Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬
2 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
3 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬
4 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine 1件:  6  💬
5 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬
6 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine 2件: 50, 81 💬
7 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬
8 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
9 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine 1件: 226 💬
10 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
11 GnRH secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬
12 GnRH secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 Flunarizine 💬 Flunarizine 1件: 149 💬
13 GnRH secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid 14件:  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
14 GnRH secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 Zonisamide 💬 Zonisamide 1件:  6  💬
15 GnRH secretion 💬
1件: ESR2 💬 Clomifene 💬 Clomifene 1件: 74 💬
16 GnRH secretion 💬
1件: ESR2 💬 Estetrol 💬 Estetrol 1件: 53 💬
17 GnRH secretion 💬
1件: ESR2 💬 Estetrol 💬 Estetrol 1件: 53 💬
18 GnRH secretion 💬
1件: ESR2 💬 Estradiol 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
19 GnRH secretion 💬
1件: ESR2 💬 Estradiol valerate 💬 Estradiol valerate 1件: 65 💬
20 GnRH secretion 💬
1件: ESR2 💬 Estriol 💬 Estriol 2件: 13, 227 💬
21 GnRH secretion 💬
1件: ESR2 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
22 GnRH secretion 💬
1件: ESR2 💬 Fulvestrant 💬 Fulvestrant 2件: 49, 86 💬
23 GnRH secretion 💬
1件: ESR2 💬 Mestranol 💬 Mestranol 2件: 46, 49 💬
24 GnRH secretion 💬
1件: ESR2 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
25 GnRH secretion 💬
1件: ESR2 💬 Raloxifene 💬 Raloxifene 1件: 46 💬
26 GnRH secretion 💬
1件: ESR2 💬 Tamoxifen 💬 Tamoxifen 3件:  2 , 113, 227 💬
27 GnRH secretion 💬
2件: GABBR1, GABBR2 💬 Arbaclofen 💬 Arbaclofen 2件: 13, 206 💬
28 GnRH secretion 💬
2件: GABBR1, GABBR2 💬 Arbaclofen placarbil 💬 Arbaclofen Placarbil 1件: 13 💬
29 GnRH secretion 💬
2件: GABBR1, GABBR2 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
30 GnRH secretion 💬
2件: GABBR1, GABBR2 💬 Valiloxybate 💬 Valiloxybate 1件:  6  💬
31 GnRH secretion 💬
1件: KCNJ11 💬 Diazoxide 💬 Diazoxide 2件: 13, 193 💬
32 GnRH secretion 💬
1件: KCNJ11 💬 Minoxidil 💬 Minoxidil 1件: 179 💬
33 GnRH secretion 💬
1件: KCNJ11 💬 Repaglinide 💬 Repaglinide 4件:  6 , 21, 46, 299 💬
34 GnRH secretion 💬
3件: KCNJ11, KCNJ3, KCNJ5 💬 Amiodarone 💬 Amiodarone 2件: 28, 127 💬
35 GnRH secretion 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
36 GnRH secretion 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
37 GnRH secretion 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬
38 GnRH secretion 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
39 GnRH secretion 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬
40 GnRH secretion 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬
41 GnRH secretion 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
42 GnRH secretion 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
43 GnRH secretion 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
44 GnRH secretion 💬
1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬