Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
BCL2 1件: BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 1件: 28 💬
|
| 2 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 3 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 4 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
CDK4 1件: CDK4 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 1件: 34 💬
|
| 5 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR 1件: EGFR 💬
|
Cetuximab Cetuximab 💬
| Cetuximab | 051 2件: 51, 86 💬
|
| 6 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR 1件: EGFR 💬
|
Erlotinib Erlotinib 💬
| Erlotinib | 094 1件: 94 💬
|
| 7 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR 1件: EGFR 💬
|
Gefitinib Gefitinib 💬
| Gefitinib | 075 1件: 75 💬
|
| 8 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR 1件: EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 1件: 34 💬
|
| 9 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR 2件: EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 3件: 34, 74, 75 💬
|
| 10 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR 2件: EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 1件: 34 💬
|
| 11 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR 2件: EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 12 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 1件: ESR1 💬
|
Danazol Danazol 💬
| Danazol | 060 5件: 60, 63, 64, 65, 285 💬
|
| 13 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 1件: ESR1 💬
|
Desogestrel Desogestrel 💬
| Desogestrel | 230 1件: 230 💬
|
| 14 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 1件: ESR1 💬
|
Ethinyl estradiol Ethinyl estradiol 💬
| Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬
|
| 15 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Clomifene Clomifene 💬
| Clomifene | 074 1件: 74 💬
|
| 16 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 1件: 53 💬
|
| 17 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 1件: 53 💬
|
| 18 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Estradiol Estradiol 💬
| Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬
|
| 19 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Estradiol valerate Estradiol valerate 💬
| Estradiol valerate | 065 1件: 65 💬
|
| 20 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Estriol Estriol 💬
| Estriol | 013 2件: 13, 227 💬
|
| 21 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Estriol tripropionate Estriol tripropionate 💬
| Estriol | 013 2件: 13, 227 💬
|
| 22 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Fulvestrant Fulvestrant 💬
| Fulvestrant | 049 2件: 49, 86 💬
|
| 23 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Mestranol Mestranol 💬
| Mestranol | 046 2件: 46, 49 💬
|
| 24 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Prasterone Prasterone 💬
| Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬
|
| 25 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Raloxifene Raloxifene 💬
| Raloxifene | 046 1件: 46 💬
|
| 26 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 2件: ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 3件: 2 , 113, 227 💬
|
| 27 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 1件: 232 💬
|
| 28 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 29 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 1件: 51 💬
|
| 30 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 1件: 34 💬
|
| 31 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 32 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 1件: 34 💬
|
| 33 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 1件: 34 💬
|
| 34 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 35 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 2件: 113, 222 💬
|
| 36 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 1件: 8 💬
|
| 37 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
| 38 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 39 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬
|
Temsirolimus Temsirolimus 💬
| Temsirolimus | 013 1件: 13 💬
|
| 40 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
PIK3CA 1件: PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 1件: 138 💬
|
| 41 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 2件: 53, 65 💬
|
| 42 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
PIK3CD 1件: PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 3件: 35, 53, 61 💬
|
| 43 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
SRC 1件: SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 2件: 2 , 67 💬
|
| 44 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
SRC 1件: SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 2件: 51, 85 💬
|
| 45 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
SRC 1件: SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 2件: 51, 85 💬
|
| 46 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
SRC 1件: SRC 💬
|
Saracatinib Saracatinib 💬
| Saracatinib | 006 3件: 6 , 89, 272 💬
|