Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
BCL2 1件: BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 1件: 28 💬 💬 |
| 2 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
CASP9 1件: CASP9 💬 |
Rimiducid Rimiducid 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 💬 |
| 3 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
ERBB4 1件: ERBB4 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 1件: 34 💬 💬 |
| 4 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIA1 2件: GRIA1, GRIA2 💬 |
Perampanel Perampanel 💬 |
Perampanel | 002 3件: 2 , 6 , 144 💬 💬 |
| 5 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIA1 2件: GRIA1, GRIA2 💬 |
Talampanel Talampanel 💬 |
Talampanel | 002 2件: 2 , 6 💬 💬 |
| 6 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIA1 2件: GRIA1, GRIA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬 💬 |
| 7 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIA1 7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
| 8 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Acamprosate Acamprosate 💬 |
Acamprosate | 006 2件: 6 , 206 💬 💬 |
| 9 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Amantadine Amantadine 💬 |
Amantadine | 006 4件: 6 , 8 , 13, 127 💬 💬 |
| 10 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Esketamine Esketamine 💬 |
Esketamine | 002 3件: 2 , 4 , 70 💬 💬 |
| 11 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Ketamine Ketamine 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 💬 |
| 12 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Latrepirdine Latrepirdine 💬 |
Latrepirdine | 008 1件: 8 💬 💬 |
| 13 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Memantine Memantine 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 💬 |
| 14 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
Dextromethorphan Dextromethorphan 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬 |
| 15 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
HDAC6 1件: HDAC6 💬 |
Vorinostat Vorinostat 💬 |
Vorinostat | 075 2件: 75, 96 💬 💬 |
| 16 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MAP3K5 1件: MAP3K5 💬 |
Selonsertib Selonsertib 💬 |
Selonsertib | 086 1件: 86 💬 💬 |
| 17 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 2件: 113, 222 💬 💬 |
| 18 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 1件: 8 💬 💬 |
| 19 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
| 20 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
| 21 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 1件: 13 💬 💬 |
| 22 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
| 23 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Pimecrolimus Pimecrolimus 💬 |
Pimecrolimus | 160 1件: 160 💬 💬 |
| 24 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
| 25 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Tacrolimus Tacrolimus 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬 |
| 26 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Voclosporin Voclosporin 💬 |
Voclosporin | 049 2件: 49, 222 💬 💬 |
| 27 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
| 28 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PSMB5 1件: PSMB5 💬 |
Carfilzomib Carfilzomib 💬 |
Carfilzomib | 028 1件: 28 💬 💬 |
| 29 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PSMB5 1件: PSMB5 💬 |
Ixazomib Ixazomib 💬 |
Ixazomib | 013 5件: 13, 16, 28, 51, 61 💬 💬 |
| 30 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
SIGMAR1 1件: SIGMAR1 💬 |
Blarcamesine Blarcamesine 💬 |
Blarcamesine | 156 1件: 156 💬 💬 |
| 31 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
SIGMAR1 1件: SIGMAR1 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 💬 |
| 32 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
SOD1 1件: SOD1 💬 |
Tofersen Tofersen 💬 |
Tofersen | 002 1件: 2 💬 💬 |
| 33 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
| 34 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
| 35 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
| 36 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
| 37 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
| 38 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
| 39 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 1件: 46 💬 💬 |
| 40 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 1件: 46 💬 💬 |
| 41 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
| 42 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 5件: 28, 51, 85, 227, 331 💬 💬 |
| 43 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
| 44 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Belantamab mafodotin Belantamab mafodotin 💬 |
Belantamab mafodotin | 028 1件: 28 💬 💬 |
| 45 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Brentuximab vedotin Brentuximab vedotin 💬 |
Brentuximab vedotin | 049 2件: 49, 51 💬 💬 |
| 46 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 47 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Paclitaxel Paclitaxel 💬 |
Paclitaxel | 046 2件: 46, 85 💬 💬 |
| 48 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vinblastine Vinblastine 💬 |
Vinblastine | 034 2件: 34, 65 💬 💬 |
| 49 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Vincristine Vincristine 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 💬 |