Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Regulation of actin cytoskeleton 💬
1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬 💬
2 Regulation of actin cytoskeleton 💬
3件: BRAF, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
3 Regulation of actin cytoskeleton 💬
1件: C5 💬 Crovalimab 💬 Crovalimab 2件: 62, 109 💬 💬
4 Regulation of actin cytoskeleton 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222 💬 💬
5 Regulation of actin cytoskeleton 💬
1件: C5 💬 Nomacopan 💬 Nomacopan 3件: 62, 109, 162 💬 💬
6 Regulation of actin cytoskeleton 💬
1件: C5 💬 Pozelimab 💬 Pozelimab 2件: 11, 62 💬 💬
7 Regulation of actin cytoskeleton 💬
1件: C5 💬 Ravulizumab 💬 Ravulizumab 7件:  2 , 11, 13, 50, 62, 66, 109 💬 💬
8 Regulation of actin cytoskeleton 💬
1件: C5 💬 Vilobelimab 💬 Vilobelimab 3件: 43, 44, 269 💬 💬
9 Regulation of actin cytoskeleton 💬
1件: C5 💬 Zilucoplan 💬 Zilucoplan 3件:  2 , 11, 62 💬 💬
10 Regulation of actin cytoskeleton 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine 2件:  2 , 299 💬 💬
11 Regulation of actin cytoskeleton 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
12 Regulation of actin cytoskeleton 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬 💬
13 Regulation of actin cytoskeleton 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin 3件:  6 , 13, 53 💬 💬
14 Regulation of actin cytoskeleton 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine 1件: 226 💬 💬
15 Regulation of actin cytoskeleton 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine 1件:  2  💬 💬
16 Regulation of actin cytoskeleton 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl 2件:  5 ,  6  💬 💬
17 Regulation of actin cytoskeleton 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide 1件:  6  💬 💬
18 Regulation of actin cytoskeleton 💬
2件: CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine 1件:  6  💬 💬
19 Regulation of actin cytoskeleton 💬
2件: CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine 3件:  6 , 53, 299 💬 💬
20 Regulation of actin cytoskeleton 💬
1件: CHRM3 💬 Cevimeline 💬 Cevimeline 1件: 53 💬 💬
21 Regulation of actin cytoskeleton 💬
1件: CHRM3 💬 Darifenacin 💬 Darifenacin 2件:  6 , 13 💬 💬
22 Regulation of actin cytoskeleton 💬
1件: CHRM3 💬 Solifenacin 💬 Solifenacin 3件:  6 , 13, 53 💬 💬
23 Regulation of actin cytoskeleton 💬
1件: CHRM3 💬 Tolterodine 💬 Tolterodine 2件: 17, 53 💬 💬
24 Regulation of actin cytoskeleton 💬
1件: CXCR4 💬 Plerixafor 💬 Plerixafor 5件: 19, 20, 65, 285, 299 💬 💬
25 Regulation of actin cytoskeleton 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
26 Regulation of actin cytoskeleton 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 1件: 94 💬 💬
27 Regulation of actin cytoskeleton 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬 💬
28 Regulation of actin cytoskeleton 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬 💬
29 Regulation of actin cytoskeleton 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬 💬
30 Regulation of actin cytoskeleton 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬 💬
31 Regulation of actin cytoskeleton 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬 💬
32 Regulation of actin cytoskeleton 💬
1件: F2 💬 Dabigatran 💬 Dabigatran 5件: 51, 75, 85, 91, 124 💬 💬
33 Regulation of actin cytoskeleton 💬
1件: F2 💬 Dabigatran etexilate 💬 Dabigatran etexilate 2件: 51, 75 💬 💬
34 Regulation of actin cytoskeleton 💬
1件: F2 💬 Thrombomodulin alfa 💬 Thrombomodulin Alfa 1件: 85 💬 💬
35 Regulation of actin cytoskeleton 💬
1件: FGF23 💬 Burosumab 💬 Burosumab 1件: 238 💬 💬
36 Regulation of actin cytoskeleton 💬
3件: FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib 1件: 276 💬 💬
37 Regulation of actin cytoskeleton 💬
5件: FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬 💬
38 Regulation of actin cytoskeleton 💬
1件: FGFR2 💬 Palifermin 💬 Palifermin 5件: 13, 36, 38, 39, 65 💬 💬
39 Regulation of actin cytoskeleton 💬
1件: ITGA4 💬 Firategrast 💬 Firategrast 1件: 13 💬 💬
40 Regulation of actin cytoskeleton 💬
1件: ITGA4 💬 Natalizumab 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬 💬
41 Regulation of actin cytoskeleton 💬
2件: ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab 2件: 96, 97 💬 💬
42 Regulation of actin cytoskeleton 💬
2件: ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab 3件: 94, 96, 97 💬 💬
43 Regulation of actin cytoskeleton 💬
1件: ITGAL 💬 Efalizumab 💬 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬
44 Regulation of actin cytoskeleton 💬
1件: ITGB7 💬 Etrolizumab 💬 Etrolizumab 2件: 96, 97 💬 💬
45 Regulation of actin cytoskeleton 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬 💬
46 Regulation of actin cytoskeleton 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬 💬
47 Regulation of actin cytoskeleton 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬 💬
48 Regulation of actin cytoskeleton 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬 💬
49 Regulation of actin cytoskeleton 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬 💬
50 Regulation of actin cytoskeleton 💬
1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
51 Regulation of actin cytoskeleton 💬
2件: PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
52 Regulation of actin cytoskeleton 💬
2件: PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬 💬
53 Regulation of actin cytoskeleton 💬
2件: PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
54 Regulation of actin cytoskeleton 💬
2件: PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
55 Regulation of actin cytoskeleton 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬 💬
56 Regulation of actin cytoskeleton 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬 💬
57 Regulation of actin cytoskeleton 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬 💬
58 Regulation of actin cytoskeleton 💬
2件: ROCK1, ROCK2 💬 Fasudil 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬 💬
59 Regulation of actin cytoskeleton 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 2件: 51, 85 💬 💬
60 Regulation of actin cytoskeleton 💬
1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬 💬
61 Regulation of actin cytoskeleton 💬
1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬 💬