Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Acute myeloid leukemia 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
2 Adipocytokine signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
3 AGE-RAGE signaling pathway in diabetic complications 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
4 Alcoholic liver disease 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
5 Alzheimer disease 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
6 Amoebiasis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
7 Antifolate resistance 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
8 Apoptosis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
9 B cell receptor signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
10 C-type lectin receptor signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
11 cAMP signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
12 Cellular senescence 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
13 Chagas disease 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
14 Chemical carcinogenesis - reactive oxygen species 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
15 Chemical carcinogenesis - receptor activation 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
16 Chemokine signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
17 Chronic myeloid leukemia 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
18 Cocaine addiction 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
19 Coronavirus disease - COVID-19 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
20 Cytosolic DNA-sensing pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
21 Diabetic cardiomyopathy 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
22 Epithelial cell signaling in Helicobacter pylori infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
23 Epstein-Barr virus infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
24 Fluid shear stress and atherosclerosis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
25 Hepatitis B 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
26 Hepatitis C 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
27 Herpes simplex virus 1 infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
28 HIF-1 signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
29 Human cytomegalovirus infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
30 Human immunodeficiency virus 1 infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
31 Human papillomavirus infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
32 Human T-cell leukemia virus 1 infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
33 IL-17 signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
34 Inflammatory bowel disease 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
35 Influenza A 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
36 Insulin resistance 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
37 Kaposi sarcoma-associated herpesvirus infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
38 Legionellosis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
39 Leishmaniasis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
40 Lipid and atherosclerosis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
41 Longevity regulating pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
42 MAPK signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
43 Measles 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
44 Mitophagy - animal 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
45 Neurotrophin signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
46 Neutrophil extracellular trap formation 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
47 NF-kappa B signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
48 NOD-like receptor signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
49 Non-alcoholic fatty liver disease 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
50 Osteoclast differentiation 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
51 Pancreatic cancer 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
52 Pathogenic Escherichia coli infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
53 Pathways in cancer 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
54 Pathways of neurodegeneration - multiple diseases 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
55 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
56 Pertussis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
57 PI3K-Akt signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
58 Prolactin signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
59 Prostate cancer 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
60 Ras signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
61 Relaxin signaling pathway 💬
1件: EDNRB 💬 Bosentan 💬 Bosentan 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
62 Relaxin signaling pathway 💬
1件: EDNRB 💬 Bosentan 💬 Bosentan 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
63 Relaxin signaling pathway 💬
1件: EDNRB 💬 Macitentan 💬 Macitentan 5件: 51, 85, 86, 88, 210 💬
64 Relaxin signaling pathway 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬
65 Relaxin signaling pathway 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 1件: 94 💬
66 Relaxin signaling pathway 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
67 Relaxin signaling pathway 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
68 Relaxin signaling pathway 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
69 Relaxin signaling pathway 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
70 Relaxin signaling pathway 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
71 Relaxin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
72 Relaxin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
73 Relaxin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬
74 Relaxin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
75 Relaxin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬
76 Relaxin signaling pathway 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
77 Relaxin signaling pathway 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
78 Relaxin signaling pathway 💬
1件: MMP13 💬 Apratastat 💬 Apratastat 1件: 46 💬
79 Relaxin signaling pathway 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬
80 Relaxin signaling pathway 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬
81 Relaxin signaling pathway 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
82 Relaxin signaling pathway 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
83 Relaxin signaling pathway 💬
1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
84 Relaxin signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
85 Relaxin signaling pathway 💬
1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
86 Relaxin signaling pathway 💬
1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
87 Relaxin signaling pathway 💬
1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
88 Relaxin signaling pathway 💬
1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬
89 Relaxin signaling pathway 💬
1件: TGFB1 💬 Fresolimumab 💬 Fresolimumab 3件: 51, 85, 222 💬
90 Relaxin signaling pathway 💬
1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 6件: 13, 34, 85, 87, 227, 280 💬
91 Relaxin signaling pathway 💬
1件: VEGFA 💬 Ranibizumab 💬 Ranibizumab 4件: 34, 166, 227, 301 💬
92 Relaxin signaling pathway 💬
2件: VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept 2件: 90, 166 💬
93 RIG-I-like receptor signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
94 Salmonella infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
95 Shigellosis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
96 Small cell lung cancer 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
97 Sphingolipid signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
98 T cell receptor signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
99 Th1 and Th2 cell differentiation 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
100 Th17 cell differentiation 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
101 TNF signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
102 Toll-like receptor signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
103 Toxoplasmosis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
104 Transcriptional misregulation in cancer 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
105 Tuberculosis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
106 Viral carcinogenesis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
107 Yersinia infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬