬 Cabozantinib 1件: 34 💬
25 Melanoma 💬
1件: PDGFRA 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
26 Melanoma 💬
1件: PDGFRA 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
27 Melanoma 💬
2件: PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
28 Melanoma 💬
2件: PDGFRA, PDGFRB 💬 D06402 💬 Sunitinib 2件: 28, 34 💬
29 Melanoma 💬
2件: PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
30 Melanoma 💬
1件: PDGFRB 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
31 Melanoma 💬
1件: PDGFRB 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
32 Melanoma 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
33 Melanoma 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬