Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Th17 cell differentiation 💬
3件: CD3D, CD3E, CD3G 💬 Otelixizumab 💬 Otelixizumab 1件: 46 💬 💬
2 Th17 cell differentiation 💬
3件: CD3D, CD3E, CD3G 💬 Visilizumab 💬 Visilizumab 2件: 96, 97 💬 💬
3 Th17 cell differentiation 💬
1件: CD3E 💬 Mosunetuzumab 💬 Mosunetuzumab 1件: 49 💬 💬
4 Th17 cell differentiation 💬
1件: CD4 💬 Zanolimumab 💬 Zanolimumab 1件: 46 💬 💬
5 Th17 cell differentiation 💬
1件: IFNG 💬 Emapalumab 💬 Emapalumab 3件: 49, 65, 107 💬 💬
6 Th17 cell differentiation 💬
1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬 💬
7 Th17 cell differentiation 💬
2件: IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬 💬
8 Th17 cell differentiation 💬
1件: IL17A 💬 Ixekizumab 💬 Ixekizumab 8件: 36, 37, 46, 107, 160, 162, 269, 271 💬 💬
9 Th17 cell differentiation 💬
1件: IL17A 💬 Secukinumab 💬 Secukinumab 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 💬
10 Th17 cell differentiation 💬
1件: IL17A 💬 Tibulizumab 💬 Tibulizumab 1件: 53 💬 💬
11 Th17 cell differentiation 💬
2件: IL17A, IL17F 💬 Bimekizumab 💬 Bimekizumab 3件: 46, 97, 271 💬 💬
12 Th17 cell differentiation 💬
1件: IL1B 💬 Canakinumab 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬
13 Th17 cell differentiation 💬
1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬 💬
14 Th17 cell differentiation 💬
1件: IL1B 💬 Rilonacept 💬 Rilonacept 4件: 51, 106, 107, 266 💬 💬
15 Th17 cell differentiation 💬
2件: IL1B, IL6 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
16 Th17 cell differentiation 💬
1件: IL1R1 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬
17 Th17 cell differentiation 💬
1件: IL22 💬 Efmarodocokin alfa 💬 Efmarodocokin alfa 2件: 96, 97 💬 💬
18 Th17 cell differentiation 💬
1件: IL23A 💬 Brazikumab 💬 Brazikumab 2件: 96, 97 💬 💬
19 Th17 cell differentiation 💬
1件: IL23A 💬 Guselkumab 💬 Guselkumab 5件: 37, 41, 51, 96, 97 💬 💬
20 Th17 cell differentiation 💬
1件: IL23A 💬 Mirikizumab 💬 Mirikizumab 3件: 37, 96, 97 💬 💬
21 Th17 cell differentiation 💬
1件: IL23A 💬 Risankizumab 💬 Risankizumab 4件: 37, 96, 97, 271 💬 💬
22 Th17 cell differentiation 💬
1件: IL23A 💬 Tildrakizumab 💬 Tildrakizumab 2件: 162, 271 💬 💬
23 Th17 cell differentiation 💬
1件: IL23A 💬 Ustekinumab 💬 Ustekinumab 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬
24 Th17 cell differentiation 💬
1件: IL2RA 💬 Basiliximab 💬 Basiliximab 6件:  2 , 50, 66, 97, 222, 228 💬 💬
25 Th17 cell differentiation 💬
1件: IL2RA 💬 Daclizumab 💬 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 💬
26 Th17 cell differentiation 💬
3件: IL2RA, IL2RB, IL2RG 💬 Aldesleukin 💬 Aldesleukin 6件:  2 , 35, 49, 65, 96, 97 💬 💬
27 Th17 cell differentiation 💬
1件: IL4 💬 Binetrakin 💬 Binetrakin 1件: 46 💬 💬
28 Th17 cell differentiation 💬
1件: IL4R 💬 Dupilumab 💬 Dupilumab 5件: 51, 97, 98, 160, 162 💬 💬
29 Th17 cell differentiation 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬 💬
30 Th17 cell differentiation 💬
1件: IL6 💬 Pomalidomide 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬 💬
31 Th17 cell differentiation 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬 💬
32 Th17 cell differentiation 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬 💬
33 Th17 cell differentiation 💬
1件: IL6R 💬 Sarilumab 💬 Sarilumab 5件: 41, 46, 84, 107, 271 💬 💬
34 Th17 cell differentiation 💬
1件: IL6R 💬 Satralizumab 💬 Satralizumab 3件: 11, 13, 86 💬 💬
35 Th17 cell differentiation 💬
1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬
36 Th17 cell differentiation 💬
1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 1件: 84 💬 💬
37 Th17 cell differentiation 💬
1件: JAK1 💬 Filgotinib 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬 💬
38 Th17 cell differentiation 💬
1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬 💬
39 Th17 cell differentiation 💬
1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 💬
40 Th17 cell differentiation 💬
2件: JAK1, JAK2 💬 Baricitinib 💬 Baricitinib 13件:  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬
41 Th17 cell differentiation 💬
2件: JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib 3件: 60, 65, 228 💬 💬
42 Th17 cell differentiation 💬
3件: JAK1, JAK2, JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬 💬
43 Th17 cell differentiation 💬
4件: JAK1, JAK2, JAK3, TYK2 💬 Tofacitinib 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬
44 Th17 cell differentiation 💬
1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
45 Th17 cell differentiation 💬
1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
46 Th17 cell differentiation 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬 💬
47 Th17 cell differentiation 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬 💬
48 Th17 cell differentiation 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
49 Th17 cell differentiation 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
50 Th17 cell differentiation 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
51 Th17 cell differentiation 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬 💬
52 Th17 cell differentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Cyclosporine 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬
53 Th17 cell differentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Pimecrolimus 💬 Pimecrolimus 1件: 160 💬 💬
54 Th17 cell differentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
55 Th17 cell differentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
56 Th17 cell differentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Voclosporin 💬 Voclosporin 2件: 49, 222 💬 💬
57 Th17 cell differentiation 💬
1件: PRKCQ 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬 💬
58 Th17 cell differentiation 💬
1件: RARA 💬 Fenretinide 💬 Fenretinide 1件: 299 💬 💬
59 Th17 cell differentiation 💬
1件: RARA 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬 💬
60 Th17 cell differentiation 💬
1件: RARA 💬 Tamibarotene 💬 Tamibarotene 2件: 26, 96 💬 💬
61 Th17 cell differentiation 💬
1件: RARA 💬 Tretinoin 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬 💬
62 Th17 cell differentiation 💬
1件: RARA 💬 Vitamin A 💬 Vitamin A 3件: 13, 53, 90 💬 💬
63 Th17 cell differentiation 💬
4件: RARA, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin 1件: 37 💬 💬
64 Th17 cell differentiation 💬
4件: RARA, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin 1件: 49 💬 💬
65 Th17 cell differentiation 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬 💬
66 Th17 cell differentiation 💬
3件: RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬 💬
67 Th17 cell differentiation 💬
1件: TGFB1 💬 Fresolimumab 💬 Fresolimumab 3件: 51, 85, 222 💬 💬
68 Th17 cell differentiation 💬
1件: TYK2 💬 Deucravacitinib 💬 Deucravacitinib 3件: 49, 96, 97 💬 💬